Three very different girls sign up as trainee nurses at a big London teaching hospital in 1934. Dora leaves her overcrowded, squalid working-class home for a better life. But has she got what it takes to keep up with other, better-educated girls? And will her hated stepfather ever let her go? Helen is born for the job; her brother is a doctor, her all-powerful mother a hospital trustee. But will Helen’s secret misery be her downfall? An aristocratic rebel, Millie’s carefree attitude will find her up in front of Matron again and again. Will she ever care enough to make a nurse? Or will she go back to the glamorous life she was born to?

In postwar Tarabeg, two women are waiting for ambitious Michael Malone to return home. Rosie is the local schoolteacher, and most people think she is promised to him. Just a few have guessed that he has secretly begun to woo Sarah, whose brutal fisherman father would kill her if he knew. Both Rosie and Sarah love Michael, both hope to become his wife and their lives will interweave in a tale of tangled secrets, old promises and new feuds. Michael Malone's choice will have fateful consequences for everyone - especially, in due course, for his young daughter....

Bristol 1936. Jenny Crawford has resigned herself to a loveless marriage living hand to mouth with their two children. Like many others, husband Roy struggles to find work at the docks but a chance encounter turns the family's fortunes around. Not only does he get regular work but they are also allocated a council house on Coronation Close on the outskirts of the city. Jenny and the children are overjoyed, this is the fresh start she could only ever dream of. But trouble feels never too far away.

West Yorkshire, 1926. After completing her training in Steeple Street, Agnes is looking forward to making her mark as the village's first district nurse, confident she can make a difference in the locals' lives. But when she arrives, she's treated with suspicion, labelled just another servant of the wealthy mine owners. The locals would much rather place their trust in the resident healer, Nella Black.

Cambridgeshire - March 1939. As the clouds of war begin to gather in Europe, the Talbot family of rural Blackberry Farm will be torn apart, just as so many families all over the world will be. Life will never be the same again. Whilst in London, the Salmons family will feel the pain of parting and loss. Brought together by war, the two families become intertwined and, as the outlook looks bleak, they must draw on each other’s strength to fight through the hard times.

1940, Liverpool: Alice Turner and her best friend, Millie Markham, work for the war effort at Rootes munitions factory, making shell caps and Halifax bombers. Alice’s sweetheart, Terry, is home from the front for a brief period of leave. But the honeymoon is soon over. Terry must go back to the dangers of Nazi-occupied France, and the ever-present air raid sirens quickly bring Alice back down to earth.

When sixteen-year-old Sally is evacuated to the English south coast, she is terrified by what lies ahead of her. All she knows are the sights and sounds of London's East End – but Sally swallows her tears as they leave the familiar landmarks behind, knowing that she has to be a Grown-Up Girl and play mother to her six-year-old brother Ernie. Playing mother is nothing new for Sally – their real mother Florrie, a good-time girl, hasn't even come to the station to wave them off and Ernie, crippled at an early age by polio, is used to depending on his older sister.

At the age of 22, Jennifer Worth left her comfortable home to move into a convent and become a midwife in postwar London’s East End slums. The colorful characters she met while delivering babies all over London - from the plucky, warm-hearted nuns with whom she lived to the woman with 24 children who couldn't speak English to the prostitutes and dockers of the city’s seedier side - illuminate a fascinating time in history.

The three sisters of Victory Walk in East London will face heartache and tears on the home front. As rationing, blackouts and bombs start to bite, life will change forever for the three sisters.

Cassandra Hale grew up knowing little about her parentage, and she had made peace with the fact that she never would. But her world shifts when a shocking deathbed confession reveals a two-year-old letter from Mr. Clark, the master of Briarton Park, with hints to her family’s identity. Stung by betrayal, Cassandra travels to the village of Anston only to learn Mr. Clark has since passed away.

