Episodes

  • #335 Neanderthals, Denisovans, and Us: How DNA Reveals Evolution

    #335 Neanderthals, Denisovans, and Us: How DNA Reveals Evolution
    Apr 4 2025

    This conversation is a follow-up to Episode #326: How DNA Solves Crimes – The Forensic Science Behind True Crime, where we explored the role of DNA in forensic investigations including the infamous O.J. Simpson case. Dr. Henry Erlich returns to the show to talk about human ancestry and evolution.

    Dr. Henry Erlich has authored over 450 publications and spent decades applying DNA analysis to criminal investigations, missing persons cases, and ancestry research. His work has helped us trace human origins, understand genetic diversity, and uncover how DNA links us to Neanderthals and Denisovans. His lab performed the first DNA case in the US and, in 1988, the first DNA exoneration. Erlich was the Director of the Department of Human Genetics and Vice-President of Discovery Research for Roche Molecular Systems, Inc until 2013. He is currently a Senior Scientist at Benioff Children’s Hospital Oakland Research Institute.

    Topics Covered in This Episode:
    • How PCR revolutionized genetic research and our understanding of evolution
    • What genetic diversity within African populations tells us about human origins
    • Debunking myths about Mitochondrial Eve and human ancestry
    • The genetic connections between humans, Neanderthals, and Denisovans
    • How ancient DNA from medieval bones reshapes what we know about genetic bottlenecks
    • Insights from the Pangenome Project and its potential to improve our understanding of genetic variation
    Relevant Episodes:
    • #326: How DNA Solves Crimes – The Forensic Science Behind True Crime (First Episode with Dr. Henry Erlich)
    • #216 African American Ancestry with Nicka Smith
    • #117 Dr. Janina Jeff on African Genomes
    • #251 Diversifying Genetic Research with 23andMe (Explores African American Sequencing Project)
    • #182 Dr. Eric Green on the Complete Human Genome Project and Pan Genome Project
    Resources and Links:
    • Read Genetic Reconstruction of the Past by Dr. Henry Erlich
    • Explore the National DNA Index System (NDIS) and CODIS
    • The Innocence Project: Fighting wrongful convictions with DNA evidence
    • GEDmatch and its role in forensic investigations

    Get ready, genetic nerds—another brand-new episode of DNA Today drops next Friday! You can always count on us to deliver fresh content every Friday.

    While you wait, why not dive into our library of over 300 episodes? Binge them all on Apple Podcasts, Spotify, our website, or wherever you love to listen—just search “DNA Today.”

    Prefer watching? We’ve got you covered! For the past four years, we’ve been recording episodes with video, including some filmed at the iconic NBC Universal Stamford Studios. Check them out on our YouTube channel!

    DNA Today is hosted and produced by Kira Dineen, MS, LCGC, CG(ASCP)CM . Our Video Lead is Amanda Andreoli. Our Social Media Lead is Kajal Patel. Our Outreach Intern is Liv Davidson. And our logo Graphic Designer is Ashlyn Enokian, MS, CGC.

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    31 mins
  • #334 ACMG 2025 Recap

