Dr. Jonathan Reisman - a physician, adventure traveler, and naturalist - brings listeners on an odyssey, navigating our insides like an explorer discovering a new world. With unique insight, Reisman shows us how understanding mountain watersheds helps to diagnose heart attacks, how the body is made mostly of mucus, not water, and how urine carries within it a tale of humanity’s origins.

In the early 1960s, JFK declared that science would take us to the moon. He also declared that science would make the “remote reaches of the mind accessible” and cure psychiatric illness with breakthrough medications. We were walking on the moon within the decade. But today, psychiatric cures continue to elude us—as does the mind itself. Why is it that we still don’t understand how the mind works? What is the difference between the mind and the brain? And given all that we still don’t know, how can we make insightful, transformative choices about our psychiatric conditions?

After Jim O’Connell graduated from Harvard Medical School and was nearing the end of his residency at Massachusetts General, the hospital’s chief of medicine made a proposal: Would he defer a prestigious fellowship and spend a year helping to create an organization to bring health care to homeless citizens? That year turned into O’Connell’s life’s calling. Tracy Kidder spent five years following Dr. O’Connell and his colleagues as they work with thousands of homeless patients, some of whom we meet in this illuminating book.

Wallace Stegner's uniquely American classic centers on Lyman Ward, a noted historian who relates a fictionalized biography of his pioneer grandparents at a time when he has become estranged from his own family. Through a combination of research, memory, and exaggeration, Ward voices ideas concerning the relationship between history and the present, art and life, parents and children, and husbands and wives.

On April 6, 1965, Georges Lemay was relaxing on his yacht in a south Florida marina following one of the largest and most daring bank heists in Canadian history. For four years, the roguishly handsome criminal mastermind hid in plain sight, eluding capture and the combined efforts of the FBI, Interpol, and the Royal Canadian Mounted Police. His future appeared secure. What Lemay didn't know was that less than two hundred miles away at Cape Canaveral, a brilliant engineer named Harold Rosen was about to usher in the age of global live television.

From NBA legend Bill Russell, Go Up for Glory is a basketball memoir that transcends time. First published in 1965, this narrative traces Russell's childhood in segregated America and details the challenges he faced as a Black man, even when he was a celebrated NBA star. And while some progress has been made, this book serves as an urgent reminder of how far we still have to go in the fight for human rights and equality.

For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.

You Can’t Be Serious is a series of funny, consequential, awkward, and ridiculous stories from Kal Penn’s idiosyncratic life. It’s about being the grandson of Gandhian freedom fighters, and the son of immigrant parents: people who came to this country with very little and went very far—and whose vision of the American dream probably never included their son sliding off an oiled-up naked woman in the raunchy Ryan Reynolds movie Van Wilder…or getting a phone call from Air Force One as Kal flew with the country’s first Black president.

Moscow, Christmas Eve, 1949. The Soviet secret police intercept a call made to the American embassy by a Russian diplomat who promises to deliver secrets about the nascent Soviet Atomic Bomb program. On that same day, a brilliant mathematician is locked away inside a Moscow prison that houses the country's brightest minds. He and his fellow prisoners are charged with using their abilities to sleuth out the caller's identity, and they must choose whether to aid Joseph Stalin's repressive state - or refuse and accept transfer to the Siberian Gulag camps, and almost certain death.

When you listen to music, do you prefer lyrics or melody? Intricate harmonies or driving rhythm? The “real” sounds of acoustic instruments or those of computerized synthesizers? Drawing from her successful career as a music producer (engineering hits like Prince’s “Purple Rain”), professor of cognitive neuroscience Susan Rogers reveals why your favorite songs move you. She explains that we each possess a unique “listener profile” based on our brain’s reaction to seven key dimensions of any record: authenticity, realism, novelty, melody, lyrics, rhythm, and timbre.

The unforgettable, inspiring story of a teenage girl growing up in a rural Nigerian village who longs to get an education so that she can find her “louding voice” and speak up for herself, The Girl with the Louding Voice is a simultaneously heartbreaking and triumphant tale about the power of fighting for your dreams.

Hollywood Park is a remarkable memoir of a tumultuous life. Mikel Jollett was born into one of the country’s most infamous cults and subjected to a childhood filled with poverty, addiction, and emotional abuse. Yet, ultimately, his is a story of fierce love and family loyalty told in a raw, poetic voice that signals the emergence of a uniquely gifted writer.

