Lean By Design Podcast By Oscar Gonzalez & Lawrence Wong cover art

Lean By Design

Lean By Design

By: Oscar Gonzalez & Lawrence Wong
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About this listen

Lean by Design delves into the dynamic world of biotech, pharma, and life sciences, focusing on operational excellence through effective workflow and process optimization. Join hosts Oscar Gonzalez and Lawrence Wong as they engage with industry leaders who share their insights, innovative strategies, and real-world experiences in transforming complex challenges into streamlined, efficient solutions. Through thought-provoking conversations, you’ll gain practical tips and inspiration to drive continuous improvement and success in your organization. Produced by Sigma Lab Consulting, Lean by Design empowers you to enhance productivity and innovation, one process at a time. Listen on Spotify, iTunes, Apple Podcasts, or wherever you get your podcasts.

© 2025 Lean By Design
Economics Management Management & Leadership Science
Episodes
  • 0204. Start With the End: How PRFAQs Create Clarity Before You Build with Marcelo Calbucci
    Jun 11 2025

    Send us a text

    Have you ever started a project only to realize you’re building something your leaders never asked for? You’re not alone.

    In this episode of Lean by Design, we sit down with Marcelo Calbucci, a veteran of Amazon, Microsoft, and multiple startups, to explore the PRFAQ Framework, Amazon’s secret weapon for aligning strategy and execution.

    By drafting a mock press release and FAQ before a single line of code is written, teams force themselves to clarify vision, spot roadblocks, and reach consensus across departments. The real magic comes from the collaborative review and no bullet‑filled slides, just a tight narrative that surfaces gaps in logic and focuses on solving genuine customer problems.

    Whether you’re battling scope creep as a product manager or aiming for alignment as an executive, this conversation will equip you with a powerful tool to kick off your next project with crystal‑clear purpose. Tune in and learn to work backward for forward momentum.

    Learn more about the PRFAQ at https://www.theprfaq.com/

    Connect with Marcelo at https://www.linkedin.com/in/marcelocalbucci | https://x.com/calbucci

    Ready to assess your organization’s efficiency? Connect with us at leanbydesign@sigmalabconsulting.com to uncover high-impact improvement opportunities. 🚀

    For more insights and to assess your organization's excellence, check out our tailored scorecards:

    1. Integrated Research & Business Operations Scorecard

    • Evaluate your R&D and business operations and uncover opportunities for improvement. Integrated Research & Business Operations Scorecard

    2. Data-Driven Portfolio Strategy & Execution Scorecard

    • Evaluate your portfolio, strategy, and execution to uncover opportunities for improvement. Data-Driven Portfolio Strategy & Execution Scorecard

    3. Asset Onboarding Scorecard

    • Evaluate your asset onboarding and management readiness to uncover opportunities for improvement. Asset Onboarding Scorecard

    4. Maintenance Efficiency Scorecard

    • Evaluate your maintenance strategy to unlock operational excellence. Maintenance Efficiency Scorecard

    Find all our links here! https://linktr.ee/sigmalabconsulting

    Want our thoughts on a specific topic? Looking to sponsor this podcast to continue to generate content?Or maybe you have an idea and want to be on our show. Fill out our ...

    Show more Show less
    51 mins
  • 0203: Build or Buy? Developing Internal Process Capabilities vs. Relying on External Experts with Liam O'Neill
    May 28 2025

    Send us a text

    Have you ever noticed the gap between where your organization is and where it needs to be widening every day—especially when workflows are undefined or changing?

    In this episode of Lean by Design, we sit down with Liam O’Neill of BPM‑D to tackle the big question: do you invest in building process capabilities internally or lean on outside consultants? We’ll walk you through evaluating your readiness, embedding process ownership in leadership, and starting with a real business challenge so you can create sustainable, scalable process excellence rather than just putting out fires.

    Learn more about BPMD at https://bpm-d.com/

    Connect with Liam at https://www.linkedin.com/in/l-oneill/

    Ready to assess your organization’s efficiency? Connect with us at leanbydesign@sigmalabconsulting.com to uncover high-impact improvement opportunities. 🚀

    For more insights and to assess your organization's excellence, check out our tailored scorecards:

    1. Integrated Research & Business Operations Scorecard

    • Evaluate your R&D and business operations and uncover opportunities for improvement. Integrated Research & Business Operations Scorecard

    2. Data-Driven Portfolio Strategy & Execution Scorecard

    • Evaluate your portfolio, strategy, and execution to uncover opportunities for improvement. Data-Driven Portfolio Strategy & Execution Scorecard

    3. Asset Onboarding Scorecard

    • Evaluate your asset onboarding and management readiness to uncover opportunities for improvement. Asset Onboarding Scorecard

    4. Maintenance Efficiency Scorecard

    • Evaluate your maintenance strategy to unlock operational excellence. Maintenance Efficiency Scorecard

    Find all our links here! https://linktr.ee/sigmalabconsulting

    Want our thoughts on a specific topic? Looking to sponsor this podcast to continue to generate content?Or maybe you have an idea and want to be on our show. Fill out our ...

    Show more Show less
    45 mins
  • 0202. When Everyone’s Rowing, But the Boat Isn’t Moving
    May 14 2025

    Send us a text

    Have you ever watched a rowing team give it their all only to spin in circles? That’s exactly how we feel when our teams pour in effort without clear roles and responsibilities.

    In this episode of Lean by Design, we explore how vague decision‐making and overlapping tasks quietly drain momentum, leading to missed deadlines and frustrated teams. We’ll share how defining ownership, fostering psychological safety, and using simple digital tools can align everyone’s efforts so your boat actually moves forward.

    Join us to learn how clarity of roles can transform your team’s productivity and make the journey more rewarding for everyone.

    Ready to assess your organization’s efficiency? Connect with us at leanbydesign@sigmalabconsulting.com to uncover high-impact improvement opportunities. 🚀

    For more insights and to assess your organization's excellence, check out our tailored scorecards:

    1. Integrated Research & Business Operations Scorecard

    • Evaluate your R&D and business operations and uncover opportunities for improvement. Integrated Research & Business Operations Scorecard

    2. Data-Driven Portfolio Strategy & Execution Scorecard

    • Evaluate your portfolio, strategy, and execution to uncover opportunities for improvement. Data-Driven Portfolio Strategy & Execution Scorecard

    3. Asset Onboarding Scorecard

    • Evaluate your asset onboarding and management readiness to uncover opportunities for improvement. Asset Onboarding Scorecard

    4. Maintenance Efficiency Scorecard

    • Evaluate your maintenance strategy to unlock operational excellence. Maintenance Efficiency Scorecard

    Find all our links here! https://linktr.ee/sigmalabconsulting

    Want our thoughts on a specific topic? Looking to sponsor this podcast to continue to generate content?Or maybe you have an idea and want to be on our show. Fill out our ...

    Show more Show less
    53 mins
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