Drs Matteo Bassetti and Tobias Welte discuss highlights in the treatment of patients with COVID-19, including a discussion of antivirals, corticosteroids, monoclonal antibodies, and what lies ahead for future treatment options.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/989640). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for healthcare professionals.

Resources

Coronavirus Disease 2019 (COVID-19) Treatment & Management https://emedicine.medscape.com/article/2500114-treatment

Anti-CD20 Monoclonal Antibody TL011 https://www.cancer.gov/publications/dictionaries/cancer-drug/def/anti-cd20-monoclonal-antibody-tl011

Rituximab (Rx) https://reference.medscape.com/drug/rituxan-truxima-rituximab-342243

Coronavirus Disease 2019 (COVID-19) https://emedicine.medscape.com/article/2500114-overview

SARS-CoV-2 Variants https://www.idsociety.org/covid-19-real-time-learning-network/emerging-variants/emerging-covid-19-variants/

Not Just Antibodies: B Cells and T Cells Mediate Immunity to COVID-19 https://pubmed.ncbi.nlm.nih.gov/32839569/

Antivirals, Including Antibody Products https://www.covid19treatmentguidelines.nih.gov/therapies/antivirals-including-antibody-products/

Hydrocortisone in Severe Community-acquired Pneumonia https://pubmed.ncbi.nlm.nih.gov/36942789/

Molnupiravir (Investigational) https://reference.medscape.com/drug/lagevrio-molnupiravir-4000252

Nirmatrelvir/ritonavir (Rx) https://reference.medscape.com/drug/paxlovid-nirmatrelvir-ritonavir-4000259

Remdesivir (Rx) https://reference.medscape.com/drug/veklury-remdesivir-4000090

Anti-SARS-CoV-2 Monoclonal Antibodies https://www.covid19treatmentguidelines.nih.gov/therapies/antivirals-including-antibody-products/anti-sars-cov-2-monoclonal-antibodies/

Considerations for SARS-CoV-2 Antigen Testing for Healthcare Providers Testing Individuals in the Community https://www.cdc.gov/coronavirus/2019-ncov/lab/resources/antigen-tests-guidelines.html