632nm

By: Misha Shalaginov Michael Dubrovsky Xinghui Yin
  • Summary

  • Technical interviews with the greatest scientists in the world.
    © 2024 Misha Shalaginov, Michael Dubrovsky, Xinghui Yin
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Episodes
  • The Science of Drug Discovery: Insights from Artem Evdokimov
    Nov 18 2024

    In this episode, drug discovery scientist Artem Evdokimov discusses the science of pharmaceutical development, from historical breakthroughs to the current landscape. He shares insights on antibiotics resistance, the obesity drug Ozempic, and technical details of drug screening methods like DNA-encoded libraries.

    The conversation covers the economics of drug development, the potential of AI, and broader philosophical questions about human health and medicine. Evdokimov emphasizes the importance of avoiding oversimplification in science while highlighting both the triumphs and ongoing challenges in pharmaceutical research.

    03:18 Historical Roots of Medicine
    05:33 Evolution of Drug Delivery Methods
    12:52 Modern Drug Discovery and Challenges
    45:39 Understanding the Drug Discovery Process
    47:30 Challenges in Gene Therapy
    49:26 Complexities of Human Physiology
    53:14 The Role of Receptors and Hormones
    01:28:12 The Selenium Shortage and Shampoo Dilemma
    01:28:54 Challenges in Drug Manufacturing and Distribution
    01:34:23 Antibiotic Resistance: A Growing Concern
    01:45:18 The Future of Drug Discovery and AI
    02:11:01 Exploring AI and Drug Discovery
    02:11:41 Outsourcing in Pharma: Pros and Cons
    02:13:56 High Throughput Screening and Machine Learning
    02:16:37 Challenges and Future of Drug Discovery


    FOLLOW US ON SOCIAL:
    Twitter @ https://x.com/632nmPodcast
    Substack: https://632nmpodcast.substack.com/
    Michael Dubrovsky @ https://x.com/MikeDubrovsky
    Misha Shalaginov @ https://x.com/MYShalaginov
    Xinghui Yin @ https://x.com/XinghuiYin

    SUBSCRIBE:
    Apple Podcasts: https://podcasts.apple.com/us/podcast/632nm/id1751170269
    Spotify: https://open.spotify.com/show/4aVH9vT5qp5UUUvQ6Uf6OR

    WEBSITE:
    https://www.632nm.com

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    2 hrs and 50 mins
  • Optical Metatronics: Nader Engheta on Electromagnetics and Scientific Curiosity
    Nov 11 2024

    In this episode of the 632nm podcast, Nader Engheta shares his journey and experiences within the field of electromagnetics, from his early days at the University of Tehran and Caltech, to his current research in optical metatronics and nonlinear dynamics.

    He discusses the importance of motivation and curiosity in scientific research, the potential of optics in AI, and the exciting new possibilities for combining knowledge from different fields. Engheta also touches on his experiences in industry, interdisciplinary teaching, and offers advice to young researchers.

    02:19 Fascination with Electromagnetics
    03:14 Journey from Tehran to Caltech
    05:39 Exploring Chirality and Metamaterials
    08:21 Innovations in Polarization Imaging
    36:12 Exploring Antennas and Metatronics
    36:46 Dream Job in the Tech Industry
    37:24 Optics and Artificial Intelligence
    39:44 Brain Waves and Neuroscience
    53:20 Optical Computing vs. Electronics
    01:15:55 Exploring Optical and Electronic Constraints
    01:17:47 Optical Computing: Efficiency and Challenges
    01:20:58 Historical Insights and Modern Applications
    01:26:20 Nonlinearity in Optical Systems
    01:32:59 Future Directions and Advice for Young Researchers

    FOLLOW US ON SOCIAL:
    Twitter @ https://x.com/632nmPodcast
    Substack: https://632nmpodcast.substack.com/
    Michael Dubrovsky @ https://x.com/MikeDubrovsky
    Misha Shalaginov @ https://x.com/MYShalaginov
    Xinghui Yin @ https://x.com/XinghuiYin

    SUBSCRIBE:
    Apple Podcasts: https://podcasts.apple.com/us/podcast/632nm/id1751170269
    Spotify: https://open.spotify.com/show/4aVH9vT5qp5UUUvQ6Uf6OR

    WEBSITE:
    https://www.632nm.com

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    1 hr and 55 mins
  • Quantum Computing: Peter Zoller and Ignacio Cirac on the Quantum Revolution
    Nov 4 2024

    In this episode of the 632-nanometer podcast, we explore the evolution of quantum computing with theoretical physicists and experimentalists Peter Zoller and Ignacio Cirac, two pioneers in the field. They recount their personal journeys and discuss key breakthroughs in the development of trapped ion quantum computing.

    What are the fundamental challenges of quantum computing, and how did researchers overcome them? What detection methods were initially considered, and how has the approach evolved? In this podcast, you'll find the answers to these questions and learn about significant milestones, including the early experiments by Dave Wineland and Chris Monroe, as well as the role of fault-tolerant quantum computing and error correction in shaping the future of this technology.

    We also discuss the commercialization of quantum computing, its potential applications, and the future opportunities it presents for young scientists. Zoller and Cirac address foundational questions about quantum physics, the broader implications of their work for science and technology, and share strategic advice for aspiring researchers entering the field.

    01:33 The Meeting of Minds: How We Met
    02:19 Early Collaborations and Research
    03:35 The Birth of Trapped Ion Quantum Computing
    05:51 Challenges and Innovations in Quantum Computing
    08:47 The Role of Atomic Clocks and Other Systems
    15:20 Overcoming Skepticism and Technical Hurdles
    21:28 Advancements and Future Directions
    36:38 Exploring Magnetic Field Gradients in Quantum Computing
    37:00 NMR vs. Ion Trap Quantum Computing
    37:40 Reflecting on Influential Papers and Collaborations
    38:48 Quantum Simulators and Optical Lattices
    40:50 Quantum Communication and Entanglement
    47:42 Solid State vs. AMO Systems
    53:49 The Future of Quantum Computing
    01:02:54 Philosophical and Speculative Questions in Quantum Physics

    FOLLOW US ON SOCIAL:
    Twitter @ https://x.com/632nmPodcast
    Substack: https://632nmpodcast.substack.com/
    Michael Dubrovsky @ https://x.com/MikeDubrovsky
    Misha Shalaginov @ https://x.com/MYShalaginov
    Xinghui Yin @ https://x.com/XinghuiYin

    SUBSCRIBE:
    Apple Podcasts: https://podcasts.apple.com/us/podcast/632nm/id1751170269
    Spotify: https://open.spotify.com/show/4aVH9vT5qp5UUUvQ6Uf6OR

    WEBSITE:
    https://www.632nm.com

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    1 hr and 17 mins

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