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All Access DNA

All Access DNA

By: allaccessdna
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What is DNA anyway? Should I consider genetic testing? Can my genes tell my future? All Access DNA honestly answers the questions you have about genetics, healthcare, and popular issues in precision medicine as it relates to our daily lives. We may even veer into territory that is no longer science fiction but science reality. Host Kate Wilson utilizes her genetic expertise and experience to interview leaders and specialists in genomic medicine and research.Constellation Genetics LLC, Copyright 2025 All rights reserved. Biological Sciences Hygiene & Healthy Living Physical Illness & Disease Science
Episodes
  • Replay: Should I delete my 23andMe data?
    May 27 2025
    This is a replay of our bonus episode that was released on March 28, 2025 and prior to Regeneron Pharmaceuticals purchasing 23andMe. Regeneron entered the asset purchase agreement on May 19, 2025 and states it plans to maintain the consumer genetics business. Regeneron also stated it would prioritize the privacy, security and ethical use of 23andMe's customer data. See more about the announcement here. In this episode, we explore the complexities of genetic data privacy, particularly in light of 23andMe's recent bankruptcy filing. Anya Prince discusses the implications for customer data, the legal protections in place, and the unique risks associated with genetic information. The discussion also covers the challenges of data de-identification, customer rights regarding data deletion, and the potential for data breaches. The conversation concludes with reflections on the global landscape of genetic data privacy and the importance of understanding personal values in relation to data sharing. Key Takeaways: 23andMe's bankruptcy raises concerns about customer data.New ownership of 23andMe or its data could change how genetic data is used.Security breaches pose significant risks to genetic data.Global laws on data privacy vary significantly.Understanding personal values is crucial in data sharing decisions. Anya Prince, Professor of Law, Joseph F. Rosenfield Fellow in Law Professor Prince’s teaching and research interests explore health and genetic privacy, with a particular focus on genetic discrimination, the health privacy implications of big data, and the ethical, legal, and social implications of genomic testing. Her research particularly explores the intersections of social and biological data by interrogating the ethical and legal implications of how genetic data can be used to predict social traits and behaviors and, conversely, how social data can be used to predict medical information, including reproductive information. Her interdisciplinary work has been published in legal, bioethics, and medical journals, including the Boston College Law Review, North Carolina Law Review, Iowa Law Review, JAMA, the American Journal of Bioethics, Journal of Law, Medicine, and Ethics, and Genetics in Medicine. In 2022, she was awarded a four-year R01 grant from the National Human Genome Research Institute (NHGRI) at the National Institutes of Health (NIH) to study the ethical, legal, and social implications of sociogenomic polygenic scores. In 2023, she was awarded a Bridging Bioethics, Research & Policymaking grant from the Greenwall Foundation to develop resources regarding state-level genetic privacy legislation. In addition to these grants, Professor Prince is an investigator, consultant, or advisory board member on multiple other NIH-funded projects. She had previously been awarded a Pathway to Independence Award (K99/R00) from NHGRI to examine the use of genetic information by life, long-term care, and disability insurers. Professor Prince is a former Visiting Assistant Professor of Law at Indiana University’s Robert H. McKinney School of Law, where she taught Employment Law and Genetics and the Law. Before joining the legal academy, she served as a Post-doctoral Research Fellow at the UNC Center for Genomics and Society (CGS) in the Department of Social Medicine at UNC-Chapel Hill School of Medicine. Professor Prince has also worked as a Skadden Fellow and Staff Attorney at the Cancer Legal Resource Center in Los Angeles, California. You can follow her @anyaprince.bsky.social Please subscribe to this podcast on Apple Podcasts, Spotify, YouTube or wherever you get your podcasts to stay updated on new episodes of All Access DNA. Listen to past episodes on your favorite podcast play by searching “All Access DNA” or by streaming from our website at allaccessdna.podbean.com Check out our Patreon at patreon.com/allaccessdna and consider donating to get bonus content, submit questions for our guests, and connect with other genetic-curious individuals. Here are more resources related to today’s topic: Press Release from 23andMe about Voluntary Chapter 11 Initiation23andMe Privacy InformationCalifornia Attorney General Consumer Alert 23andMeHIPAA Information from US Department of Health and Human Services SNP genotyping: technologies and biomedical applicationsArticle from Slate on GEDMatch being Acquired by VerogenArticle from BBC News on 23andMe Profiles Being HackedWhat is GDPR from gdpr.edu Any inquiries on the podcast can be sent to AllAccessDNA@gmail.com Note that this podcast is for entertainment and education and is not intended to be a substitute for professional medical advice. Please consult your physician with any questions you may have regarding your health. The All Access DNA team includes: host, producer and editor Kate Wilson. The logo is designed by Designs by NKJ.
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    38 mins
  • What are sex trait variations and how do we support intersex individuals?
    May 20 2025

    In this conversation, we delve into the complexities surrounding intersex and transgender identities, focusing on medical ethics and the importance of patient autonomy. Our guest, Kaitlyn Brown, discusses their advocacy for the intersex community, emphasizing the importance of trauma-informed care in healthcare settings. We talk about the differences between intersex and transgender identities, the prevalence of intersex conditions, and the challenges faced by parents of intersex children. The discussion highlights the complexity of genetic definitions and the need for better understanding and support within the healthcare system. It highlights the ongoing legislative challenges that threaten the rights and healthcare access of these communities, while also emphasizing the need for advocacy and allyship.