    #334 ACMG 2025 Recap
    Mar 24 2025
    To recap the American College of Medical Genetics (ACMG) held in Los Angeles, host Kira Dineen is joined by Karl Krahn. The conference ended Saturday so instead of waiting until Friday to share this episode we released it early. Through this conversation, Kira and Karl reflect on their first attendance at the ACMG conference. They share insights on the sessions and events they attended, highlighting the engaging discussions and expert panels that made the conference memorable. Kira gives shout outs to a bunch of listeners she met during the conference, so tune in to see if she mentioned your name! Karl Krahn is a genetic counselor who serves as a Clinical Analyst doing variant curations for exams and genomes at a genetic testing lab. Karl and Kira met as classmates at Sarah Lawrence College and graduated together in 2020. This is Karl Krahn’s return appearance on DNA Today, his first episode was six years ago on Episode #101 where we celebrated Match Day by providing advice on starting genetic counseling grad school. Sessions Highlighted: 2025 ACMG Foundation Awards and Presidential Plenary Session - Genetics in the Media - Entertainment, Public Entertainment, Public Education, Controversies and Ethical DilemmasChallenge The Experts - Pediatric and Prenatal Diagnostic Dilemmas (Rare Knowns and Unknowns)Diagnostic Dilemmas from the Undiagnosed Diseases Network Genetic Counseling Forum: Sexual and Reproductive Health Counseling for Individuals with Intellectual Disability The ACMG/AMP/CAP/ClinGen Standards for Sequence Variant Classification Navigating the Current Landscape in Prenatal Genetics - Coverage, Politics and Laboratory Practice Latest Updates in Infertility Care IVF, PGT, and Alabama Advocacy Takeaways The ACMG conference provided valuable insights for various genetic professionals including genetic counselors The opening session set a positive tone for the conferenceNetworking with peers and listeners was a rewarding experienceHealthy snacks and beverages contributed to a welcoming atmosphere.The 'Challenge the Experts' session was particularly engaging and humorous where geneticists showcased the thought processes of leading professionals in genetics.The importance of addressing current political issues in genetics Sexual health education is essential for individuals with intellectual disabilities and genetic counselors are well positioned to introduce these topics and resources. Updates to ACMG criteria aim to clarify variant classificationsLegislation can significantly impact infertility care and patient accessStigma surrounding infertility remains a challenge in healthcare Resources Mentioned Laura Hercher’s DNA Today episodes #284 IVF in Alabama #191 Overturn of Roe #157 Texas’ SB8Recent national genetic conference recaps: NSGC 2024 and ASHG 2024 Sexual and reproductive health resources for people with intellectual disabilities We are already looking forward to ACMG 2026 in Baltimore, and coincidentally the 2026 National Society of Genetic Counselors (NSGC) annual conference will also take place in Baltimore. It’s worth pointing out that the next NSGC conference is November 2025 in Seattle. And Kira misspoke, the next national genetics conference she will attend will be the American Society of Human Genetics (ASHG) which will be in Boston this Fall. See you all there! Get ready, genetic nerds—another brand-new episode of DNA Today drops this Friday! You can always count on us to deliver fresh content every Friday. While you wait, why not dive into our library of over 300 episodes? Binge them all on Apple Podcasts, Spotify, our website, or wherever you love to listen—just search “DNA Today.” Prefer watching? We’ve got you covered! For the past four years, we’ve been recording episodes with video, including some filmed at the iconic NBC Universal Stamford Studios. Check them out on our YouTube channel! DNA Today is hosted and produced by Kira Dineen, MS, LCGC, CG(ASCP)CM . Our Video Lead is Amanda Andreoli. Our Social Media Lead is Kajal Patel. Our Outreach Intern is Liv Davidson. And our logo Graphic Designer is Ashlyn Enokian, MS, CGC. See what else we are up to on Instagram, X (Twitter), BluSky, Threads, LinkedIn, Facebook, YouTube and our website, DNAToday.com. Questions/inquiries can be sent to info@DNAtoday.com.
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    32 mins
  • #333 Approaching a Down Syndrome Diagnosis with Care

    #333 Approaching a Down Syndrome Diagnosis with Care
    Mar 21 2025

    To celebrate World Down Syndrome Day (which is today March 21st, 2025) our host Kira Dineen sits down with Carissa Carroll, the founder of Jack’s Basket, a nonprofit dedicated to celebrating babies with Down syndrome and supporting their families. Inspired by her son Jack, Carissa launched Jack’s Basket to provide new parents with resources, encouragement, and community connections.

    In this heartfelt conversation, we explore:

    • The power of celebrating every baby with Down syndrome
    • How healthcare providers can deliver a diagnosis with compassion
    • The essential resources and support networks available for families
    • The profound impact of Jack’s Basket worldwide
    • The role of education and awareness in fostering inclusion

    Whether you’re a healthcare professional, a parent, or an advocate, this episode sheds light on the importance of positive, informed communication and the life-changing support of community organizations like Jack’s Basket.

