Hydroxocobalamin
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Hydroxocobalamin
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About this listen
- Trade – Cyanokit
- MOA: Antidote, cyanide poisoning adjunct Binds with cyanide to form nontoxic cyanocobalamin, preventing its toxic effects; excreted renally
- Indications: Treatment of known or suspected cyanide poisioning.
- Contraindications: None is the emergency setting
- Side Effects: Hypertension, allergic reactions, GI bleeding, nausea, vomiting, dyspepsia, dyspnea, dizziness, headache, injection site reactions.
- Dosage:
Adult: 5 g IV infusion over 15 minutes at a rate of 15 mL/min.
Pedi: 70 mg/kg IV one time, may be repeated one time at the same dose.
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