Carbamazepine Podcast By  cover art

Carbamazepine

Carbamazepine

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  • Trade: Tegretol 
  • Class:  Anticonvulsant 
  • MOA: Binds preferably to voltage gated Sodium channels in their inactive conformation, which prevents repetitive and sustained firing of an action potential.
  • Indications: Partial and generalized tonic – clonic seizures 
  • Contraindications: AV Block, bundle branch block, agranulocytosis, bone marrow supression, monoamine oxidase inhibitor therapy
  • Side effects: Dizziness, drowsiness, ataxia, N/V, blurred vision, confusion, headache, transient diplopia, visual hallucinations, life threatening rashes.
  • Dosing:

Adult:

200mg PO

Pediatric:

6-12 years old: 100mg PO

        Less then 6: 10mg/kg PO


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