A television talk show host returns to her childhood summer home to rebuild her life after she's fired for falling ratings. The return is bittersweet as the house has been neglected for years. She's flooded with memories of the wonderful summers she spent with her sisters and cousins before a tragic event changed everything. Working to uncover what really happened the last summer they were all together, she reaches out to her family and the women all gather for an uneasy family reunion.

Between the urban bustle of Denver and the high-stress environment of a career in neurosurgery, Maggie Sullivan has hit a wall. When an emergency high-risk procedure results in the death of a teenager, Maggie finds herself in the middle of a lawsuit - and experiencing levels of anxiety she's never faced before. She knows she needs to slow down before she burns out completely, and the best place she can think to do that is Sullivan's Crossing.

Nikki Burgess survived a terrible marriage and a worse divorce. She's just about given up hope of ever finding happiness. But when her ex-husband suddenly dies, she gets custody of her kids again - and a chance to start over. Dixie McPherson, on the other hand, has had way too much love. She has 11 tennis bracelets, dozens of trinkets, piles of sexy lingerie, and a tarnished reputation when all she ever wanted was true love, a partner, and a family. Carlisle Bartlett is loyal, kindhearted, and the funniest guy slinging drinks in the back of an airplane. But he has an ugly little secret. The only kind of love he's used to comes with bruises.

From the outside looking in, Lauren Delaney has a life to envy - a successful career, a solid marriage to a prominent surgeon, and two beautiful daughters who are off to good colleges. But on her 24th wedding anniversary, Lauren makes a decision that will change everything. Lauren won’t pretend things are perfect anymore. She defies the controlling husband who has privately mistreated her throughout their marriage and files for divorce. And as she starts her new life, she meets a kindred spirit - a man who is also struggling with the decision to end his unhappy marriage.

Widowed at thirty-three with two small kids, Beverly Simpson wants someone to blame. Angry, hurt, and full of regret for what she’s lost, she rails against a once trusted God and hides her loneliness behind a sassy exterior. Joe Clark, intrigued by Bev’s irreverent approach to life, stubbornly pursues her. However, the pair have two very different outlooks on life. Joe is a dedicated preacher, while Bev insists she no longer even believes in God.