    About Our Guest:

    Carissa Carroll is an alumna of Bethel University and the University of Minnesota. She taught at elementary and collegiate levels before a sweet baby boy named Jack changed her heart and passion. After an abrupt and assumptive diagnosis experience, Carissa felt led to start Jack’s Basket. She wanted to make a change for future parents, ensuring that they felt their child was a reason to celebrate and have opportunities to connect within the community. Carissa presents to medical professionals about how to deliver the diagnosis without bias, works with the Jack’s Basket board to further the mission, and connects with volunteers who deliver baskets.

    Jack’s Basket Resources:

    Request a Basket

    Genetic Counseling Webinar: "Communicating Unexpected News"

    Other DNA Today Episodes About Down Syndrome:

    #176 Glee's Lauren Potter on Down Syndrome Awareness

    #280 Celebrating Down Syndrome with Parent & Nurse Jenness Stock

    Get ready, genetic nerds—another brand-new episode of DNA Today drops this Friday! You can always count on us to deliver fresh content every Friday.

    While you wait, why not dive into our library of over 300 episodes? Binge them all on Apple Podcasts, Spotify, our website, or wherever you love to listen—just search “DNA Today.”

    Prefer watching? We’ve got you covered! For the past four years, we’ve been recording episodes with video, including some filmed at the iconic NBC Universal Stamford Studios. Check them out on our YouTube channel!

    DNA Today is hosted and produced by Kira Dineen, MS, LCGC, CG(ASCP)CM . Our Video Lead is Amanda Andreoli. Our Social Media Lead is Kajal Patel. Our Outreach Intern is Liv Davidson. And our logo Graphic Designer is Ashlyn Enokian, MS, CGC.

    See what else we are up to on Instagram, X (Twitter), BluSky, Threads, LinkedIn, Facebook, YouTube and our website, DNAToday.com. Questions/inquiries can be sent to info@DNAtoday.com.

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    36 mins
  • #332 Building Stronger Rare Disease Organizations: NORD CEO’s Insight

