Chemist Elizabeth Zott is not your average woman. In fact, Elizabeth Zott would be the first to point out that there is no such thing as an average woman. But it’s the early 1960s and her all-male team at Hastings Research Institute takes a very unscientific view of equality. Except for one: Calvin Evans; the lonely, brilliant, Nobel–prize nominated grudge-holder who falls in love with—of all things—her mind. True chemistry results.

In June, 1954, eighteen-year-old Emmett Watson is driven home to Nebraska by the warden of the juvenile work farm where he has just served fifteen months for involuntary manslaughter. His mother long gone, his father recently deceased, and the family farm foreclosed upon by the bank, Emmett's intention is to pick up his eight-year-old brother, Billy, and head to California where they can start their lives anew. But when the warden drives away, Emmett discovers that two friends from the work farm have hidden themselves in the trunk of the warden's car.

Kentucky, 1850. An enslaved groom named Jarret and a bay foal forge a bond of understanding that will carry the horse to record-setting victories across the South. When the nation erupts in civil war, an itinerant young artist who has made his name on paintings of the racehorse takes up arms for the Union. On a perilous night, he reunites with the stallion and his groom, very far from the glamor of any racetrack.

Colombo, 1990. Maali Almeida—war photographer, gambler, and closet queen—has woken up dead in what seems like a celestial visa office. His dismembered body is sinking in the serene Beira Lake and he has no idea who killed him. In a country where scores are settled by death squads, suicide bombers, and hired goons, the list of suspects is depressingly long, as the ghouls and ghosts with grudges who cluster round can attest. But even in the afterlife, time is running out for Maali.

In her twenties, Belle da Costa Greene is hired by J. P. Morgan to curate a collection of rare manuscripts, books, and artwork for his newly built Pierpont Morgan Library. Belle becomes a fixture in New York City society and one of the most powerful people in the art and book world, known for her impeccable taste and shrewd negotiating for critical works as she helps create a world-class collection.

Boston, 1662. Mary Deerfield is 24 years old. Her skin is porcelain, her eyes delft blue, and in England she might have had many suitors. But here in the New World, amid this community of saints, Mary is the second wife of Thomas Deerfield, a man as cruel as he is powerful. When Thomas, prone to drunken rage, drives a three-tined fork into the back of Mary's hand, she resolves that she must divorce him to save her life.

Based on the extraordinary life of National Book Award-winning author Louise Erdrich’s grandfather who worked as a night watchman and carried the fight against Native dispossession from rural North Dakota all the way to Washington, DC, this powerful novel explores themes of love and death with lightness and gravity and unfolds with the elegant prose, sly humor, and depth of feeling of a master craftsman.

Woodrow Wilson Nickel, age 105, feels his life ebbing away. But when he learns giraffes are going extinct, he finds himself recalling the unforgettable experience he cannot take to his grave. It’s 1938. The Great Depression lingers. Hitler is threatening Europe, and world-weary Americans long for wonder. They find it in two giraffes who miraculously survive a hurricane while crossing the Atlantic. What follows is a twelve-day road trip in a custom truck to become Southern California’s first giraffes. Behind the wheel is the young Dust Bowl rowdy Woodrow.

In a remote Polish village, Janina devotes the dark winter days to studying astrology, translating the poetry of William Blake, and taking care of the summer homes of wealthy Warsaw residents. Her reputation as a crank and a recluse is amplified by her not-so-secret preference for the company of animals over humans. Then, a neighbor, Big Foot, turns up dead. Soon, other bodies are discovered, in increasingly strange circumstances. As suspicions mount, Janina inserts herself into the investigation, certain that she knows whodunit. If only anyone would pay her mind....

Chief Inspector Armand Gamache of the Surêté du Québec and his team of investigators are called in to the scene of a suspicious death in a rural village south of Montreal. Jane Neal, a local fixture in the tiny hamlet of Three Pines, just north of the U.S. border, has been found dead in the woods. The locals are certain it’s a tragic hunting accident and nothing more, but Gamache smells something foul in these remote woods, and is soon certain that Jane Neal died at the hands of someone much more sinister than a careless bowhunter.

It is 1950. London is still reeling from World War II, and Margery Benson, a schoolteacher and spinster, is trying to get through life, surviving on scraps. One day, she reaches her breaking point, abandoning her job and small existence to set out on an expedition to the other side of the world in search of her childhood obsession: an insect that may or may not exist - the golden beetle of New Caledonia. When she advertises for an assistant to accompany her, the woman she ends up with is the last person she had in mind.

To his customers and neighbors on 125th street, Ray Carney is an upstanding salesman of reasonably priced furniture, making a decent life for himself and his family. He and his wife Elizabeth are expecting their second child, and if her parents on Striver's Row don't approve of him or their cramped apartment across from the subway tracks, it's still home. Few people know he descends from a line of uptown hoods and crooks, and that his façade of normalcy has more than a few cracks in it. Cracks that are getting bigger all the time.

Morayo Da Silva, a cosmopolitan Nigerian woman, lives in hip San Francisco. On the cusp of 75, she is in good health and makes the most of it, enjoying road trips in her vintage Porsche, chatting to strangers, and recollecting characters from her favorite novels. Then she has a fall and her independence crumbles. Without the support of family, she relies on friends and chance encounters.

After being rescued as infants from a sinking ocean liner in 1914, Marian and Jamie Graves are raised by their dissolute uncle in Missoula, Montana. There—after encountering a pair of barnstorming pilots passing through town in beat-up biplanes—Marian commences her lifelong love affair with flight. At fourteen she drops out of school and finds an unexpected and dangerous patron in a wealthy bootlegger who provides a plane and subsidizes her lessons, an arrangement that will haunt her for the rest of her life, even as it allows her to fulfill her destiny: circumnavigating the globe.

Nuri is a beekeeper and Afra, his wife, is an artist. Mornings, Nuri rises early to hear the call to prayer before driving to his hives in the countryside. On weekends, Afra sells her colorful landscape paintings at the open-air market. They live a simple life, rich in family and friends, in the hills of the beautiful Syrian city of Aleppo - until the unthinkable happens. When all they love is destroyed by war, Nuri knows they have no choice except to leave their home. But escaping Syria will be no easy task: Afra has lost her sight.