Psychology professor Jackie Strelitz thinks she’s over Harlan Crispin, her ex-lover and colleague. Why should she care if Harlan springs a new “friend” on her? After all, Jackie has everything she ever wanted: a loving husband and a thriving career. Still, she can’t help but be curious about Harlan’s latest. Nasira Amari is graceful, smart, and appallingly young. Worse, she’s the newest member of Jackie’s research team.

Chesapeake Bay, 1980. Eighteen-year-old Verity Vergennes is the captain of the USS Nepenthe, and her seven younger siblings are her crew. The ship - an oyster boat transformed into a make-believe destroyer - is the heart of the Vergennes family, a place both to play and to learn responsibility. But Verity’s had it with being tied to the ship and secretly applies to a distant college. If only her parents could bear to let her go. Maeve and Arthur Vergennes already suffered one loss when, five years earlier, their eldest son, Jude, stormed out and never returned.

Single mother Maisey Addington has always fallen short of her own mother’s expectations - never married, a bit adrift, wasting her high IQ on dead-end jobs. The only thing Maisey’s sure she’s gotten right is her relationship with her twelve-year-old daughter, Elle...until a phone call blows apart the precarious balance of their lives. Maisey’s mother is in a coma, and her aging father faces charges of abuse and neglect.

An inheritance has reunited three estranged cousins. Their grandmother Lucy left Nessa, Flynn, and April her cabin nestled in the woods near Blossom, Texas, as well as a hope chest to be unlocked after they complete a special task. Together, they must hand stitch a cherished quilt Lucy left unfinished. It meant everything to her. And now, to three people struggling with their own patchwork pasts.

Vermont, 1972. Carole LaPorte has a satisfying, ordinary life. She cares for her children, balances the books for the family's auto shop, and laughs when her husband slow dances her across the kitchen floor. Her tragic childhood might have happened to someone else. But now her mind is playing tricks on her. The accounts won't reconcile and the murmuring she hears isn't the television.

Annie Beyers has everything - a beautiful house, a loving husband, and an adorable daughter. It’s a day like any other when she takes Hannah to the pediatrician…until she wakes hours later from a car accident. When she asks for her daughter, confused doctors tell Annie that Hannah never existed. In fact, nothing after waking from the crash is the same as Annie remembers. Five happy years of her life apparently never happened.

Olivia McAfee knows what it feels like to start over. Her picture-perfect life—living in Boston, married to a brilliant cardiothoracic surgeon, raising their beautiful son, Asher—was upended when her husband revealed a darker side. She never imagined that she would end up back in her sleepy New Hampshire hometown, living in the house she grew up in and taking over her father’s beekeeping business. Lily Campanello is familiar with do-overs, too. When she and her mom relocate to Adams, New Hampshire, for her final year of high school, they both hope it will be a fresh start.

Maine, 1969. After losing her parents in a car accident, aspiring artist Annalisa Mancuso lives with her grandmother and their large Italian family in the stifling factory town of Payton Mills. Inspired by her mother, whose own artistic dreams disappeared in a damaged marriage, Annalisa is dedicated only to painting. Closed off to love, and driven as much by her innate talent as she is the disillusionment of her past, Annalisa just wants to come into her own.

Steph has spent decades building a family with her husband, Mal, and putting their family first. She is the glue that holds them all together, and she has convinced herself that she’s been happy...most of the time. But as she stands at her birthday party watching her husband talking about a wonderful marriage she doesn’t fully recognise, the doubts that she has been pushing down for so long begin to grow.

Emotionally guarded Daphne Amos always believed she’d found a kindred spirit in her fiancé, Heath. Both very private people, they’ve kept their pasts hidden from the world, and each other, until Heath’s escalating nightmares begin to put an undeniable strain on their relationship. Determined to give their impending marriage the best chance of succeeding, Heath insists that Daphne join him on a seven-day retreat with Dr. Matthew Cerny, a psychologist celebrated for getting to the root of repressed memories.

Lillie Silva knew life as an empty nester would be hard after her only child left for college, but when her husband abruptly dumps her for another woman just as her son leaves, her world comes crashing down. Besides the fact that this announcement is a complete surprise (to say the least), what shocks Lillie most is that she isn't...heartbroken. She's furious. Lillie has loved her life on Cape Cod, but as a mother, wife and nurse-midwife, she's used to caring for other people...not taking care of herself.

December 1943. In the years before the rise of Hitler, the Gerber family’s summer cottage was filled with laughter. Now, as deep drifts of snow blanket the Black Forest, German dissenter Franka Gerber is alone and hopeless. Fervor and brutality have swept through her homeland, taking away both her father and her brother and leaving her with no reason to live.

As a hospice nurse, Zara Mitchell has already seen more death than most people will experience in a lifetime. So when her older sister asks her to help care for their ailing grandmother, Zara agrees - despite strained family relationships. Though pale and tired, Nonna has lost none of her sharp mind. She’s fixated on finding something long forgotten, and she immediately puts Zara to work cleaning out the attic. Amid the tedium of sifting through knickknacks and heirlooms, Zara also reconnects with a man she’s attracted to but whose complicated past makes romance seem impossible.

When a shipwreck surfaces, old secrets are sure to follow. Or so goes the lore in Ivy Neale’s hometown of Nags Head, North Carolina. When Ivy inherits her family’s beachfront cottage upon her grandmother’s death, she knows returning to Nags Head means facing the best friend and the boyfriend who betrayed her years ago. But then a winter gale uncovers the shipwreck of local legend—and Ivy soon begins to stumble across more skeletons in the closet than just her own.

William Waters grew up in a house silenced by tragedy, where his parents could hardly bear to look at him, much less love him—so when he meets the spirited and ambitious Julia Padavano in his freshman year of college, it’s as if the world has lit up around him. With Julia comes her family, as she and her three sisters are inseparable: Sylvie, the family’s dreamer, is happiest with her nose in a book; Cecelia is a free-spirited artist; and Emeline patiently takes care of them all.