    Key Takeaways:

    • Intersex conditions encompass a wide range of biological variations.
    • Parents need support in navigating intersex diagnoses.
    • Genetic definitions of intersex are complex and varied.
    • Healthcare providers must approach intersex care with sensitivity.
    • Surgical interventions for intersex individuals are controversial and complex.
    • Patient autonomy is crucial in medical decisions regarding gender assignment.
    • Legislation is increasingly targeting transgender and intersex communities.
    • Inclusive conversations about sex and gender are essential in healthcare.
    • Cisgender individuals can use their privilege to advocate for intersex and transgender rights.

    Kaitlyn Brown is a certified genetic counselor from New Zealand who is endosex and identifies as a genderqueer femme, assigned female at birth. Currently a laboratory genetic counselor specializing in cell-free DNA prenatal screening, Kaitlyn has been an active advocate for the intersex community/ people with differences of sexual development and assisted in care management as a former pediatric genetic counselor and researcher. They have been involved with passing government initiatives to legislate awareness and understanding of differences of sex development for healthcare professionals and others who care for this community. Given the history of harmful practices performed on intersex and gender diverse people, Kaitlyn uses a trauma-informed lens to educate about sex development and incorporate both sex- and gender- diverse experiences and needs. They can be found on Bluesky as geneticsbtb.bsky.social

    Please subscribe to this podcast on Apple Podcasts, Spotify, YouTube or wherever you get your podcasts to stay updated on new episodes of All Access DNA. Listen to past episodes on your favorite podcast play by searching “All Access DNA” or by streaming from our website at allaccessdna.podbean.com

    Here are more resources related to today’s topic, genetic counselors.

    • InterACT- Advocates for Intersex Youth
    • Sambia culture of Papua New Guinea and “turnim-man”
    • Trauma Informed Care
    • Intersex Justice Project
    • Strategy Lab for Intersex Movements (SLIM)
    • InterConnect Support
    • Tested podcast about sex testing in elite sports from NPR
    • Book, Sex Itself by Sarah S Richardson

    Any inquiries on the podcast can be sent to AllAccessDNA@gmail.com

    Note that this podcast is for entertainment and education and is not intended to be a substitute for professional medical advice. Please consult your physician with any questions you may have regarding your health.

    The All Access DNA team includes: host, producer and editor Kate Wilson. The logo is designed by Designs by NKJ.

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    59 mins
  • Unraveling Justice: Dr. Henry Ehrlich and the DNA Revolution
    May 13 2025

    We are featuring an episode from another podcast on Gene Pool Media, DNA Today. True crime dominates the podcasting world, but what about the genetic aspects behind these cases? In this episode of DNA Today, we dive into the pivotal role of DNA in forensic science with Dr. Henry Erlich, a pioneer in DNA analysis and a key figure in developing polymerase chain reaction (PCR) technology. His work has transformed the criminal justice system, from solving cases to overturning wrongful convictions.

    Dr. Henry Erlich has authored over 450 publications and spent decades applying DNA analysis to criminal investigations, missing persons cases, and ancestry research. His lab performed the first DNA case in the US and, in 1988, the first DNA exoneration. Erlich was the Director of the Department of Human Genetics and Vice-President of Discovery Research for Roche Molecular Systems, Inc until 2013. He is currently a Senior Scientist at Benioff Children’s Hospital Oakland Research Institute.

    After reading his book Genetic Reconstruction of the Past, I had countless questions about how PCR reshaped the justice system, its impact on exonerations, and the ethical implications of forensic DNA databases.

    Trigger Warning: This episode contains discussions of murder and sexual assault, which may not be suitable for young listeners.

    Key Takeaways:

    • The development of PCR technology and its revolutionary impact on forensic genetics

    • How PCR outperformed older methods like RFLP in criminal case investigations

    • Pennsylvania vs. Pestinikas (1986), the first criminal case using DNA analysis

    • Key forensic DNA terms explained: inclusion, match, exclusion, and random match probability

    • The role of DNA evidence in exonerations and wrongful convictions

    • How forensic labs analyze DNA from multiple individuals at crime scenes

    • The establishment of the FBI’s National DNA Index System (NDIS) and who is included

    • The ethical concerns surrounding partial DNA matches and familial searching

    • How public DNA databases like GEDmatch helped identify the Golden State Killer

    • Dr. Erlich’s insights into the O.J. Simpson case and its impact on public perception of forensic DNA

    Resources and Links:

    • Read Genetic Reconstruction of the Past by Dr. Henry Erlich
    • Explore the National DNA Index System (NDIS) and CODIS
    • The Innocence Project: Fighting wrongful convictions with DNA evidence
    • GEDmatch and its role in forensic investigations

    Please subscribe to All Access DNA and DNA Today on Apple Podcasts, Spotify, YouTube or wherever you get your podcasts to stay updated on new episodes. Listen to past episodes on your favorite podcast play by searching “All Access DNA” or by streaming from our website at allaccessdna.podbean.com

    Check out our Patreon at patreon.com/allaccessdna and consider donating to get bonus content, submit questions for our guests, and connect with other genetic-curious individuals.

    Any inquiries on the podcast can be sent to AllAccessDNA@gmail.com

    Note that this podcast is for entertainment and education and is not intended to be a substitute for professional medical advice. Please consult your physician with any questions you may have regarding your health.

    DNA Today is hosted and produced by Kira Dineen, MS, LCGC, CG(ASCP)CM . Our Video Lead is Amanda Andreoli. Our Social Media Lead is Kajal Patel. Our Outreach Intern is Liv Davidson. And our logo Graphic Designer is Ashlyn Enokian, MS, CGC. The All Access DNA team includes: host, producer and editor Kate Wilson. The logo is designed by Designs by NKJ.

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    47 mins
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