Sam Hill always saw the world through different eyes. Born with red pupils, he was called “Devil Boy” or Sam “Hell” by his classmates; “God’s will” is what his mother called his ocular albinism. Her words were of little comfort, but Sam persevered. Sam believed it was God who sent Ernie Cantwell, the only African American kid in his class, to be the friend he so desperately needed. And that it was God’s idea for Mickie Kennedy to storm into Our Lady of Mercy like a tornado, uprooting every rule Sam had been taught about boys and girls. Forty years later, Sam, a small-town eye doctor, is no longer certain anything was by design.

Best-selling author and Sundance award-winning director Questlove harnesses his encyclopedic knowledge of popular music and his deep curiosity about history to examine America over the past 50 years. Choosing one essential track from each year, Questlove unpacks each song’s significance, revealing the pivotal role that American music plays around issues of race, gender, politics, and identity.

At the front of a middle-school classroom in Oklahoma, a boy named Khosrou (whom everyone calls "Daniel") stands, trying to tell a story. His story. But no one believes a word he says. To them he is a dark-skinned, hairy-armed boy with a big butt whose lunch smells funny; who makes things up and talks about poop too much.

The author of Break in Case of Emergency follows up her the “extraordinary debut” (The Guardian) with a moving novel about motherhood and marriage, adolescence and bodily autonomy, family and love, religion and sexuality, and the delicate balance between the purity of faith and the messy reality of life.

Lone Stars follows the arc of four generations of a Texan family in a changing America. Julian Warner, a father at last, wrestles with a question his husband posed: what will you tell our son about the people you came from, now that they're gone? Finding the answers takes Julian back in time to Eisenhower's immigration border raids, an epistolary love affair during the Vietnam War, crumbling marriages, queer migrations to Cambridge and New York, up to the disorienting polarization of Obama's second term.

Mitchell S. Jackson grew up black in a neglected neighborhood in America’s whitest city, Portland, Oregon. In the ’90s, those streets and beyond had fallen under the shadow of crack cocaine and its familiar mayhem. In his commanding autobiographical novel, Mitchell writes what it was to come of age in that time and place, with a break-out voice that’s nothing less than extraordinary. The Residue Years switches between the perspectives of a young man, Champ, and his mother, Grace.

Born to a poor couple who were tenant farmers on a plantation in Mississippi, Anne Moody lived through some of the most dangerous days of the pre-civil rights era in the South. The week before she began high school came the news of Emmet Till's lynching. Before then, she had "known the fear of hunger, hell, and the Devil. But now there was…the fear of being killed just because I was black." In that moment was born the passion for freedom and justice that would change her life.

Fifty-five years ago, in 1964, an incredibly honest and revealing memoir by one of the America's best-loved comedians and activists, Dick Gregory, was published. With a shocking title and breathtaking writing, Dick Gregory defined a genre and changed the way race was discussed in America.

Del has had a crush on Kiera Westing since kindergarten. And now, during their junior year, she’s finally available. So when Kiera volunteers for an opportunity at their church, Del’s right behind her. Though he quickly realizes he’s inadvertently signed up for a Purity Pledge. His dad thinks his wires are crossed, and his best friend, Qwan, doesn’t believe any girl is worth the long game. But Del’s not about to lose his dream girl, and that’s where fellow pledger Jameer comes in.

Scars and Stilettos: At 13, after being abandoned by her mother one summer and left to take care of her younger brother, Harmony becomes susceptible to a relationship that turns out to be toxic, abusive, and ultimately exploitative. She eventually finds herself working in a strip club at the age of 19, and her boyfriend becomes her pimp, controlling her every move and taking all of her money. Ultimately, she discovers a path to freedom and a whole new life.

Mishna Wolff grew up in a poor black neighborhood with her single father, a white man who truly believed he was black. "He strutted around with a short perm, a Cosby-esque sweater, gold chains and a Kangol---telling jokes like Redd Fox, and giving advice like Jesse Jackson. You couldn't tell my father he was white. Believe me, I tried," writes Wolff. And so from early childhood on, her father began his crusade to make his white daughter down.

Problem Child is the unbelievably true story of Terrell Carter, an American musician and actor who grew up in Buffalo, New York, in a dysfunctional family, each member crazier than the next. And the Problem Child is the only one in the story who may, or may not, actually have a problem. An emotional journey of trials and revelations, with a huge secret at its core, this story may force you to laugh - just to keep from crying.

Jasmine and Chelsea are best friends on a mission - they’re sick of the way women are treated even at their progressive NYC high school, so they decide to start a Women's Rights Club. They post their work online - poems, essays, videos of Chelsea performing her poetry, and Jasmine's response to the racial microaggressions she experiences - and soon go viral. But with such positive support, the club is also targeted by trolls. When things escalate, the principal shuts the club down. Not willing to be silenced, Jasmine and Chelsea will risk everything for their voices to be heard.