David

No one knows us quite the same way as the men and women who sit beside us in department meetings and crowd the office refrigerator with their labeled yogurts. Every office is a family of sorts, and the Chicago ad agency Joshua Ferris brilliantly depicts in his debut novel is family at its strangest and best. The characters in Then We Came to an End cope with a business downturn in the time-honored way: through gossip, secret romance, elaborate pranks, and increasingly frequent coffee breaks.

A scientific experiment begins, and as the button is pressed, the unexpected occurs: everyone in the world goes to sleep for a few moments while everyone's consciousness is catapulted more than twenty years into the future. At the end of those moments, when the world reawakens, all human life is transformed by foreknowledge.

In this episode... Steve on Feng Shui; The think tank; Karl's perfect life; Karl's problem with neuroanatomy; Cogito Ergo Summat; Work ethics; Post-pesticidal remorse; Karl's holiday anhedonia; Curry night at Auntie Nora's; The Zen of Munchies; Karl's confectionery-based analogies; Transplant bollocks; Karl gets economical with his facts; Tribal numeracy; Small talk at the bar.

Here's the first in a series of in-depth discussions on a variety of subjects relating to humanity's greatest endeavors. Around the table, Ricky Gervais, Steve Merchant, and the glabrous luminary Karl Pilkington. In this episode, MEDICINE, we explore the treatment of human ailments through history - from trepanation (or 'oles in the 'ed) in early tribal societies right through to the possible, if improbable, future of medical technology.