Welcome to the district nurses' home on Steeple Street, where everyone has a secret.... Ambitious young nurse Agnes Sheridan had a promising future ahead of her until a tragic mistake cost her the love and respect of everyone around her. Now she has come to Leeds for a fresh start as a trainee district nurse. But Agnes finds herself facing unexpected challenges as she is assigned to Quarry Hill, one of the city's most notorious slums.

Clara Newton is the new Housemother of Shilling Grange Orphanage. Many of the children have been bombed out of their homes and left without families, their lives torn apart by the war, just like Clara’s. Devastated by the loss of her fiancé, a brave American pilot, she is just looking for a place to start again. But the orphans are in desperate need of her help.

When Sally, Beth, Margaret and Rachel meet at a job interview for the wonderful new store in Oxford Street, they have no idea they will become lifelong friends. When all four girls are lucky enough to be selected as sales staff their exciting new adventure begins. Join them as they overcome heartbreak and grief, find love and happiness and remain united in their friendship, whatever life throws at them.

Bristol 1939. At forty years of age, Mary Anne Randall still turns heads. With an abusive husband spending most of his wages on beer, she has resigned herself to be the sole breadwinner to protect her family and keep the wolves from the door. In order to make ends meet, Mary Anne runs a pawnbroking business from the wash house at the end of the garden. Following the outbreak of war an opportunity presents itself to escape her loveless marriage and find true love. Will she take that chance, or carry on living just for her children and not for herself?

The war has ended; the men are returning home to their loved ones, but for some, things have changed. Charlotte Hennessey-White's husband, David, is no longer the gentle loving man he once was and Charlotte, so independent during the war, is devastated. Edna Burbage's strong fiancée, Colin, has suffered appalling physical injuries. He won’t hold her to her promise of marriage, but she insists her feelings are unchanged. But is that true? And Polly Chandler's sweetheart, Gavin, who’d she’d planned her whole future around, hasn’t come home at all.

Three very different girls sign up as trainee nurses at a big London teaching hospital in 1934. Dora leaves her overcrowded, squalid working-class home for a better life. But has she got what it takes to keep up with other, better-educated girls? And will her hated stepfather ever let her go? Helen is born for the job; her brother is a doctor, her all-powerful mother a hospital trustee. But will Helen’s secret misery be her downfall? An aristocratic rebel, Millie’s carefree attitude will find her up in front of Matron again and again. Will she ever care enough to make a nurse? Or will she go back to the glamorous life she was born to?

Alice Lake has arrived in London from Liverpool to start her training as a District Nurse, but her journey has been far from easy. Her parents think that she should settle down and get married, but she has already had her heart broken once and isn’t about to make the same mistake again. Alice and her best friend, Edith, are based in the East End, but before they’ve even got their smart new uniforms on, war breaks out, and Hitler’s bombs are raining down on London.

As Britain stands alone against a monstrous enemy, the inhabitants of Pearl Street face hardship and heartbreak with courage and humour. The war touches each of them in a different way: for Annie Poulson, a widow, it means never-ending worry when her twin boys are called up and sent to France; Sheila Reilly's husband, Cal, faces the terror of U-Boat attacks; Eileen Costello is liberated from a bitter, loveless marriage when her husband is sent to Egypt.

When sixteen-year-old Sally is evacuated to the English south coast, she is terrified by what lies ahead of her. All she knows are the sights and sounds of London's East End – but Sally swallows her tears as they leave the familiar landmarks behind, knowing that she has to be a Grown-Up Girl and play mother to her six-year-old brother Ernie. Playing mother is nothing new for Sally – their real mother Florrie, a good-time girl, hasn't even come to the station to wave them off and Ernie, crippled at an early age by polio, is used to depending on his older sister.

Liverpool, 1940. When her childhood sweetheart, Johnny, is killed in action, Maxine Grey loses more than her husband - she loses her best friend. Desperate to make a difference in this awful war, Maxine takes a nursing job at London’s St Thomas’ hospital. She takes comfort in the attentions of a handsome surgeon, but Edwin Blake isn’t all he seems. And as the Blitz descends on the capital, Maxine faces more heartache. When she returns to Liverpool, she harbours a secret.

