Inside the O'Briens
A Novel
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Narrated by:
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Skipp Sudduth
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By:
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Lisa Genova
About this listen
From award-winning, New York Times best-selling author Lisa Genova comes a powerful new novel that does for Huntington's disease what her debut Still Alice did for Alzheimer's.
Joe O'Brien is a 44-year-old Boston police officer from the Irish Catholic neighborhood of Charlestown, Massachusetts. A devoted husband, a proud father of four children in their 20s, and a respected, seasoned law enforcement officer, Joe begins experiencing bouts of disorganized thinking, uncharacteristic temper outbursts, and strange, involuntary movements. He initially attributes these episodes to aging and the cumulative physical and psychological stress of his job, but as these symptoms worsen, he agrees to see a neurologist and is handed a diagnosis that will change his and his family's lives forever: Huntington's disease.
Huntington's is a lethal neurodegenerative disease with no treatment and no cure. And it is genetic. Each of Joe's four children has a 50 percent chance of inheriting their father's disease, and a simple blood test can reveal their genetic fate. While watching their potential futures in their father's escalating symptoms, the children struggle with the questions this test imposes on their young adult lives, including his youngest, 21-year-old Katie. Does she want to know? What if she's gene positive? Can she live with the constant anxiety of not knowing?
As Joe's symptoms worsen, and he's eventually stripped of his badge and more, he struggles to maintain his identity and sense of purpose. How can he find hope in a situation that feels hopeless? How can he find courage without any armor or weapons? What else might he be able to pass down to his children other than a fatal disease? Where is the honor in living and dying with Huntington's?
©2015 Lisa Genova (P)2015 Simon & SchusterListeners also enjoyed...
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The narrator's performance made the difference.
- By KT on 06-11-15
By: Angela Flournoy
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Love Walked In
- By: Marisa de los Santos
- Narrated by: Jennifer Ikeda
- Length: 11 hrs and 40 mins
- Unabridged
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Award-winning poet Marisa de los Santos crafts an irresistibly touching debut novel. Love Walked In is a contemporary tale, steeped in nostalgic, cinematic charm, of love in all its forms. Unapologetically idealistic about love, Cornelia Brown appears to catch the break of a lifetime when the dashing Martin Grace, her own personal Cary Grant, comes strolling into her life. But it is Martin's connection to 11-year-old Clare Hobbes that touches Cornelia's heart in ways she never imagined.
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Dreadful audio quality
- By Marenghi on 09-16-11
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The Hour I First Believed
- A Novel
- By: Wally Lamb
- Narrated by: George Guidall
- Length: 25 hrs and 9 mins
- Unabridged
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Story
When high-school teacher Caelum Quirk and his wife, Maureen, move to Littleton, Colorado, they both get jobs at Columbine High School. In April 1999, while Caelum is away, Maureen finds herself in the library at Columbine, cowering in a cabinet and expecting to be killed. Miraculously, she survives. But when Caelum and Maureen flee to an illusion of safety on the Quirk family's Connecticut farm, they discover that the effects of chaos are not easily put right.
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excellent all around yarn
- By G. on 01-10-09
By: Wally Lamb
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If I am Missing or Dead
- A Sister's Story of Love, Murder, and Liberation
- By: Janine Latus
- Narrated by: Shelly Frasier
- Length: 8 hrs and 53 mins
- Unabridged
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In April 2002, Janine Latus' youngest sister, Amy, wrote a note and taped it to the inside of her desk drawer. "Today Ron Ball and I are romantically involved", it read, "but I fear I have placed myself at risk in a variety of ways. Based on his criminal past, writing this out just seems like the smart thing to do. If I am missing or dead this obviously has not protected me...."
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All About Janine
- By Ellen on 07-02-07
By: Janine Latus
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Pushing the Limits
- By: Katie McGarry
- Narrated by: MacLeod Andrews, Tara Sands
- Length: 11 hrs
- Unabridged
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Story
No one knows what happened the night Echo Emerson went from popular girl with jock boyfriend to gossiped-about outsider with "freaky" scars on her arms. Even Echo can't remember the whole truth of that horrible night. All she knows is that she wants everything to go back to normal. But when Noah Hutchins, the smoking-hot, girl-using loner in the black leather jacket, explodes into her life with his tough attitude and surprising understanding, Echo's world shifts in ways she could never have imagined. They should have nothing in common. And with the secrets they both keep, being together is pretty much impossible....
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The Tough Stuff.
- By Bee on 09-12-12
By: Katie McGarry
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The Life List
- A Novel
- By: Lori Nelson Spielman
- Narrated by: Rebecca Gibel
- Length: 11 hrs and 33 mins
- Unabridged
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Story
Brett Bohlinger has forgotten all about the list of life goals she’d written as a naïve teenager. In fact, at 34, Brett seems to have it all—a plum job at her family’s multimillion-dollar company and a spacious loft with her irresistibly handsome boyfriend. But when her beloved mother, Elizabeth, passes away, Brett’s world is turned upside down. Rather than simply naming her daughter the new CEO of Bohlinger Cosmetics, Elizabeth’s will comes with one big stipulation: Brett must fulfill the list of childhood dreams she made so long ago.
