In Rooms for Vanishing, the violence of war has fractured the universe for the Altermans, a Jewish family from Vienna. Moving across decades, and across the world, the novel finds the Altermans alone in their separate futures, haunted by the loss of their loved ones, each certain that they are the sole survivor of their family.

Jane and Dan have been married for nineteen years, but Jane isn’t sure they’re going to make it to twenty. The mother of two feels unneeded by her teenagers, and her writing career has screeched to an unsuccessful halt. Her one published novel sold under five hundred copies. Worse? She’s pretty sure Dan is cheating on her. When the couple goes to the renowned upscale restaurant La Fin du Monde to celebrate their anniversary, Jane thinks it’s as good a place as any to tell Dan she wants a divorce.

Claire is excited to drop off a surprise workday lunch for her fiancé, Noah. It’s their anniversary, after all. But when the receptionist tells her that no one with Noah’s name works there, Claire thinks there must be a mistake. Noah isn’t picking up her calls. Her texts go unanswered. It turns out Noah has a different life . . . one with a beautiful girlfriend, a beautiful house. Claire was never really in the picture.

Rabbi Sholem Shachne Katzenellenbogen’s world, the world of his forefathers, is crumbling before his eyes. And in his own home! His eldest, Bentzion, is off in Bialystok, studying to be a businessman; his daughter Bluma Rivtcha is in Vilna, at nursing school. For her older sister, Tilza, he at least managed to find a suitable young rabbi, but he can tell things are off between them. Naftali Hertz? Forget it; he’s been lost to a philosophy degree in Switzerland (and maybe even a goyish wife?). And now the rabbi’s youngest, Refael’ke, wants to run off to the Holy Land with the Zionists.

Predicting a global pandemic in a hit movie was impressive. Writing a sequel that will work for today’s world might take a whole different kind of intelligence. Join Scott Z. Burns, the acclaimed screenwriter of Contagion, as he embarks on a mind-bending quest to create a worthy follow-up to his eerily prophetic film. Reuniting with director Steven Soderbergh, members of the cast and crew, and the scientific experts who advised him on the first film, Burns also turns to an unexpected collaborator: artificial intelligence.