In 1964, Maggie wakes to find herself in a mental asylum, with no idea who she is or how she got there. Remnants of memories swirl in her mind - a familiar song, a storm, a moment of violence. Slowly, she begins to piece together the past and the events which brought her to this point.

At the age of 22, Jennifer Worth left her comfortable home to move into a convent and become a midwife in postwar London’s East End slums. The colorful characters she met while delivering babies all over London - from the plucky, warm-hearted nuns with whom she lived to the woman with 24 children who couldn't speak English to the prostitutes and dockers of the city’s seedier side - illuminate a fascinating time in history.

East London, 1888 - a city apart. A place of shadow and light where thieves, whores, and dreamers mingle, where children play in the cobbled streets by day and a killer stalks at night, where bright hopes meet the darkest truths. Here, by the whispering waters of the Thames, Fiona Finnegan, a worker in a tea factory, hopes to own a shop one day, together with her lifelong love, Joe Bristow, a costermonger's son. With nothing but their faith in each other to spur them on, Fiona and Joe struggle, save, and sacrifice to achieve their dreams.

It’s the summer of 1919, and Ellen O’Brien has her whole life ahead of her. Young, in love and leaving home for her first job, the future seems full of shining possibility. But war is brewing, and before long, Ellen and everyone around her are swept up by it. As Ireland is torn apart by the turmoil, Ellen finds herself facing the ultimate test of love and loyalty. A hundred years later and Clare Farrell has inherited a dilapidated old farmhouse in County Meath.

Mary Doyle arrives in Dublin in 1913, doomed, she fears, to a life of domestic service. Instead, however, she finds herself deeply affected by the social and political turmoil of a fledgling nation struggling for independence. Suddenly, all that was once inevitable is no longer a certainty as she is embroiled in the very heart of the Easter Rising.

For three young boys, Liam, Patrick, and Hugo, life in Ireland of the 1960s proves to be both idyllic and flawed. Living in close proximity but leading vastly different lives, the bonds of friendship bind these young men as they grow, dream, and navigate the storms of youth.

The truth hurts.... Erin and Roisin were friends until a fatal accident ruined both their lives. Now Roisin has discovered a secret - one Erin has kept for over a decade - and she's determined to make Erin pay for her lies. Erin wants nothing to do with Roisin. She has a new life in London and no intention of going back home. Yet when her father is mysteriously and critically injured, Erin has no choice but to return and face Roisin - and her past.

When Lucy Bagshaw's life in Boston falls apart thanks to a scathing editorial written by her famous artist mother, she accepts her half-sister Juliet's invitation to stay with her in Hartley-by-the-Sea, a charming seaside village in Northern England. Lucy is expecting quaint cottages and cream teas but instead finds that her sister is an aloof host; the weather is wet, windy, and cold; and her new boss, Alex Kincaid, is a disapproving widower who hired her only as a favor to Juliet.

On a leafy suburban street in Dublin, beautiful, poised Stella Greene lives with her successful husband, Matt. They're the perfect couple in every way, and Stella appears to have it all. Next door, at number 72, however, lives Rea Brady. Gruff, bad tempered and rarely seen besides the twitching of her net curtains, rumour has it she's lost it all...including her marbles, if you believe the neighbourhood gossip. But appearances can be deceiving, and when Stella and Rea's worlds collide they realise they have much in common.

When a mysterious note arrives for six months pregnant Dr Eliana Hughes, she begins to doubt every aspect of her life - from her mixed feelings about motherhood to her marriage to Martin, who has become distant in recent months. As the person behind the note escalates their campaign to out Eli’s husband as a cheat, she finds herself unable to trust even her own instincts, and as pressure builds, she makes a mistake that jeopardises her entire future. Elsewhere, someone is watching.