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Truly Terrible.
- By Cricket on 04-27-14
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Marrow
- By: Tarryn Fisher
- Narrated by: Audra Pagano
- Length: 10 hrs and 7 mins
- Unabridged
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Story
Margo is not like other girls. She lives in a derelict neighborhood called the Bone, in a cursed house, with her cursed mother, who hasn't spoken to her in over two years. She lives her days feeling invisible. It's not until she develops a friendship with her wheelchair-bound neighbor, Judah Grant, that things begin to change. When a neighborhood girl, seven-year-old Neveah Anthony, goes missing, Judah sets out to help Margo uncover what happened to her. What Margo finds changes her, and with a new perspective on life she's determined to find evil and punish it.
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HUH?? I'm so confused LOL
- By ❤️Cyndi Marie❤️🎧Audiobook Addicts🎧 on 09-15-16
By: Tarryn Fisher
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Side Effects May Vary
- By: Julie Murphy
- Narrated by: Cassandra Campbell, Kirby Heyborne
- Length: 9 hrs and 16 mins
- Unabridged
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Overall
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Performance
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Story
When 16-year-old Alice is diagnosed with leukemia, her prognosis is grim. To maximize the time she does have, she vows to spend her final months righting wrongs - however she sees fit. She convinces her friend Harvey, who she knows has always had feelings for her, to help her with a crazy bucket list that's as much about revenge (humiliating her ex-boyfriend and getting back at her archnemesis) as it is about hope (doing something unexpectedly kind for a stranger).
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Listening Experiences May Vary
- By The Reading Date on 05-18-14
By: Julie Murphy
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Leaving Paradise, Book 1
- By: Simone Elkeles
- Narrated by: Nick Mondelli
- Length: 7 hrs and 10 mins
- Unabridged
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Performance
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Story
Nothing has been the same since Caleb Becker left a party drunk, got behind the wheel, and hit Maggie Armstrong. Even after months of painful physical therapy, Maggie walks with a limp. Her social life is nil and a scholarship to study abroad - her chance to escape everyone and their pitying stares - has been canceled. After a year in juvenile jail, Caleb’s free...if freedom means endless nagging from a transition coach and the prying eyes of the entire town. Coming home should feel good, but his family and ex-girlfriend seem like strangers.
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Couldnt finish so bad
- By Chelsea on 09-11-18
By: Simone Elkeles
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Beautiful Addictions
- By: Season Vining
- Narrated by: Susannah Jones
- Length: 8 hrs and 53 mins
- Unabridged
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Performance
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Story
Josie Banks is a girl without a past. After being found unconscious with no memory, she was shuffled in and out of foster homes where she suffered years of abuse - an experience that left her broken, damaged, and clinging to drugs and meaningless hook-ups to numb her pain. When Josie disappeared years ago, she took a piece of Tristan with her. She’s the girl he thought he lost forever - the one he’s never been able to forget. Now a twist of fate has brought them back together, and he never wants to let her out of his inked arms again.
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you will feel so many emotions threw out this book
- By sydney on 06-12-14
By: Season Vining
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The Opportunist
- By: Tarryn Fisher
- Narrated by: Andi Arndt
- Length: 8 hrs and 2 mins
- Unabridged
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Story
Olivia Kaspen has just discovered that her ex-boyfriend Caleb Drake has lost his memory. With an already lousy reputation for taking advantage of situations, Olivia must decide how far she is willing to go to get Caleb back.
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overall: irritating book
- By DD on 02-14-17
By: Tarryn Fisher
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The Real Enemy
- Sophie Trace Trilogy, Book 1
- By: Kathy Herman
- Narrated by: Tim Lundeen
- Length: 9 hrs and 10 mins
- Unabridged
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Overall
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Performance
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Story
Brill Jessup just became the first female police chief in Sophie Trace, Tennessee, and is riding on the credentials of a stellar 18-year career on the Memphis police force. She may be a pro at finding clues, but she tends to ignore the obvious in her personal life. Her husband, Kurt, is weighed down by her unrelenting anger as he struggles to let God redeem the stupidest mistake he ever made.
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Glad it's a Series!
- By Martha on 11-05-12
By: Kathy Herman
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Still Missing
- By: Chevy Stevens
- Narrated by: Angela Dawe
- Length: 9 hrs and 6 mins
- Unabridged
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Overall
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Performance
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Story
On the day she was abducted, Annie O’Sullivan, a 32-year-old Realtor, had three goals: sell a house, forget about a recent argument with her mother, and be on time for dinner with her ever-patient boyfriend. The open house is slow, but when her last visitor pulls up in a van as she’s about to leave, Annie thinks it just might be her lucky day after all.
