Dr. W. Lee Warren, a practicing brain surgeon, assumed he knew most outcomes for people with glioblastoma, head injuries, and other health-care problems. Yet even as he tried to give patients hope, his own heart would sink as he realized, I've seen the end of you. But it became far more personal when the acclaimed doctor experienced an unimaginable family tragedy. That's when he reached the end of himself. Gripping medical stories serve as the backdrop for a raw, honest look at how we can remain on solid ground when everything goes wrong.

Delia Ephron had struggled through several years of heartbreak. She’d lost her sister, Nora, and then her husband, Jerry, both to cancer. Several months after Jerry’s death, she decided to make one small change in her life - she shut down his landline, which crashed her internet. She ended up in Verizon hell.

After years of struggling in a tumultuous marriage, writer Rebecca Woolf was finally ready to leave her husband. Two weeks after telling him she wanted a divorce, he was diagnosed with stage four pancreatic cancer. Four months later, at the age of forty-four, he died. In All of This, Woolf chronicles the months before her husband’s death—and her rebirth after he was gone. With rigorous honesty and incredible awareness, she reflects on the end of her marriage: how her husband’s illness finally gave her the space to make peace with his humanity and her own.

In Shock is a riveting first-hand account from a young critical care physician, who in the passage of a moment is transfigured into a dying patient. This transposition, coincidentally timed at the end of her medical training, instantly lays bare the vast chasm between the conventional practice of medicine and the stark reality of the prostrate patient.

In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

Sarah Standing is a wife, a mother, a journalist, a toy shop owner, a grandmother, a great friend, a daughter, and a lover of life. She does not have the time, or inclination, to deal with cancer. But s--t happens. After a week or two of struggling to catch her breath, Sarah pops along to see her GP for a few tests. By the end of the day, she has a bag of what looks like bone broth draining from her body and is dealing with a diagnosis of non-Hodgkins lymphoma. It's cancer, says her doctor, but it's the good kind.

A powerful memoir from the Saturday Night Live cast member Cecily Strong about grieving the death of her cousin - and embracing the life-affirming lessons he taught her - amid the coronavirus pandemic.

Laurie Zaleski never aspired to run an animal rescue; that was her mother Annie’s dream. But from girlhood, Laurie was determined to make the dream come true. Thirty years later as a successful businesswoman, she did it, buying a 15-acre farm deep in the Pinelands of South Jersey. She was planning to relocate Annie and her caravan of ragtag rescues - horses and goats, dogs and cats, chickens and pigs - when Annie died, just two weeks before moving day. In her heartbreak, Laurie resolved to make her mother’s dream her own.

In this wryly humorous and innovative look at a marriage gone wrong, Hannah Pittard recalls a decade’s worth of unforgettable conversations, beginning with the one in which she discovers her husband has been having sex with her charismatic best friend, Trish. These time-jumping exchanges are fast-paced, intimate, and often jaw-dropping in their willingness to reveal the vulnerabilities inherent in any friendship or marriage.

In the tradition of books by such bestselling physician-authors as Atul Gawande, Siddhartha Mukherjee, and Danielle Ofri, this beautifully written memoir by an emergency room doctor takes place during one of his routine shifts at an urban ER. Intimately narrated as it follows the experiences of real patients, it is filled with fascinating, adrenaline-pumping scenes of rescues and deaths, and the critical, often excruciating follow-through in caring for the patients’ families.

Barbara Butcher was early in her recovery from alcoholism when she found an unexpected lifeline: a job at the Medical Examiner’s Office in New York City. The second woman ever hired for the role of Death Investigator in Manhattan, she was the first to last more than three months. The work was gritty, demanding, morbid, and sometimes dangerous—and she loved it. In What the Dead Know, she writes with the kind of New York attitude and bravado you might expect from decades in the field, investigating more than 5,500 death scenes, 680 of which were homicides.

Despite her training and years of experience as an oncology and hospice nurse, Brown finds it difficult to navigate the medical maze from the other side of the bed. Why is she so often left in the dark about procedures and treatments? Why is she expected to research her own best treatment options? Why is there so much red tape? At times she’s mad at herself for not speaking up and asking for what she needs but knows that being a “difficult” patient could mean she gets worse care.

One afternoon, Emma Nadler gets a call from her daughter's doctor that changes her life forever. Faced with the realities of raising a child with a rare genetic condition, Nadler must confront her preconceptions of motherhood and her perfectionistic beliefs. Nadler—who also happens to be a psychotherapist—offers a rare window into the unconventional ways she and her family adapt to their improbable path. Every relationship in her life—with herself, her husband, children, friends, and even clients—is reimagined as she navigates the heartbreak and hilarity of her daily life.

In 2016, Rob Delaney’s one-year-old son, Henry, was diagnosed with a brain tumor. The family had moved from Los Angeles to London with their two young boys when Rob’s wife was pregnant with Henry, their third. The move was an adventure that would bind them even more tightly together as they navigated the novelty of London, the culture clashes, and the funhouse experience of Rob’s fame—thanks to his role as co-creator and co-star of the hit series Catastrophe. Henry’s illness was a cataclysm that changed everything about their lives.

One morning in late 2017, New York Times columnist Frank Bruni woke up with strangely blurred vision. He wondered at first if some goo or gunk had worked its way into his right eye. But this was no fleeting annoyance, no fixable inconvenience.