    #332 Building Stronger Rare Disease Organizations: NORD CEO’s Insight
    Mar 14 2025
    This week we attended the 2025 Connecticut Rare Disease Forum organized by BioCT and held at the beautiful Jackson Laboratory. This afternoon was filled with industry-led discussions on innovation in rare disease diagnostics and treatments, along with the promising impact of these advancements on patient outcomes. After the events wrapped, I caught up with Pamela Gavin, who serves as the President and CEO of the National Organization for Rare Disorders (NORD). She was on the panel, “Bringing Science to the Patient: Moving Upstream Toward Durable Response and Cures.” This in-person conversation explores the vital role of patient advocacy organizations, particularly NORD, in supporting individuals with rare diseases. It discusses the evolution of patient advocacy, the importance of genetic testing, and the need for a robust workforce in genetic counseling. We emphasize the significance of building effective organizations and learning from successful models to enhance the impact on rare disease communities. Takeaways NORD serves as a safe, trusted place for people to connect regarding rare diseases.Patient advocacy organizations play a crucial role in drug development and research.The landscape of patient advocacy has evolved significantly in recent years.Building effective rare disease organizations requires understanding best practices and community needs.Learning from successful organizations can help new groups avoid common pitfalls.Genetic testing is becoming increasingly important in diagnosing rare diseases.The future of genetic counseling faces challenges due to increasing diagnoses and limited workforce.Engaging the next generation in genetics is essential for the future of healthcare.Collaboration and communication within the rare disease community can lead to better outcomes.Advocacy organizations must adapt to the rapid advancements in genetic technology and testing. Our Guest Pamela Gavin was appointed chief executive officer of the National Organization for Rare Disorders (NORD®) in May 2024, becoming the third CEO in the organization’s 42-year history. Gavin’s deep connection to the rare disease community and extensive professional experience make her uniquely suited to lead NORD into its next chapter of innovation, advocacy and impact. Before joining NORD, she held several influential roles in healthcare innovation and safety, including as senior director, Strategic Business Initiatives at the University of Pittsburgh Medical Center, where she launched emerging technologies to improve healthcare delivery; government consultant responsible for developing the Federal Safety Reporting Portal for the NIH, FDA and other organizations; founder and executive of SafeCare Systems, a pioneer in safety management information systems; and division director at the Harvard Risk Management Foundation. Gavin holds a Master of Business Administration in Healthcare Management from Northeastern University and a bachelor’s degree from Smith College. DNA Today Episodes Referenced #147 CF Series: Bijal Trivedi on "Breath From Salt" #149 CF Series: Gunnar Esiason on Patient Advocacy #293 Smith-Magenis Syndrome with Parent Scotti Taylor There are countless episodes about rare diseases, many of which are captured in this YouTube playlist. Get involved with a rare disease organization here on NORD’s website. We’re honored to share that "DNA Today" has once again been recognized by Feedspot as one of the Top 10 DNA Podcasts, Top 25 Genetics Podcasts, and Top 70 Award-Winning Podcasts! Even more exciting? We continue to hold the Number 1 spot as the leading podcast about DNA! This achievement is thanks to our incredible guests, engaged listeners, and amazing supporters. Your enthusiasm for genetics and genomics keeps us inspired to bring you the latest discoveries, expert interviews, and meaningful stories. Thanks to Anuj Agarwal for continuing to recognize our podcast every year! Get ready, genetic nerds—another brand-new episode of DNA Today drops this Friday! You can always count on us to deliver fresh content every Friday. While you wait, why not dive into our library of over 300 episodes? Binge them all on Apple Podcasts, Spotify, our website, or wherever you love to listen—just search “DNA Today.” Prefer watching? We’ve got you covered! For the past four years, we’ve been recording episodes with video, including some filmed at the iconic NBC Universal Stamford Studios. Check them out on our YouTube channel! DNA Today is hosted and produced by Kira Dineen, MS, LCGC, CG(ASCP)CM . Our Video Lead is Amanda Andreoli. Our Social Media Lead is Kajal Patel. Our Outreach Intern is Liv Davidson. And our logo Graphic Designer is Ashlyn Enokian, MS, CGC. See what else we are up to on Instagram, X (Twitter), BluSky, Threads, LinkedIn, Facebook, YouTube and our website, DNAToday.com. Questions/inquiries can be sent to info@DNAtoday.com.
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    30 mins
  • #331 Pediatric Mock Genetic Counseling Session: Autism and Developmental Delay

