Chemist Elizabeth Zott is not your average woman. In fact, Elizabeth Zott would be the first to point out that there is no such thing as an average woman. But it’s the early 1960s and her all-male team at Hastings Research Institute takes a very unscientific view of equality. Except for one: Calvin Evans; the lonely, brilliant, Nobel–prize nominated grudge-holder who falls in love with—of all things—her mind. True chemistry results.

Spanning the years 1900 to 1977, The Covenant of Water is set in Kerala, on South India’s Malabar Coast, and follows three generations of a family that suffers a peculiar affliction: in every generation, at least one person dies by drowning—and in Kerala, water is everywhere. At the turn of the century, a twelve-year-old girl from Kerala’s long-existing Christian community, grieving the death of her father, is sent by boat to her wedding, where she will meet her forty-year-old husband for the first time.

Kentucky, 1850. An enslaved groom named Jarret and a bay foal forge a bond of understanding that will carry the horse to record-setting victories across the South. When the nation erupts in civil war, an itinerant young artist who has made his name on paintings of the racehorse takes up arms for the Union. On a perilous night, he reunites with the stallion and his groom, very far from the glamor of any racetrack.

Set in the mountains of southern Appalachia, Demon Copperhead is the story of a boy born to a teenaged single mother in a single-wide trailer, with no assets beyond his dead father’s good looks and copper-colored hair, a caustic wit, and a fierce talent for survival. Relayed in his own unsparing voice, Demon braves the modern perils of foster care, child labor, derelict schools, athletic success, addiction, disastrous loves, and crushing losses.

In the spring of 2020, Lara’s three daughters return to the family's orchard in Northern Michigan. While picking cherries, they beg their mother to tell them the story of Peter Duke, a famous actor with whom she shared both a stage and a romance years before at a theater company called Tom Lake. As Lara recalls the past, her daughters examine their own lives and relationship with their mother, and are forced to reconsider the world and everything they thought they knew.

After Tova Sullivan’s husband died, she began working the night shift at the Sowell Bay Aquarium, mopping floors and tidying up. Keeping busy has always helped her cope, which she’s been doing since her eighteen-year-old son, Erik, mysteriously vanished on a boat in Puget Sound over thirty years ago. Tova becomes acquainted with curmudgeonly Marcellus, a giant Pacific octopus living at the aquarium. Marcellus knows more than anyone can imagine but wouldn’t dream of lifting one of his eight arms for his human captors—until he forms a remarkable friendship with Tova.

Sam and Sadie—two college friends, often in love, but never lovers—become creative partners in a dazzling and intricately imagined world of video game design, where success brings them fame, joy, tragedy, duplicity, and, ultimately, a kind of immortality. It is a love story, but not one you have heard before.

William Waters grew up in a house silenced by tragedy, where his parents could hardly bear to look at him, much less love him—so when he meets the spirited and ambitious Julia Padavano in his freshman year of college, it’s as if the world has lit up around him. With Julia comes her family, as she and her three sisters are inseparable: Sylvie, the family’s dreamer, is happiest with her nose in a book; Cecelia is a free-spirited artist; and Emeline patiently takes care of them all.

A landslide has closed the Korowai Pass on New Zealand’s South Island, cutting off the town of Thorndike and leaving a sizable farm abandoned. The disaster presents an opportunity for Birnam Wood, an undeclared, unregulated, sometimes-criminal, sometimes-philanthropic guerrilla gardening collective that plants crops wherever no one will notice. For years, the group has struggled to break even. To occupy the farm at Thorndike would mean a shot at solvency at last. But the enigmatic American billionaire Robert Lemoine also has an interest in the place.

Among the most celebrated and beloved novels of 2021, Anthony Doerr’s gorgeous third novel is a triumph of imagination and compassion, a soaring story about children on the cusp of adulthood in worlds in peril, who find resilience, hope—and a book. In Cloud Cuckoo Land, Doerr has created a magnificent tapestry of times and places that reflects our vast interconnectedness—with other species, with each other, with those who lived before us, and with those who will be here after we’re gone.

