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Dhru Purohit Show

Dhru Purohit Show

By: Dhru Purohit
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 Hi, I'm Dhru (like Drew), and every week, I interview the top experts in health, medicine, and mindset to provide you with in-depth, step-by-step protocols to take your health to the next level.Dhru Purohit Show 2024 Alternative & Complementary Medicine Hygiene & Healthy Living Physical Illness & Disease
Episodes
  • Why Excess Added Sugar is Driving Modern Diseases and How to Take Back Our Metabolic Health and Overcome a Sedentary Lifestyle

    Why Excess Added Sugar is Driving Modern Diseases and How to Take Back Our Metabolic Health and Overcome a Sedentary Lifestyle
    Jun 2 2025
    This episode is brought to you by Cozy Earth and Ollie. Sugar is everywhere in the modern diet, and it's silently driving a massive wave of chronic illness. From insulin resistance and fatty liver to cognitive decline, the overconsumption of ultra-processed, sugar-laden foods has created a health crisis hiding in plain sight. As scientists uncover deeper connections between sugar, metabolism, and brain health, one thing is clear: this isn’t just about cutting calories—it’s about changing the way we eat to protect our long-term well-being. Today on The Dhru Purohit Show, we’re bringing you a special compilation episode featuring Dhru’s conversations with top experts on the connection between insulin resistance, fatty liver, and Alzheimer’s disease. Dr. Robert Lustig shares the impact of added sugar on mitochondrial health and metabolism. He also discusses what you can expect when significantly reducing the amount of added sugar in your diet, why the quality of your calories matters, and the fascinating ways our bodies store fat. Dr. Richard Johnson discusses his revolutionary new hypothesis on the link between fructose consumption and Alzheimer’s disease. Dhru and Dr. Johnson discuss the evolutionary mechanism behind fructose metabolism, insulin resistance, and weight gain, which has backfired due to its overconsumption. In this episode, Dhru and his guests dive into: What is leptin resistance (2:11) Thin on the outside, fat on the inside (TOFI) (5:55) The three sites of fat deposition in the body (6:47) Key findings from the SHINE study (17:03) The Metabolic Matrix: feed the gut, protect the liver, and support the brain (21:35) Dr. Johnson’s hypothesis on the link between Alzheimer’s and fructose consumption (25:05) The origins of Alzheimer’s: what’s happening in the brain (33:28) Uric acid as a driver of fat accumulation, and its connection to gout, obesity, and other diseases (31:13) The relationship between salt, dehydration, and fructose production (45:51) How fructose increases our cravings for sugar (50:01) The role of fructose in Alzheimer’s disease (56:56) Also mentioned: Full episode with Dr. Robert Lustig Full episode with Dr. Richard Johnson This episode is brought to you by Cozy Earth and Ollie. Right now, get 40% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP. Want to give your dog the best in clean eating? Take the online quiz and introduce Ollie to your pet. Right now, Ollie is offering 60% off your first box of meals when you subscribe today! Just head to Ollie.com, use the code DHRU, and you’ll get 60% off your first box of meals in your subscription.Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 hr and 13 mins
  • Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

    Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)
    May 28 2025
    This episode is brought to you by Momentous, Levels, and Branch Basics. Alzheimer’s doesn’t begin at diagnosis—it starts decades earlier. That means the choices we make right now can have a major impact on our brain health down the line. But with so much conflicting health advice out there, how do you know what really moves the needle? Today’s guest cuts through the noise and shares the most effective, science-backed strategies to protect your brain, no matter your age. Today on The Dhru Purohit Show, we’re revisiting one of our favorite episodes with neurophysiologist Louisa Nicola. Louisa shares the top three lifestyle factors that can influence our risk for Alzheimer’s disease. She helps us sort through the most current research and uncovers the biggest myths. She also shares the top two supplements that are critical for protecting brain health and the optimal prescription for exercise and resistance training. Looking to protect your brain health? Louisa shows us how. Louisa Nicola, an Australian-born neurophysiologist and sports scientist, has made significant strides in the field of brain performance and human potential. In 2016, she founded Neuro Athletics, a consulting firm dedicated to optimizing brain health and performance for athletes, executives, and high performers. Louisa's innovative methods improve reaction times, decision-making, and mental acuity. Her vision is to expand Neuro Athletics' reach, empowering more individuals to achieve their full potential through enhanced brain function and mental resilience. In this episode, Dhru and Louisa dive into: The alarming increase in Alzheimer's disease despite genetics (00:33) Why sleep is a critical factor in preventing disease (2:43) The impact of a sedentary lifestyle on increasing your risk for Alzheimer’s disease and tips for beginners (17:47) Physiology as we age (34:35) Fundamental pillars of nutrition and the power of Omega-3 fatty acids (42:20) Creatine for neuroprotection, energy, and reversing osteoporosis (54:02) The biggest myth about Alzheimer’s disease (01:02:51) What motivated Louisa to study Alzheimer’s disease (01:05:44) Actionable steps you can implement to reduce your risk (01:08:50) Implementing sauna into your routine to induce good stress (01:12:13) Brain optimization beyond the fundamentals (01:15:12) Social connections that power health (01:23:18) Bigger muscles-better brain health (01:31:20) Also mentioned in this episode: Omega Quant Test Neuroathletics Instagram Sleep Regularity as a Predictor of All-Cause Mortality Study For more on Louisa, follow her on Instagram, Twitter, and YouTube, or visit her Website. This episode is brought to you by Momentous, Levels, and Branch Basics. Optimize your energy and mental clarity with the Momentous Three: Protein, Omega-3s, and Creatine made by and used by the best. Head to livemomentous.com and use code DHRU for 35% off your first subscription. Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link: levels.link/DHRU. Make moves on your metabolic health with Levels today. Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use coupon code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
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    1 hr and 46 mins
  • The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

