Annette Bargas / John Hudspeth

It’s 1929 in New York City. In an apartment high above Lexington Avenue, the painter Georgia O’Keeffe feels stuck. At 42, she should be at the apex of her powers as an artist, and yet something is missing. Her husband - the gallerist Alfred Stieglitz, who helped build her reputation in the art world - has grown needy and insecure, not to mention unfaithful. More than this, her work has lost its fire, and she knows it. The calla lilies and poppies for which she is revered now seem careful, predictable.

This transcendent story follows four college friends who move to New York City, buoyed by ambition: Willem, an aspiring actor; JB, an artist; Malcolm, an architect; and, at the center, Jude, a withdrawn, brilliant attorney haunted by an unspeakable past. Through decades of shared and separate lives, Jude’s suffering - and its impact on those who love him - raises questions about the limits of human endurance, the possibility for redemption, and the meaning of friendship.