The first serious external threat to the mafia's existence in America comes from U.S. Attorney General Robert F. Kennedy, who repeatedly expresses his desire to eradicate organized crime in America. Kennedy unleashes the full force of the U.S. Justice Department to the apparent dismay of long-time FBI Director J. Edgar Hoover. The mafia's unforgiving response is executed by Louisiana don Carlos Marcello along with Florida don Santo Trafficante, who together take aim at the attorney general's brother, the president of the United States.

John Gotti was without a doubt the flashiest and most feared Mafioso in American history. He became the boss of the Gambino Crime Family in spectacular fashion—with the brazen and very public murder of Paul Castellano in front of Sparks Steakhouse in midtown Manhattan in 1985. Not one to stay below law enforcement’s radar, Gotti instead became the first celebrity crime boss. His penchant for eye-catching apparel earned him the nickname “The Dapper Don;” his ability to beat criminal charges led to another: “The Teflon Don.”

Widowed Blanche Taylor Moore was about to lose her second spouse to symptoms that mysteriously mirrored those that killed her first husband—as well as her previous boyfriend. When an investigation reveals arsenic poisoning, the hideous truth about the wife and mother comes to light. Did the abuse Blanche suffered as a child at the hands of her alcoholic father turn her into a murderer she became?

Elmer Wayne Henley, Jr. was only fourteen when he first became entangled with serial rapist and murderer Dean Corll in 1971. Fellow Houston, Texas, teenager David Brooks had already been ensnared by the charming older man, bribed with cash to help lure boys to Corll's home. Corll baited Henley with the same deal he'd given Brooks: $200 for each boy they could bring him.

For years, Eddie Lee Sexton ruled his large family like Charles Manson. The depraved patriarch dominated his ragged brood of twelve children mentally, physically, and sexually, and enforced every cruelty imaginable, from vicious beatings to raping his daughters and fathering their children. Finally, in 1992, Sexton's eighteen-year-old daughter Machelle, seeking refuge in a women's shelter, revealed the shocking, sordid details of her father's abuse to authorities. As the law attempted to catch up to Eddie Lee Sexton, he moved his family to a mobile home in western Florida.