• #68 Phylogenetic inference from raw reads and Read2Tree with David Dylus

  • Aug 28 2023
  • Length: 49 mins
  • Podcast

#68 Phylogenetic inference from raw reads and Read2Tree with David Dylus

  • Summary

  • In this episode, David Dylus talks about Read2Tree, a tool that builds alignment matrices and phylogenetic trees from raw sequencing reads. By leveraging the database of orthologous genes called OMA, Read2Tree bypasses traditional, time-consuming steps such as genome assembly, annotation and all-versus-all sequence comparisons.

    Links:

    • Inference of phylogenetic trees directly from raw sequencing reads using Read2Tree (David Dylus, Adrian Altenhoff, Sina Majidian, Fritz J. Sedlazeck, Christophe Dessimoz)
    • Background story
    • Read2Tree on GitHub
    • OMA browser
    • The Guardian’s podcast about Victoria Amelina and Volodymyr Vakulenko

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