There lived a girl named Petra Peña, who wanted nothing more than to be a storyteller, like her abuelita. But Petra's world is ending. Earth has been destroyed by a comet, and only a few hundred scientists and their children - among them Petra and her family - have been chosen to journey to a new planet. They are the ones who must carry on the human race. Hundreds of years later, Petra wakes to this new planet - and the discovery that she is the only person who remembers Earth. A sinister Collective has taken over the ship during its journey.

Authors June Hayward and Athena Liu were supposed to be twin rising stars: same year at Yale, same debut year in publishing. But Athena’s a cross-genre literary darling, and June didn’t even get a paperback release. Nobody wants stories about basic white girls, June thinks. So when June witnesses Athena’s death in a freak accident, she acts on impulse: she steals Athena’s just-finished masterpiece, an experimental novel about the unsung contributions of Chinese laborers to the British and French war efforts during World War I.

Tuscany, 1944: As Allied troops advance and bombs fall around deserted villages, a young English soldier, Ulysses Temper, finds himself in the wine cellar of a deserted villa. There, he has a chance encounter with Evelyn Skinner, a middle-aged art historian who has come to Italy to salvage paintings from the ruins and recall long-forgotten memories of her own youth. In each other, Ulysses and Evelyn find a kindred spirit amidst the rubble of war-torn Italy, and set off on a course of events that will shape Ulysses's life for the next four decades.

Alejandra no longer knows who she is. To her husband, she is a wife, and to her children, a mother. To her own adoptive mother, she is a daughter. But they cannot see who Alejandra has become: a woman struggling with a darkness that threatens to consume her. Nor can they see what Alejandra sees. In times of despair, a ghostly vision appears to her, the apparition of a crying woman in a ragged white gown.

The Latecomer follows the story of the wealthy, New York City-based Oppenheimer family, from the first meeting of parents Salo and Johanna, under tragic circumstances, to their triplets born during the early days of IVF. As children, the three siblings—Harrison, Lewyn, and Sally—feel no strong familial bond and cannot wait to go their separate ways, even as their father becomes more distanced and their mother more desperate. When the triplets leave for college, Johanna, faced with being truly alone, makes the decision to have a fourth child.

Three people find their way back from loss and loneliness to a different kind of belonging in this deeply moving novel. Arthur, an old widower struggling to overcome his grief, meets Maddy, a troubled teenage girl who avoids school by hiding out where Arthur goes every day for lunch. The two strike up a friendship that draws them out of isolation.

When we last saw Zippy, she was oblivious to the storm that was brewing in her home. Her mother, Delonda, had literally just gotten up off the couch and ridden her rickety bicycle down the road. Her dad was off somewhere, gambling or "working." And Zippy was lost in her own fabulous world of exploring the fringes of Moorland, Indiana.

In the middle of her life, Nan decides to leave her husband at home and begin an impromptu trek across the country, carrying with her a turquoise leather journal she intends to fill. The Pull of the Moon is a novel about a woman coming to terms with issues of importance to all women. In her journal, Nan addresses the thorniness - and the allure - of marriage, the sweet ties to children, and the gifts and lessons that come from random encounters.

A young woman sits in jail, accused of the mercy killing of her dying mother. She didn't do it, but she thinks she knows who did. In the last months of her life, Ellen Gulden's mother revealed startling secrets that challenged everything Ellen believed about her family. Now, in jail, Ellen believes those secrets will tell her who had the courage to end her mother's suffering.

The first step to letting go of the past is forgiving it …Every day of her life Julia Rich lives with the memory of a horrible accident she caused long ago. In the years since, she has tried to hide her guilt in the quiet routine of teaching at a small South Carolina college, avoiding close relationships with family and would-be friends. But one day a phone call from Carmen, a niece she has never met, disrupts her carefully controlled world.

