It’s 2011 and Deecie Jeffries’s missing person’s case in Austin, Texas, is still cold. New mom Bee, struggling with postpartum depression, is living in Portland, Maine, having left Austin–and those memories–far behind. Until Leo, her childhood crush and her estranged twin Gus’s best friend, suddenly resurfaces, drawing Bee back into their shared past. Bee’s predictable life is upended, pushing her to return to her childhood home and piece together a neighborhood’s shattered history.

On a highway in Houston, Texas, Sarah LaBrie’s mother was found screaming at passing cars, terrified she would be murdered by invisible assailants. The diagnosis of schizophrenia that followed compelled Sarah to rethink her childhood, marked at turns by violence and all-consuming closeness. Digging into the events that led to her mother’s break, Sarah traces her family history of mental illness, from the dysphoria that plagued her great-grandmother, a granddaughter of slaves, to her own experience with depression as a scholarship student at Brown.

In A Kid from Marlboro Road, past and present intermingle as family stories are told and retold. The narrative careens between the prior generation’s colorful sojourns in the Bronx and Hell’s Kitchen and the softer world of Gibson, the town on Long Island where they live now. There are scenes in the Rockaways, at Belmont racetrack, and in Montauk. Edward Burns’s buoyant first novel is a bildungsroman, yet out of one boy’s story a collective warmth emerges, a certain kind of American tale, raucous and joyous.

It is said that when one person in a family is unstable, the whole family is destabilized. Meet the Shreds. Olivia is the sister in the spotlight until her stunning confidence becomes erratic and unpredictable, a hurricane leaving people wrecked in her wake. Younger sister Amy, cautious and studious to the core, believes in facts, proof, and the empirical world. None of that explains what’s happening to Ollie, whose physical beauty and charisma mask the mental illness that will shatter Amy’s carefully constructed life.

Bea Abramovitz has a gift for math and numbers. With her father, she studies the burgeoning Wall Street market’s stocks and patterns in the financial pages. After college she’s determined to parlay her talent for the prediction game into personal and professional success. But in the 1920s, in a Lower East Side tenement, opportunities for women don’t just come knocking. Bea will have to create them.