Thirty-five-year-old Arabella, a New York theatre director whose dating and career prospects are drying up, is offered an opportunity to direct a risqué cross-dressing interpretation of a Shakespeare classic—that might garner international attention—in the West Bank. Her mother, Naya, and grandmother, Zoya, hatch a plot to match her with Aziz, a Palestinian American doctor volunteering in Gaza. Arabella agrees to meet Aziz, since her growing feelings for Yoav, a celebrated Israeli American theatre designer, seem destined for disaster.

Since her husband’s unsolved murder three years ago, Iris Blodgett’s life has unraveled. Awash in grief and buried in debt, she can’t pay her mortgage—and now that she’s lost her job, she has no idea how she’ll provide for her unruly teenage daughter, Ellory. Facing eviction, Iris turns to her new beau, prominent architect Hugh Smoll, for a shoulder to cry on. But the seemingly perfect Hugh offers her something more: an invitation to move in to his mother’s centuries-old mansion while he renovates the property.

Sigrid hates working at the Dollar Pal, but having always resisted the idea of growing up into the trappings of adulthood, she did not graduate high school, preferring to roam the streets of her small town with her best friend Greta, the only person in the world who ever understood her. Her older sister Margit is baffled and frustrated by Sigrid’s inability to conform to the expectations of polite society.

The next step in Ellie Baker’s marriage: divorce. She and her husband, Jonah, are heading to Florida to break it to the family. No great drama to share. After twenty years of marriage, they’ve just fallen out of love. Simple. Not to their college-age daughter, Maggie, who is devastated. Or to Ellie’s father, Frank, who grows as cold as a retiree can get in Orlando. As for Ellie’s mother, Bunny: no, no, no. She doesn’t want to hear it. After a dreadful weekend, Ellie and Jonah return home to New Jersey with hearts and minds still set on a split.

The daughter of a Taiwanese father and white mother, Vi Liu has never quite fit into her Midwestern college town. Aimless after getting dumped by her boyfriend and dropping out of college, Vi works at the front desk of a hotel where she greets guests, refills cucumber water samovars, and tries to evade her bubbly blond coworker, Rachel. Little does Vi know her life is about to be permanently transformed when she agrees to a night out with Rachel. In the alley outside the bar, Vi discovers a strange blob—a small living creature with beady black eyes.