    #331 Pediatric Mock Genetic Counseling Session: Autism and Developmental Delay
    Mar 7 2025
    This is our third installment in our new Mock Genetic Counseling Session Series! In this episode, pediatric genetic counselor Miranda Di Biase and students Claire Zimlinghaus and Joy Lin perform a mock pediatric genetic counseling session. This session’s indication is one of the most common in pediatric genetics: autism. This session was recorded in person, providing a more dynamic and engaging learning experience therefore, we highly recommend watching it on YouTube to fully immerse yourself in the interaction. We hope this series is helpful for prospective and current genetic counseling students, as well as the general public, by demystifying the genetic counseling process. Understanding how these sessions work can empower individuals and provide valuable educational insights into this critical healthcare service. The Actors: Miranda Di Biase, MS, CGC, is a Pediatric Genetic Counselor at the Children's Hospital at Montefiore Einstein. Her clinical focus centers on counseling families on genetic testing options to find a potential genetic etiology for their child's medical concerns. Di Biase also specializes in pediatric cancer predisposition syndromes and Williams syndrome. Di Biase's research focuses on genome sequencing. She participated in the NYCKidSeq research study, which performed whole genome sequencing for patients with neurological, immune and/or cardiac health problems. Her work has been shared through numerous scientific publications and abstracts. After obtaining her Bachelor of Science from York University in Toronto, Canada, Di Biase moved to New York to earn her Master of Human Genetics at Sarah Lawrence College. Di Biase is certified by the American Board of Genetic Counseling and was nominated for the prestigious Heart of Genetic Counseling award in 2021 presented by the National Society of Genetic Counselors and Invitae. This award honors genetic counselors who have made a difference in the lives of their patients by using the combination of human excellence and human compassion that defines the profession. Claire Zimlinghaus is a second year graduate student at the Sarah Lawrence College Joan H. Marks Human Genetics program. She received a Bachelor's degree in Biological Sciences from the University of Pittsburgh in 2023. Claire has had a passion for the science of genetics since her youth, and hopes to be a source of information and empathy for her patients as a genetic counselor. Joy Lin is currently a second year genetic counseling student in the Joan H. Marks Graduate Program in Human Genetics at Sarah Lawrence College. She received her Bachelor of Science in Biochemistry and Psychology from Stony Brook University. She is passionate about genetics and hopes to provide meaningful care to individuals and families as a genetic counselor. Pediatric Mock Session Case Information Case Details: The patient is a 4 year old male with autism and global developmental delay who presented to genetics with his mother and sister-in-law. Patient Name: John Parent Name: Claire Sister-in-law Name: Joy Medical History: Pregnancy:Uncomplicated Non-invasive prenatal screening: low risk for trisomiesUltrasounds were normalFull term via NSVDExposures: none Developmental milestones: delayedSitting: 10 monthsWalking: 2 yearsTalking: 3 yearsCan speak in 2-3 word sentences EducationPreschool TherapiesOT (2x weekly, 30 min)ST (2x weekly, 30 min)PT (2x weekly, 30 min) Review of SystemsENT - ear infections (3x)Normal physical exam Specialists seen:Neurologist, Audiologist, Developmental Pediatrician Family History: Ancestry: Irish and GermanNo consanguinity, birth defects, genetic conditions, multiple miscarriages or infant deathsCousin with autism Pediatric Mock Session Outline Contracting: Greetings and introductionsReason for referral to genetic counselingOverview of sessionAddress patient questions or concerns Medical Intake: Pregnancy history, developmental milestones, review of systems, and other relevant medical history Family History: Construct a pedigreeConsanguinity, ID/DD/autism, birth defects, genetic conditions, multiple miscarriages, infant deaths, etc. Physical Examination Done by the geneticist Patient Education Overview of geneticsCauses of autism spectrum disorderDiscussion of multifactorial causes, chromosomal abnormalities, single-gene disorders Discuss appropriate testing options:Chromosomal microarray + Fragile X syndrome testingWhole exome sequencing (WES)Whole genome sequencing if indicated Sample collections blood versus saliva Possible resultsNegative, Positive, Variant of Uncertain SignificanceIncidental findingsSecondary findings can be reported for ES and GS Turnaround timeCost and insurance coverageShared decision-makingInformed consent Recommendations and next steps Summary of the sessionFollow up with genetic counseling to discuss test results Final questions and conclusion of session...
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    54 mins
  • #330 Rare Disease Parenting: A 7-Year Diagnostic Odyssey to Wiedemann-Steiner Syndrome

    #330 Rare Disease Parenting: A 7-Year Diagnostic Odyssey to Wiedemann-Steiner Syndrome
    Feb 28 2025

    Happy Rare Disease Day! We are celebrating by shining a light on Wiedemann-Steiner Syndrome (WSS), which is a rare genetic condition that affects development, growth, and overall health.

    Joining us are Caleb and Abbi Wahl, parents to two daughters, one of whom, Jenni Anne, was diagnosed with WSS after a seven-year diagnostic odyssey.

    They share: 🧬 Early signs & the long road to diagnosis 💡 How they processed & adapted to the diagnosis 🤝 Resources & the support that made a difference 📢 Their advocacy work & the power of the WSS community

    Resources:

    Team IMPACT

    Uplifting Athletes

    WSS Foundation

    National Organization for Rare Disorders

    Get ready, genetic nerds—another brand-new episode of DNA Today drops this Friday! You can always count on us to deliver fresh content every Friday.

