Episodes

  • Saunas, Pot, and Sleep Deprivation: The Unexpected Sperm Saboteurs in Your Life with Urologist Dr. Paul Turek
    Mar 6 2025

    Today we’re joined by Urologist and Microsurgeon Dr. Turek, internationally recognized as the authority on male fertility and sexual health. He is the founder of The Turek Clinic, is former endowed chair professor of the University of California, San Francisco, and inventor of sperm mapping for the treatment of severe male infertility. As a master microsurgeon, he popularized the no scalpel vasectomy and has among the highest published vasectomy reversal success rates.

    Dr. Turek's influence extends well beyond the clinic doors. His career has been dedicated to reshaping how we talk about men's health. This commitment is evident through his numerous research publications, global talks, and notable accolades, including a special invitation to the White House, as well as a prestigious NIH grant, and as an advisor to the NIH and Centers forDisease Control and Prevention.

    Join us as Dr. Turek discusses the most important factors contributing to male fertility, how to improve sperm health, how sperm changes as a man ages, and why sperm matter far more than we realize.

    Learn more about Dr. Turek and The Turek Clinic: https://www.theturekclinic.com/


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    58 mins
  • How Fidji Simo went from a tiny fishing village in France to CEO of multi-billion dollar tech company, Instacart, and the board of OpenAI
    Feb 27 2025

    Today’s guest is Fidji Simo, CEO and Chair of Instacart. Before Instacart, Fidji was the Vice President and Head of Facebook. She currently serves on the Board of Directors at OpenAI and Shopify. She co-founded the Metrodora Institute, a health center and research institute specializing in treating complex medical conditions, and is the president of The Metrodora Foundation.

    Fidji and I discuss her journey from growing up in a small town in France and being the first in her family to graduate high school, to being the CEO of a multi-billion dollar public company. She explains her strategic vision for Instacart, how to get the best advice from your Board of Directors, and how she’s navigated her own chronic condition alongside a fast-growing career.

    You can learn more about and support the Metrodora Institute here:
    https://www.metrodora.co/

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    53 mins
  • How Sam D’Amico, CEO of Impulse Labs, broke into the appliance tech industry and built the most powerful and precise stove ever
    Feb 20 2025

    Today I am joined by Sam D’Amico, Founder and CEO of Impulse Labs. Sam and his team have created the Impulse Cooktop- the most powerful and precise stove ever made due to its integrated battery, which doubles as a grid scale energy solution.

    Sam and I discuss his long history working on hardware related technology like AR and VR headsets with Google Glass and Oculus, how he got the idea to revolutionize the stove, hardware company business models and supply chains, and his thoughts on how AI will shape the hardware world in the next 5 years. If you’re interested in cutting edge technology, hardware, or even cooking, you won’t want to miss this episode!

    You can learn more about Impulse Labs and Sam here:

    Website | Impulse Labs
    LinkedIn | Sam D’Amico


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    49 mins
  • 300M+ AI fund GP Sarah Guo, the youngest ever partner at Greylock, shares her musings on AI & parenting her three kids
    Feb 13 2025

    Today I am joined by Sarah Guo, founder of Conviction, a venture capital firm that makes early-stage investments in technology startups. She was previously a General Partner at Greylock.

    Sarah and I talk about the rapid advancement of AI technologies, where she sees valuable being created, and which areas may be oversaturated. She notes some of the challenges to come for AI firms as they reach physical, technological, and data processing limits, and shares her thoughts on the role of human productivity in the coming years as AI technologies become more prevalent in the workplace.We also discuss becoming a mom, her views on balancing work and parenting, her philosophical approach to raising young humans in the age of AI, and so much more.

    You can learn more about Sarah at her website:https://sarahguo.com/

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    48 mins
  • On becoming a co-founder, an angel investor, and family planning with Anrok CEO Michelle Valentine
    May 9 2024

    Today our guest is Michelle Valentine. She is the Co-founder and CEO at Anrok. We cover lots of ground, discussing her experience founding Anrok and how it compares to her prior career as an investor (with a few investing tips discussed). She also shares her experience using Orchid and how it was a critical part of her eventual path to parenthood.

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    27 mins
  • How IVF works, and how Genetic Testing and Fertility Extension will impact family building with Dr. Amber Cooper
    May 2 2024

    Today our guest is Dr. Amber Cooper. Dr. Cooper is Chief Medical Officer-Genomics and Laboratory Sciences, and Medical and IVF Practice Director at Kindbody in St. Louis. She is also one of Orchid's Medical Advisors. First she gives us a crash course on IVF and debunks a popular misconception about it. Then we talk about how egg quality changes over time, what egg freezing is, how many eggs someone should freeze based on how many babies they’d like, and what excites her about the future of IVF.

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    33 mins
  • How one IVF doctor helps her patients overcome infertility struggles, and shares her own personal fertility journey
    Apr 25 2024

    Today our guest is Dr. Roohi Jeelani. She is board certified Reproductive Endocrinologist and Infertility Specialist at Kindbody, and one of Orchid’s Medical Advisory Board members. Dr. Jeelani shares her path to becoming a fertility doctor, and how, due in part to her own PCOS diagnosis, she became the patient herself as she sought fertility treatments to have her first and third child. Dr. Jeelani also debunks myths surrounding birth control, miscarriages, and breastfeeding, and shares her advice for others on their fertility journey.

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    38 mins
  • How one couple used IVF and genetic screening to protect their child from hemophilia
    Apr 18 2024

    Today our guests are Brandon Schram & Aimee Gupta, who opted to use IVF and genetic screening to reduce their future child’s risk of hemophilia, a blood clotting condition that runs in Aimee’s family. They share their IVF journey, as well as how beneficial genetic testing became for them when they later discovered their daughter had a rare genetic mutation that was causing her to have seizures as an infant. We also talk about the stigma that IVF can have and how to overcome the common feeling of guilt for passing on genetic mutations to your children.

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    38 mins