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A singular voice; a horrendous story.
- By Richard Delman on 01-21-12
By: Chevy Stevens
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Not what I expected.
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Remember
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In Remember, neuroscientist and acclaimed novelist Lisa Genova delves into how memories are made and how we retrieve them. You'll learn whether forgotten memories are temporarily inaccessible or erased forever and why some memories are built to exist for only a few seconds (like a passcode) while others can last a lifetime (your wedding day). You'll come to appreciate the clear distinction between normal forgetting (where you parked your car) and forgetting due to Alzheimer's (that you own a car).
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Alice Howland is proud of the life she worked so hard to build. At 50 years old, she's a cognitive psychology professor at Harvard and a world-renowned expert in linguistics with a successful husband and three grown children. When she begins to grow disoriented and forgetful, a tragic diagnosis changes her life - and her relationship with her family and the world - forever.
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Please pay for a professional Reader
- By sunstan on 12-07-14
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From neuroscientist and New York Times bestselling author of Still Alice comes a powerful and heartbreaking exploration of regret, forgiveness, freedom, and what it means to be alive.
An accomplished concert pianist, Richard received standing ovations from audiences all over the world in awe of his rare combination of emotional resonance and flawless technique. Every finger of his hands was a finely calibrated instrument, dancing across the keys and striking each note with exacting precision. That was eight months ago.
Richard now has ALS, and his entire right arm is paralyzed. His fingers are impotent, still, devoid of possibility. The loss of his hand feels like a death, a loss of true love, a divorce—his divorce.
He knows his left arm will go next.
Three years ago, Karina removed their framed wedding picture from the living room wall and hung a mirror there instead. But she still hasn’t moved on. Karina is paralyzed by excuses and fear, stuck in an unfulfilling life as a piano teacher, afraid to pursue the path she abandoned as a young woman, blaming Richard and their failed marriage for all of it.
When Richard becomes increasingly paralyzed and is no longer able to live on his own, Karina becomes his reluctant caretaker. As Richard’s muscles, voice, and breath fade, both he and Karina try to reconcile their past before it’s too late.
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Maddy Banks is just like any other stressed-out freshman at NYU. Between schoolwork, exams, navigating life in the city, and a recent breakup, it’s normal to be feeling overwhelmed. It doesn’t help that she’s always felt like the odd one out in her picture-perfect Connecticut family. But Maddy’s latest low is devastatingly low, and she goes on an antidepressant. She begins to feel good, dazzling in fact, and she soon spirals high into a wild and terrifying mania that culminates in a diagnosis of bipolar disorder.
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What listeners say about Inside the O'Briens
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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Performance
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- Susan Lawson
- 04-18-16
Learned A Lot
Even though it can be sad it was uplifting and informative
I absolutely recommend it
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1 person found this helpful
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- Lucinda Parsons
- 09-19-15
Educational and entertaining
The characters are all fully developed and interesting. They're people I can relate to. Many points in the story that brought tears and many that made me laugh out loud.
Highly recommended.
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- Amy M Brookes
- 03-19-18
pretty good overall...but
The indecision of one character was maddening, and I didn't agree with the ethical decisions by some of the characters.
Overall, it was engaging, though, just a few hiccups through the indecision phase. The ending wasn't awesome (or at least according to me, some might like it, apparently the author did).
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- Nicole M. Lattimore
- 06-23-17
Great but then left questioning
I enjoyed this book and completely gave you a better at clinical understanding of Huntington's disease but I do not like how the author ended the book and anticipation for what's next I don't know if Katie has it or if she didn't I would like to know more
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- B.S.Johnston
- 04-03-23
Lisa Genova heartbreaker
Every book she writes educates you, but it also makes you more human when confronted with or by anyone who is going through this. However, since this one covers multiple generations, it was a real tearjerker for me.
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- Stephanie B. Manis
- 05-02-15
Good but
I really liked the book. However, I did not approve of the author's ending.
I thought it needed to carry the individual stories further along.
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5 people found this helpful
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- jessica
- 05-24-16
Amazing!
Another amazing book by Genova! love the medical combination with a great story! very well written!
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1 person found this helpful
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- Giorgia Johnson
- 04-20-16
Engaging story, fabulous performance
Loved the performance, it bought a surprising warmth and immediacy to Lisa Genova s fascinating tale of how different family members deal with learning about their hereditary and fatal condition
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1 person found this helpful
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- Amazon Customer
- 05-09-16
Couldn't stop listening
Great story, loved the narrator. Wish it had gone on longer, since I got so attached to the characters.
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1 person found this helpful
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- Carolyn
- 04-25-15
An unforgettable education about Huntingtons
A powerful look at how this disease wreaks havoc on a family. But more importantly, a story of a family's love and spirit in the face of unimaginable fear of a future with Huntingtons. Sad but uplifting and Worth the read!
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