    While you wait, why not dive into our library of over 300 episodes? Binge them all on Apple Podcasts, Spotify, our website, or wherever you love to listen—just search “DNA Today.”

    Prefer watching? We’ve got you covered! For the past four years, we’ve been recording episodes with video, including some filmed at the iconic NBC Universal Stamford Studios. Check them out on our YouTube channel!

    DNA Today is hosted and produced by Kira Dineen, MS, LCGC, CG(ASCP)CM . Our Video Lead is Amanda Andreoli. Our Social Media Lead is Kajal Patel. Our Outreach Intern is Liv Davidson. And our logo Graphic Designer is Ashlyn Enokian, MS, CGC.

    See what else we are up to on Instagram, X (Twitter), BluSky, Threads, LinkedIn, Facebook, YouTube and our website, DNAToday.com. Questions/inquiries can be sent to info@DNAtoday.com.

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    32 mins
  • #329 Preventive Genomic Medicine: Saving Lives and Healthcare Costs with MyOme

    #329 Preventive Genomic Medicine: Saving Lives and Healthcare Costs with MyOme
    Feb 21 2025

    How can preventive genomic medicine save $200 billion annually in healthcare costs? Dr. Matthew Rabinowitz breaks it down in this episode.

    Dr. Rabinowitz—a true pioneer in genetics, diagnostics, and AI—who’s been at the forefront of transforming how we approach health and medicine. Dr. Rabinowitz isn’t just a scientist; he’s a visionary who’s helped create groundbreaking technologies, from revolutionizing pregnancy care to tracking cancer through blood tests. In 2024, he was named R&D Leader of the Year by R&D World. Now, he’s tackling preventative genomic medicine, showing us how tools like whole genome sequencing (WGS) and polygenic risk scores (PRS) are turning healthcare from reactive to proactive.

    Dr. Rabinowitz is the co-founder and Executive Chairman of MyOme and has played a key role in developing cutting-edge genomic technologies. His work has shaped the fields of reproductive genetics, cancer diagnostics, and precision medicine. With over 100 patents and publications, including papers in Science and Nature, his impact on healthcare is undeniable.

    Topics Covered:
    • How whole genome sequencing (WGS) is reshaping healthcare and risk assessment
    • The power of polygenic risk scores (PRS) in cancer prevention and early detection
    • MyOme’s Breast Cancer Polygenic Risk Score (PRS) and its implications for proactive medicine
    • The economic benefits of genomic medicine in early intervention and disease prevention include potentially saving $200 billion annually in healthcare costs
    • Ethical considerations and the importance of inclusivity in genomic research
    • The future of preventive genomic medicine—will WGS become standard care? Will it start with newborns?
    Resources and Links:
    • Learn more about MyOme and its work in preventive genomic medicine: myome.com

    Get ready, genetic nerds—another brand-new episode of DNA Today drops this Friday! You can always count on us to deliver fresh content every Friday.

    While you wait, why not dive into our library of over 300 episodes? Binge them all on Apple Podcasts, Spotify, our website, or wherever you love to listen—just search “DNA Today.”

    Prefer watching? We’ve got you covered! For the past four years, we’ve been recording episodes with video, including some filmed at the iconic NBC Universal Stamford Studios. Check them out on our YouTube channel!

    DNA Today is hosted and produced by Kira Dineen, MS, LCGC, CG(ASCP)CM . Our Video Lead is Amanda Andreoli. Our Social Media Lead is Kajal Patel. Our Outreach Intern is Liv Davidson. And our logo Graphic Designer is Ashlyn Enokian, MS, CGC.

    See what else we are up to on Instagram, X (Twitter), BluSky, Threads, LinkedIn, Facebook, YouTube and our website, DNAToday.com. Questions/inquiries can be sent to info@DNAtoday.com.

