One dark evening on New York City’s Upper West Side, two strangers meet by chance. Over drinks, Amanda and Wendy realize they have much in common, including an intense desire for revenge against the men who destroyed their families. As they talk into the night, they come up with the perfect plan: if you kill for me, I’ll kill for you.

One year ago, Lucy’s sister, Nicki, left to meet friends at a pub in Dublin and never came home. The third Irish woman to vanish inexplicably in as many years, the agony of not knowing what happened that night has turned Lucy’s life into a waking nightmare. So, she’s going to take matters into her own hands. Angela works as a paper-pusher in the Missing Persons Unit, but wants nothing more than to be a fully fledged member of An Garda Síochána, the Irish police force. With the investigation into the missing women stalled, she begins pulling on a thread that could break the case wide open.

When Anna Hartley’s husband, Henry, calls her with a terrible, guilty confession, she can’t believe what she hears. It has to be a bad joke—the mild, predictable artist she married would never hurt a fly, let alone commit murder. But her confusion turns to horror when police find his body washed up on the banks of the Rio Grande.

Lyla is in a bit of a rut. Her post-doctoral research has fizzled out, she’s pretty sure they won’t extend her contract, and things with her boyfriend, Nico, an aspiring actor, aren’t going great. When the opportunity arises for Nico to join the cast of a new reality TV show, One Perfect Couple, she agrees to try out with him. A whirlwind audition process later, Lyla finds herself whisked off to a tropical paradise with Nico, where the two of them will compete against four other couples in order to win a cash prize. But not long after they arrive, things start to go wrong.

For the past five years, Ryan Richardson has relived that terrible night. The car door ripping open. The crushing blow to the head. The hands yanking him from the vehicle. His girlfriend Ali’s piercing scream as she is taken. With no trace of Ali or the car, a cloud of suspicion hangs over Ryan. But with no proof and a good lawyer, he’s never charged, though that doesn’t matter to the podcasters and internet trolls. Now, Ryan has changed his last name, and entered law school. He's put his past behind him. Until, on a summer trip abroad to Italy, Ryan gets a call from his father.

After the killing of a prominent mob lawyer, NYPD homicide detectives Jacob Jackson and Caitlin Grimes start receive chilling, written “rules” for how to commit the perfect murder. "Rule number one for the perfect murder: Evidence is your enemy. Leave none behind." Jackson (Reid Scott) and Grimes (Cobie Smulders) race to find the killer, setting them on a collision course with the city’s crime underbelly, and a perpetrator who seems happy to toy with them. “Rule number two. No crimes of passion. The perfect murder is always business, never pleasure.”

Kidnappers grabbed Jenna in broad daylight, right in front of her children and their horrified classmates. Her family was issued an insane ransom demand: $25 million in cash and jewels, payable by the end of the school day, otherwise they’ll never see her again. As Jenna’s mother scrambles to gather the money, detectives Mo Butler and George Ortega follow the trail of the kidnappers, which will lead them through a sordid landscape of jealous lovers, broken dreamers, and twisted schemers. But every second counts, and there’s one thing Jenna Wade doesn’t have: very much time.

When Heather McKinley dreamed of becoming a doctor, she imagined curing sick kids and sporting pink stethoscopes. She never anticipated the sleepless nights, grueling exams, and endless labs. And she certainly never knew that her medical school earned the nickname Dead Med thanks to the tragic history of students overdosing on illegal drugs. But Heather would never consider doing anything like that. That is, until her longtime boyfriend dumps her, she finds herself failing anatomy, and her world starts to crumble.

Lowen Ashleigh is a struggling writer on the brink of financial ruin when she accepts the job offer of a lifetime. Jeremy Crawford, husband of best-selling author Verity Crawford, has hired Lowen to complete the remaining books in a successful series his injured wife is unable to finish. Lowen arrives at the Crawford home, ready to sort through years of Verity's notes and outlines, hoping to find enough material to get her started. What Lowen doesn't expect to uncover in the chaotic office is an unfinished autobiography Verity never intended for anyone to read.

Cassie thinks she has met the perfect man. Joel is sweet, handsome, romantic, and best of all, he’s crazy about Cassie. She thinks she’s found the guy she’ll spend the rest of her life with. Have children with. Grow old with. Yes, she knows about his perfect ex-girlfriend, Francesca. The beautiful, brilliant chef, beloved by all his friends. But she thinks Francesca is out of the picture. She thinks Francesca is gone for good. Think again, Cassie.

Jenny sits in the same seat on the same train every week, seeing familiar faces come and go. Until a chance encounter shatters her world. Sixteen years ago, Jenny survived a traumatic ordeal that left her best friend, Susie, missing and presumed dead. The world has its theories about what happened to Susie Patterson, and one of those theories points the finger at Jenny. Now she lives a quiet life, volunteering at a crisis helpline while trying to deal with her own anxiety and the true crime fans obsessed with finding her missing friend.

Jazz Bashara is a criminal. Well, sort of. Life on Artemis, the first and only city on the moon, is tough if you're not a rich tourist or an eccentric billionaire. So smuggling in the occasional harmless bit of contraband barely counts, right? Not when you've got debts to pay and your job as a porter barely covers the rent. Everything changes when Jazz sees the chance to commit the perfect crime, with a reward too lucrative to turn down.

They were madly in love. The perfect couple. That was the story everyone in South River believed...until Gin Talcott and Adam Archer are found shot in their bed. Adam is dead at the scene. Gin is fighting for her life. Detectives Greta Jessup and Finn Pate are assigned to the case. Greta has a long history with Gin’s first husband, Eddie, and is determined to protect his 18-year-old twins. Piper discovered the bodies. Daniel is missing—and so is Adam’s gun.

Sloan will go through hell and back for those she loves. And she does so, every single day. Caught up with the alluring Asa Jackson, a notorious drug trafficker, Sloan has finally found a lifeline to cling to, even if it’s meant compromising her morals. She was in dire straits trying to pay for her brother’s care until she met Asa. But as Sloan became emotionally and economically reliant on him, he in turn developed a disturbing obsession with her—one that becomes increasingly dangerous every day.

Tess Strebel can’t recognize her own face. She can’t recognize her home. Her bedroom is unfamiliar. And she can’t remember the handsome stranger lying next to her in bed. A stranger who claims he’s her husband. Tess reads a letter in her own handwriting, composed during a rare lucid day, explaining her life as it now exists: she was in a terrible car accident one year ago. Every morning, she wakes up unable to remember most of the last decade. Including her own wedding.