His name was Joshua Silver. He was 23 years old, educated, and had an impressive vocabulary. The NYPD had found Joshua Silver naked in Times Square, barking like a dog. It was just another night for Julie Holland, the attending doctor in the world famous Bellevue Hospital's psychiatric emergency room.

Dr. Jamison is one of the foremost authorities on manic-depressive (bipolar) illness; she has also experienced it firsthand. For even while she was pursuing her career in academic medicine, Jamison found herself succumbing to the same exhilarating highs and catastrophic depressions that afflicted many of her patients, as her disorder launched her into ruinous spending sprees, episodes of violence, and an attempted suicide.

In medical school, Paul Farmer found his life’s calling: to cure infectious diseases and to bring the lifesaving tools of modern medicine to those who need them most. Tracy Kidder’s magnificent account shows how one person can make a difference in solving global health problems through a clear-eyed understanding of the interaction of politics, wealth, social systems, and disease. Profound, Mountains Beyond Mountains takes us from Harvard to Haiti, Peru, Cuba, and Russia as Farmer changes people’s minds through his dedication to the philosophy that “the only real nation is humanity.”

With poignant insight and humor, Frank Vertosick, Jr., MD, describes some of the greatest challenges of his career, including a six-week-old infant with a tumor in her brain, a young man struck down in his prime by paraplegia, and a minister with a .22-caliber bullet lodged in his skull. Told through intimate portraits of Vertosick's patients and unsparing-yet-fascinatingly detailed descriptions of surgical procedures, When the Air Hits Your Brain illuminates both the mysteries of the mind and the realities of the operating room.

By turns heartbreaking, hilarious, and utterly human, The House of God is a mesmerizing and provocative journey that takes us into the lives of Roy Basch and five of his fellow interns at the most renowned teaching hospital in the country.

“Pat, we need to kill the dog.” When a sudden mental illness struck his wife, Patrick Dylan found himself living with an eerie stranger. Scared and unprepared, he began a desperate battle to protect her from a mysterious disease, shelter their children from her bizarre behavior, and recover the woman he loved. Within weeks, she had been admitted to the emergency room, the hospital, and the local crisis facility, but none of the experts could provide an answer. As her illness eluded diagnosis, the family’s struggle was only beginning.

Los Angeles, 1920s: Socialite Mirielle West's days are crowded with shopping, luncheons, and prepping for the myriad glittering parties she attends with her actor husband, Charlie. She's been too busy to even notice the small patch of pale skin on the back of her hand. Other than an occasional overindulgence in gin and champagne, which helps to numb the pain of recent tragedy, Mirielle is the picture of health. But her doctor insists on more tests, and Mirielle reluctantly agrees. The diagnosis - leprosy - is devastating and unthinkable.

An epic story told by a unique voice in Ameri­can medicine, One Doctor describes life-changing experiences in the career of a distinguished physi­cian. In riveting first-person prose, Dr. Brendan Reilly takes us to the front lines of medicine today.

An intimate, moving book written with the immediacy and directness of one who still struggles with the effects of mental and chronic illness, The Collected Schizophrenias cuts right to the core. Schizophrenia is not a single unifying diagnosis, and Esmé Weijun Wang writes not just to her fellow members of the “collected schizophrenias” but to those who wish to understand it as well.

The 2:00 a.m. call is the first time Lexie Vidler has heard her sister's voice in years. Annie is a drug addict, a thief, a liar - and in trouble, again. Lexie has always bailed Annie out, given her money, a place to sleep, sent her to every kind of rehab. But this time, she's not just strung out - she's pregnant and in premature labor. If she goes to the hospital, she'll lose custody of her baby - maybe even go to prison. But the alternative is unthinkable.

With compassion and candor, leading neurosurgeon Henry Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life. If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached surgeons, this gripping, brutally honest account will make you think again.

David Oshinsky, whose last book, Polio: An American Story, was awarded a Pulitzer Prize, chronicles the history of America's oldest hospital and in so doing also charts the rise of New York to the nation's preeminent city, the path of American medicine from butchery and quackery to a professional and scientific endeavor, and the growth of a civic institution.

This compassionate, personal, and illuminating work of nonfiction draws on the author's celebrated work as a director of socially conscious theater to connect listeners with the power of an ancient artistic tradition. For years Bryan Doerries has been producing ancient tragedies for current and returned servicemen and women, addicts, tornado and hurricane victims, and a wide range of other at-risk people in society.

Dr. William Wright gave up a suburban practice as an ear surgeon to become the doctor at Colorado's maximum-security prison. After that, running a medical clinic at the county jail should be a snap, right? Oh, brother. Hoards of desperate people fresh from the streets, homeless addicts, illegal aliens, and gangbangers all ruled by a corrupt sheriff and his concubine sidekick made the supermax look almost pastoral.

In a book as eye-opening as it is riveting, practicing nurse and New York Times columnist Theresa Brown invites us to experience not just a day in the life of a nurse but all the life that happens in just one day in a hospital's cancer ward. In the span of 12 hours, lives can be lost, life-altering medical treatment decisions made, and dreams fulfilled or irrevocably stolen.