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    35 mins
  • #328 Breakthrough Biotech: CAR-Ts for Solid Tumors & Engineered Bacteria for Rare Diseases

    #328 Breakthrough Biotech: CAR-Ts for Solid Tumors & Engineered Bacteria for Rare Diseases
    Feb 14 2025
    This week, I attended BIO’s CEO and Investor Conference in New York City—one of the largest investor gatherings in the biotech industry. The conference, organized by BIO (Biotechnology Innovation Organization), brings together institutional investors, industry analysts, and senior executives to discuss the latest biotech advancements and investment opportunities. At the conference, I attended insightful panel discussions and company presentations where biotech CEOs shared their latest breakthroughs, research progress, and investment potential. After their presentations, I had the chance to sit down with two biotech leaders to dive deeper into their work: Dr. Premal Patel of Cellinfinity Bio and Dr. Travis Whitfill of Azitra. Guest Bios: Dr. Premal Patel A physician-scientist with 15 years of experience in medical oncology drug development, Dr. Patel has worked with major biotech companies like Genentech, Pfizer, and Juno Therapeutics. He specializes in CAR-T therapy, a groundbreaking approach to engineering immune cells to fight cancer. Now, as CEO of Cellinfinity Bio, he’s focused on tackling one of cancer treatment’s biggest challenges: using CAR-T to treat solid tumors. Dr. Travis Whitfill A serial biotech entrepreneur and venture capitalist, Dr. Whitfill co-founded Azitra, a company pioneering the use of synthetic biology to engineer skin bacteria for treating rare genetic skin diseases. He has led multiple biotech startups, served on the boards of several healthcare companies, and was named to Forbes’ 30 Under 30 (Healthcare) list in 2018. Interview Highlights: Dr. Premal Patel – CAR-T Therapy for Solid Tumors CAR-T cell therapy has revolutionized blood cancer treatment, but treating solid tumors remains a major challenge.Dr. Patel explains how Cellinfinity Bio is re-engineering T cells to overcome the barriers posed by solid tumors, making them more effective at infiltrating and attacking cancer cells.His team’s gene engineering approach aims to make CAR-T therapy more accessible and affordable, potentially bringing costs down to the range of antibody-based treatments.The ultimate goal: a game-changing, in-body T-cell reprogramming approach that could expand access to CAR-T therapies globally. Dr. Travis Whitfill – Engineering Skin Bacteria for Rare Diseases Azitra is developing synthetic biology solutions for rare genetic skin diseases, like Netherton syndrome, which currently has no FDA-approved treatments.Their novel therapy aims to treat skin rashes in cancer patients taking EGFR inhibitor drugs, reducing the need for high-dose antibiotics and steroids.Genetically modified bacteria (Staphylococcus epidermidis) are used to deliver missing proteins directly to the skin, a groundbreaking approach in dermatology and rare disease treatment.By integrating precision genetic engineering with synthetic amino acid control, Azitra ensures the therapy is both effective and safe. Resources & Links: Learn more about BIO’s CEO & Investor Conference hereExplore Cellinfinity Bio’s CAR-T research hereDiscover Azitra’s work in synthetic biology here Get ready, genetic nerds—another brand-new episode of DNA Today drops this Friday! You can always count on us to deliver fresh content every Friday. While you wait, why not dive into our library of over 300 episodes? Binge them all on Apple Podcasts, Spotify, our website, or wherever you love to listen—just search “DNA Today.” Prefer watching? We’ve got you covered! For the past four years, we’ve been recording episodes with video, including some filmed at the iconic NBC Universal Stamford Studios. Check them out on our YouTube channel! DNA Today is hosted and produced by Kira Dineen, MS, LCGC, CG(ASCP)CM . Our Video Lead is Amanda Andreoli. Our Social Media Lead is Kajal Patel. Our Outreach Intern is Liv Davidson. And our logo Graphic Designer is Ashlyn Enokian, MS, CGC. See what else we are up to on Instagram, X (Twitter), BluSky, Threads, LinkedIn, Facebook, YouTube and our website, DNAToday.com. Questions/inquiries can be sent to info@DNAtoday.com.
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    30 mins