Meet Dolores Price. She's 13, wise-mouthed but wounded, having bid her childhood goodbye. Beached like a whale in front of her bedroom TV, she spends the next few years nourishing herself with the Mallomars, potato chips, and Pepsi her anxious mother supplies. When she finally rolls into young womanhood at 257 pounds, Dolores is no stronger and life is no kinder. But this time she's determined to rise to the occasion and give herself one more chance before really going belly-up.

Seventh grader Estefania "Stef" Soto is itching to shake off the onion-and-cilantro embrace of Tia Perla, her family's taco truck. She wants nothing more than for her dad to get a normal job and for Tia Perla to be put out to pasture. It's no fun being known as the "Taco Queen" at school. But just when new city regulations are proposed, and her family's livelihood is threatened, she will have to become the truck's unlikely champion.

Leigh is the mother of high-achieving, popular high school senior Kara. Their relationship is already strained for reasons Leigh does not fully understand when, in a moment of carelessness, Kara makes a mistake that ends in tragedy, the effects of which not only divide Leigh's family, but polarize the entire community.

Duchess Day Radley is a 13-year-old self-proclaimed outlaw. Rules are for other people. She is the fierce protector of her five-year-old brother, Robin, and the parent to her mother, Star, a single mom incapable of taking care of herself, let alone her two kids. Walk has never left the coastal California town where he and Star grew up. He may have become the chief of police, but he’s still trying to heal the old wound of having given the testimony that sent his best friend, Vincent King, to prison decades before. And he's in overdrive protecting Duchess and her brother.

Lone Stars follows the arc of four generations of a Texan family in a changing America. Julian Warner, a father at last, wrestles with a question his husband posed: what will you tell our son about the people you came from, now that they're gone? Finding the answers takes Julian back in time to Eisenhower's immigration border raids, an epistolary love affair during the Vietnam War, crumbling marriages, queer migrations to Cambridge and New York, up to the disorienting polarization of Obama's second term.

Clare and Henry have known each other since Clare was six and Henry was 36. They were married when Clare was 23 and Henry was 31. Impossible but true, because Henry is one of the first people diagnosed with Chrono-Displacement Disorder: periodically his genetic clock resets and he finds himself misplaced in time, pulled to moments of emotional gravity from his life, past and future. His disappearances are spontaneous, his experiences unpredictable, alternately harrowing and amusing.

Caroline serves others with little time to enjoy the sweeter parts of life. Until her old boyfriend returns to town - and she's given a second chance at first love. Life hasn't always been so sweet for Caroline Sweeny. She sacrifices her desires for others - unlike her mother who abandoned their family years ago. But when a friend challenges her to accept an exciting job adventure in Spain, Caroline says "yes" to a new destiny. But before she can pack her bags, Caroline suddenly finds herself the new owner of the run-down Frogmore Cafe - and forced to choose: Her friends or her future?

This powerful and haunting memoir details the years Paula McLain and her two sisters spent as foster children after being abandoned by both parents in California in the early 1970s. As wards of the State, the sisters spent the next 14 years moving from foster home to foster home. The dislocations, confusions, and odd pleasures of an unrooted life form the basis of one of the most compelling memoirs in recent years - a book in the tradition of Jo Ann Beard's The Boys of My Youth and Mary Karr's The Liars' Club.

Emily Bell believes in destiny. To her, being forced to sing a solo in the church choir - despite her average voice - is fate: because it's while she's singing that she first sees Sam. At first sight they are connected. Sam Border wishes he could escape, but there's nowhere for him to run. He and his little brother, Riddle, have spent their entire lives constantly uprooted by their unstable father. As Sam and Riddle are welcomed into the Bells' lives, they witness the warmth and protection of a family for the first time.

For years, Edna Miller has found herself drawn to Emery Hoschtettler with an attraction she can explain no better than she can put a stop to it. Other suitors come and go, but none make her feel the way she feels around Emery - that incredible floating feeling, as if she was walking on air, mixed with a painful desperation to be ever nearer to him. Despite the fact that Emery seldom seems to pay her much attention, she decides it would be unfair to marry anyone else when her heart longs only for him. He hasn’t seriously dated anyone else either.