Spanning the years 1900 to 1977, The Covenant of Water is set in Kerala, on South India’s Malabar Coast, and follows three generations of a family that suffers a peculiar affliction: in every generation, at least one person dies by drowning—and in Kerala, water is everywhere. At the turn of the century, a twelve-year-old girl from Kerala’s long-existing Christian community, grieving the death of her father, is sent by boat to her wedding, where she will meet her forty-year-old husband for the first time.

Amy Bloom began to notice changes in her husband, Brian: He retired early from a new job he loved; he withdrew from close friendships; he talked mostly about the past. Suddenly, it seemed there was a glass wall between them, and their long walks and talks stopped. Their world was altered forever when an MRI confirmed what they could no longer ignore: Brian had Alzheimer’s disease.

In the tradition of books by such bestselling physician-authors as Atul Gawande, Siddhartha Mukherjee, and Danielle Ofri, this beautifully written memoir by an emergency room doctor takes place during one of his routine shifts at an urban ER. Intimately narrated as it follows the experiences of real patients, it is filled with fascinating, adrenaline-pumping scenes of rescues and deaths, and the critical, often excruciating follow-through in caring for the patients’ families.

Offering examples of how to make medicine better for the healers and those they serve, If I Betray These Words profiles clinicians across the country who are tough, resourceful, and resilient, but feel trapped between the patient-first values of their Hippocratic oath and the business imperatives of a broken healthcare system. If I Betray These Words confronts the threat and broken promises of moral injury—what it is; where it comes from; how it manifests; and who’s fighting back against it. We need better healthcare—for patients and for the workforce. It’s time to act.

Chemist Elizabeth Zott is not your average woman. In fact, Elizabeth Zott would be the first to point out that there is no such thing as an average woman. But it’s the early 1960s and her all-male team at Hastings Research Institute takes a very unscientific view of equality. Except for one: Calvin Evans; the lonely, brilliant, Nobel–prize nominated grudge-holder who falls in love with—of all things—her mind. True chemistry results.

It was one of the most searing images of the twentieth century: two young boys, two princes, walking behind their mother’s coffin as the world watched in sorrow—and horror. As Princess Diana was laid to rest, billions wondered what Prince William and Prince Harry must be thinking and feeling—and how their lives would play out from that point on.

Set in the mountains of southern Appalachia, Demon Copperhead is the story of a boy born to a teenaged single mother in a single-wide trailer, with no assets beyond his dead father’s good looks and copper-colored hair, a caustic wit, and a fierce talent for survival. Relayed in his own unsparing voice, Demon braves the modern perils of foster care, child labor, derelict schools, athletic success, addiction, disastrous loves, and crushing losses.

Growing up gifted and working-class poor in the foothills of the Ozarks, Monica and Darci became fast friends. The girls bonded over a shared love of reading and learning, even as they navigated the challenges of their declining town and tumultuous family lives—broken marriages, alcohol abuse, and shuttered stores and factories. They pored over the giant map in their middle school classroom, tracing their fingers over the world that awaited them, vowing to escape. In the end, Monica left Clinton for college and fulfilled her dreams; Darci did not.

As a retired brain surgeon, Henry Marsh thought he understood illness, but he was unprepared for the impact of his diagnosis of advanced cancer. And Finally explores what happens when someone who has spent a lifetime on the frontline of life and death finds himself contemplating what might be his own death sentence. As he navigates the bewildering transition from doctor to patient, he is haunted by past failures and projects yet to be completed, and frustrated by the inconveniences of illness and old age.

Talking about death and dying is considered taboo in polite company, and even in the medical field. Our ideas about dying are confusing at best: Will our memories flash before our eyes? Regrets consume our thoughts? Does a bright light appear at the end of a tunnel? For most people, it will be a slower process, one eased with preparedness, good humor, and a bit of faith. At the forefront of changing attitudes around palliative care is hospice nurse Hadley Vlahos, who shows that end-of-life care can teach us just as much about how to live as it does about how we die.

Tumors, injuries, ruptured vascular malformations—there is almost no such thing as a non-urgent brain surgery when it comes to kids. For a pediatric neurosurgeon working in the medical minefield of the brain—in which a single millimeter in every direction governs something that makes us essentially human—every day presents the challenge, and the opportunity, to give a new lease on life to a child for whom nothing is yet fully determined and all possibilities still exist.

William Waters grew up in a house silenced by tragedy, where his parents could hardly bear to look at him, much less love him—so when he meets the spirited and ambitious Julia Padavano in his freshman year of college, it’s as if the world has lit up around him. With Julia comes her family, as she and her three sisters are inseparable: Sylvie, the family’s dreamer, is happiest with her nose in a book; Cecelia is a free-spirited artist; and Emeline patiently takes care of them all.

With all his family and friends gone except an estranged grandson, retired Major League ballplayer Murray McBride is looking for a reason to live. He finds it in Jason Cashman, a spirited 10-year-old boy with a terminal heart defect and a list of five things he wants to do before he dies. Murray is determined to help Jason fulfill his dreams. Together, they race against the limited time each has left, ticking off Jason's wishes one by one.

On October 22, 1989, in the small town of St. Joseph, Minnesota, eleven-year-old Jacob Wetterling was kidnapped at gunpoint. Twenty-seven years later, Danny Heinrich led authorities to the boy’s remains. What lies between is the riveting story of the search for Jacob, told by his mother, Patty. With down-to-earth candor, she details the investigation as it unfolds, discusses her family’s struggles, and shows how she maintained her energy and optimism.

In the summer after graduating from college, Suleika Jaouad was preparing, as they say in commencement speeches, to enter “the real world”. She had fallen in love and moved to Paris to pursue her dream of becoming a war correspondent. The real world she found, however, would take her into a very different kind of conflict zone. It started with an itch - first on her feet, then up her legs, like a thousand invisible mosquito bites. Then a trip to the doctor and, a few weeks shy of her 23rd birthday, a diagnosis: leukemia, with a 35 percent chance of survival.