Two little girls stand with their heads bowed in my living room. I’m told they’re my granddaughters. Daisy is nine, and Alice seven. Daisy is the spitting image of her mother. This is the first time I’ve met them since my daughter and I fell out after she married that waste of space, Vince. They’ve come to live with me because their mother — my daughter — was murdered. In her own home while they slept close by. I think Vince killed her. But the police can’t prove it. I’ve always known he was no good. He treated my daughter like dirt. I said he’d cheat on her — but she wouldn’t listen.

Lowen Ashleigh is a struggling writer on the brink of financial ruin when she accepts the job offer of a lifetime. Jeremy Crawford, husband of best-selling author Verity Crawford, has hired Lowen to complete the remaining books in a successful series his injured wife is unable to finish. Lowen arrives at the Crawford home, ready to sort through years of Verity's notes and outlines, hoping to find enough material to get her started. What Lowen doesn't expect to uncover in the chaotic office is an unfinished autobiography Verity never intended for anyone to read.

Who is Audrey Hoedemaker? It's a question her sister Maureen has heard more times than she can count, and she doesn't know what the short answer would be. Little sister, troubled teen, backpacker, musical theatre coach, con artist, childcare worker. Murderer. A tragic, traumatic childhood casts a long shadow on the Hoedemaker sisters. Maureen has worked hard to move beyond the violence of the past and build a good, honest life for herself. Audrey, however, just can't seem to do the same, careening from one state of chaos to another.

After the killing of a prominent mob lawyer, NYPD homicide detectives Jacob Jackson and Caitlin Grimes start receive chilling, written “rules” for how to commit the perfect murder. "Rule number one for the perfect murder: Evidence is your enemy. Leave none behind." Jackson (Reid Scott) and Grimes (Cobie Smulders) race to find the killer, setting them on a collision course with the city’s crime underbelly, and a perpetrator who seems happy to toy with them. “Rule number two. No crimes of passion. The perfect murder is always business, never pleasure.”

Kidnappers grabbed Jenna in broad daylight, right in front of her children and their horrified classmates. Her family was issued an insane ransom demand: $25 million in cash and jewels, payable by the end of the school day, otherwise they’ll never see her again. As Jenna’s mother scrambles to gather the money, detectives Mo Butler and George Ortega follow the trail of the kidnappers, which will lead them through a sordid landscape of jealous lovers, broken dreamers, and twisted schemers. But every second counts, and there’s one thing Jenna Wade doesn’t have: very much time.

No one called her Mud in Silicon Valley. There, she was Mae, a high-powered professional who had left her Kiowa roots behind a decade ago. But a cryptic voice message from her grandfather, James Sawpole, telling her to come home sounds so wrong that she catches the next plane to Oklahoma, where she finds a tribe in disarray. When Mud and her cousin Denny discover her grandfather missing, accused of stealing the valuable Jefferson Peace medal from the tribe museum—and stumble across a body in his work room—Mud has no choice but to search for answers.

Food anthropologist Miriam Quiñones-Smith's move from New York to Coral Shores, Miami, puts her academic career on hold to stay at home with her young son. Adding to her funk is an opinionated mother-in-law and a husband rekindling a friendship with his ex. Gracias to her best friend, Alma, she gets a short-term job as a Caribbean cooking expert on a Spanish-language morning TV show. But when the newly minted star attends a Women's Club luncheon, a socialite sitting at her table suddenly falls face-first into the chicken salad, never to nibble again.

Duy, Phong, Minh, and Edmond have been best friends since childhood. Now, as young men running their families’ formidable businesses, they make up Saigon’s most powerful group of friends in 1928 Vietnam’s elite society. Until one of them is murdered. In a lavish mansion on a hill in Dalat, all four men have gathered for an evening of indulgence, but one of them won’t survive the night.

Quill has lived on the Red Pine reservation in Minnesota her whole life. She knows what happens to women who look like her. Just a girl when Jimmy Sky jumped off the railway bridge and she ran for help, Quill realizes now that she’s never stopped running. As she trains for the Boston Marathon early one morning in the woods, she hears a scream. When she returns to search the area, all she finds are tire tracks and a single beaded earring.

Twenty-three-year-old Michael “Mitt” Fuller starts his surgical residency with great anticipation at the nearly three-hundred-year-old, iconic Bellevue Hospital, following in the footsteps of four previous, celebrated Fuller generations. The pressure is on for this newly minted doctor, and to his advantage he’s always had a secret sixth sense, a sensitivity to the nonphysical. But quickly one patient after another assigned to his care begin to die from mysterious causes.