    The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy
    May 26 2025
    This episode is brought to you by Square, Branch Basics, and Manukora Honey. When we’re told our labs are “normal,” that doesn’t always mean they’re optimal—especially considering that over one-third of Americans are prediabetic and 47 million have metabolic syndrome. Metabolic health is the foundation of true longevity. Without actively supporting it, the risk of chronic diseases like cardiovascular disease, cancer, and type 2 diabetes increases. The good news? Prioritizing metabolic health through simple lifestyle changes can lead to long-term vitality and meaningful transformation. Today on The Dhru Purohit Show, we’re bringing you a special compilation episode featuring Dhru’s conversations with top experts on the most underrated blood tests for metabolic health and how to decode optimal lab markers. Dr. Tyna Moore breaks down the science behind metabolic dysfunction and its connection to chronic disease. She shares the essential labs to order, how often to test, and what optimal results should look like. She also offers practical tips for beginners on getting started with resistance training. Dr. Ben Bikman dives into how elevated fasting insulin contributes to insulin resistance, fat storage, and challenges in sustainable weight loss. He also explores how genetics play a role in weight gain and why lowering insulin—not just counting calories—should be the first step in any effective weight-loss strategy. Dr. Tyna Moore is a board-certified naturopathic and chiropractic physician and the founder and owner of Core Wellness Clinic in Portland, Oregon. She specializes in non-surgical pain management, natural pain solutions, and regenerative injection therapies for orthopedic and musculoskeletal conditions. Dr. Ben Bikman is a metabolic research scientist and author of Why We Get Sick, which explores insulin resistance as a root cause of many chronic health issues. With a PhD in bioenergetics and postdoctoral work in metabolic disorders, he now serves as an associate professor at BYU, where he studies insulin’s role in obesity, diabetes, and mitochondrial health. In this episode, Dhru and his guests dive into: Metabolic health and disease pathways (2:10) Key lab tests and optimal levels (4:25) How and why to start resistance training (20:49) The most underrated blood test for metabolic health (33:57) Optimal reference ranges for fasting insulin (37:45) The two primary factors contributing to weight gain (44:22) The role of fat cells and ethnic differences (53:09) Final thoughts (1:01:34) Also mentioned: Full episode with Dr. Tyna Moore Full episode with Dr. Ben Bikman Want Dhru’s Lab Ranges Cheat Sheet? Sign up for the Try This Newsletter and we’ll send it straight to your inbox! This episode is brought to you by Square, Branch Basics, and Manukora Honey. Get everything you need to run and grow your business, without any long-term commitments with Square. Right now, you can get up to $200 off Square hardware at square.com/go/DHRU Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use coupon code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics! Upgrade to the creamiest honey, packed with antioxidants and prebiotics. Just go to manukora.com/dhru to get $25 off the Starter Kit and boost your energy, immunity, and digestive health today! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices
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    59 mins
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All stars
Most relevant  
Commentary that is stimulating and thought provoking. A wonderful show to listen to with a variety of topics. I appreciate the dialog between Dhru and the guest being spontaneous vs overly scripted.

Intelligent, educational, and stimulating

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Dhru respects his guests, allowing enough space for answering. Great choice of guests. Love this podcast.

Great interviews

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Great information shared in a balanced way in an easy to understand method. Provides insights on how to modify diets to improve health.

Great actionable Information!

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