Rita Kennedy has finally seen through her good-for-nothing husband, Charlie. Now he's gone AWOL with his fancy woman and left Rita at the mercy of the local gossips. Her future is full of uncertainty, and the only thing that keeps her going is knowing that her children are safe from the Luftwaffe - and the letters that she receives from Jack Callaghan, her childhood sweetheart, but a life together is just a distant fantasy.

The three sisters of Victory Walk in East London will face heartache and tears on the home front. As rationing, blackouts and bombs start to bite, life will change forever for the three sisters.

Alice Lake has arrived in London from Liverpool to start her training as a District Nurse, but her journey has been far from easy. Her parents think that she should settle down and get married, but she has already had her heart broken once and isn’t about to make the same mistake again. Alice and her best friend, Edith, are based in the East End, but before they’ve even got their smart new uniforms on, war breaks out, and Hitler’s bombs are raining down on London.

Liverpool, 1939. Bella Rogers thought her life was just starting; she can’t wait to get married to her childhood sweetheart, Bobby. But when war is declared and Bobby is called up, his letters stop, leaving Bella heartbroken and alone. Then her family is torn apart by tragedy when her angelic 5-year-old sister dies from a terrible illness. They can barely afford a funeral, but the church is packed with the entire community, devastated for their loss. Grieving for her sister and lost love, Bella finds a job at the Bryant and May factory, making matches.

Cambridgeshire - March 1939. As the clouds of war begin to gather in Europe, the Talbot family of rural Blackberry Farm will be torn apart, just as so many families all over the world will be. Life will never be the same again. Whilst in London, the Salmons family will feel the pain of parting and loss. Brought together by war, the two families become intertwined and, as the outlook looks bleak, they must draw on each other’s strength to fight through the hard times.

When sixteen-year-old Sally is evacuated to the English south coast, she is terrified by what lies ahead of her. All she knows are the sights and sounds of London's East End – but Sally swallows her tears as they leave the familiar landmarks behind, knowing that she has to be a Grown-Up Girl and play mother to her six-year-old brother Ernie. Playing mother is nothing new for Sally – their real mother Florrie, a good-time girl, hasn't even come to the station to wave them off and Ernie, crippled at an early age by polio, is used to depending on his older sister.

Bristol 1936. Jenny Crawford has resigned herself to a loveless marriage living hand to mouth with their two children. Like many others, husband Roy struggles to find work at the docks but a chance encounter turns the family's fortunes around. Not only does he get regular work but they are also allocated a council house on Coronation Close on the outskirts of the city. Jenny and the children are overjoyed, this is the fresh start she could only ever dream of. But trouble feels never too far away.

Welcome to the district nurses' home on Steeple Street, where everyone has a secret.... Ambitious young nurse Agnes Sheridan had a promising future ahead of her until a tragic mistake cost her the love and respect of everyone around her. Now she has come to Leeds for a fresh start as a trainee district nurse. But Agnes finds herself facing unexpected challenges as she is assigned to Quarry Hill, one of the city's most notorious slums.

Bristol 1939. At forty years of age, Mary Anne Randall still turns heads. With an abusive husband spending most of his wages on beer, she has resigned herself to be the sole breadwinner to protect her family and keep the wolves from the door. In order to make ends meet, Mary Anne runs a pawnbroking business from the wash house at the end of the garden. Following the outbreak of war an opportunity presents itself to escape her loveless marriage and find true love. Will she take that chance, or carry on living just for her children and not for herself?

August 1940: As the Luftwaffe swarm over Liverpool, Shane Quinn decides to move his family back to the safety of Ireland. But his only child, the beautiful Dana, would rather stay and serve her country than flee to a foreign land. Determined to make it on her own, she joins the WAAF with newfound pals Patty and Lucy. There’s plenty of excitement to be had on a RAF station, even a chance or two at love.

When Sally, Beth, Margaret and Rachel meet at a job interview for the wonderful new store in Oxford Street, they have no idea they will become lifelong friends. When all four girls are lucky enough to be selected as sales staff their exciting new adventure begins. Join them as they overcome heartbreak and grief, find love and happiness and remain united in their friendship, whatever life throws at them.

West Yorkshire, 1926. After completing her training in Steeple Street, Agnes is looking forward to making her mark as the village's first district nurse, confident she can make a difference in the locals' lives. But when she arrives, she's treated with suspicion, labelled just another servant of the wealthy mine owners. The locals would much rather place their trust in the resident healer, Nella Black.

London, 1940. Bombs fall and Josie Banks’ world crumbles around her. Her overbearing husband, Stan, is unreachable, called to service. Her home, a ruin of rubble and ash. Josie’s beloved tearoom boss has been killed, and Josie herself is injured, with nothing left and nowhere to go. Evacuated to the English countryside, Josie ends up at the estate of the aristocratic Miss Harcourt, a reluctant host to the survivors of the Blitz. Now a threat looms larger than anyone imagined. And a dangerous secret is about to upend Josie’s life again.

As Britain stands alone against a monstrous enemy, the inhabitants of Pearl Street face hardship and heartbreak with courage and humour. The war touches each of them in a different way: for Annie Poulson, a widow, it means never-ending worry when her twin boys are called up and sent to France; Sheila Reilly's husband, Cal, faces the terror of U-Boat attacks; Eileen Costello is liberated from a bitter, loveless marriage when her husband is sent to Egypt.

Susie did something that she knows she will always regret: giving her baby son up for adoption, to keep her infidelity secret from her family. Louise, Susie's daughter, feels the effects of that decision echoing down through the years - her mother has always been difficult, too strict with her but not strict enough with her sister, Grace, who is wild and out of control. And Danny, Susie's husband, adores her but has always sensed something wrong at the heart of their marriage.