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Longevity Roadmap

Longevity Roadmap

By: Buck Joffrey
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 Dr. Buck Joffrey sits down with leading scientists in the field of longevity to explore cutting-edge research, emerging therapies, and what it really takes to live longer—healthier. Alternative & Complementary Medicine Hygiene & Healthy Living
Episodes
  • 142: The Gut-Muscle Axis with Dr. Michael Lustgarten

    142: The Gut-Muscle Axis with Dr. Michael Lustgarten
    Jun 30 2025
    In this episode, Dr. Michael Lustgarten discusses his research on the gut microbiome, serum metabolome, and muscle health in older adults. He shares insights from his journey into the world of aging, the importance of data in health optimization, and the emerging concept of the gut-muscle axis. Dr. Lustgarten emphasizes the significance of metabolites in predicting longevity and the need for personalized health tracking. He also addresses the balance of exercise and the role of fecal microbiota transplantation in health. Learn more about Dr. Michael Lustgarten: https://nutrition.tufts.edu/academics/faculty/michael-lustgarten

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    Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0

    Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/
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    30 mins
  • 141: A Thermostat for Your Body Fat

    141: A Thermostat for Your Body Fat
    Jun 23 2025
    In this conversation, Dr. Stephan J. Guyenet joins Dr. Buck Joffrey to discuss the complex mechanisms of body fat regulation, focusing on the role of the lipostat and leptin. He explains how the body regulates fatness through hormonal signals and the implications of leptin resistance in obesity. The discussion also covers practical strategies for weight management, the impact of stress and sleep on leptin levels, and critiques of the carbohydrate insulin model of obesity. Learn more about Dr. Stephan J. Guyenet: https://www.stephanguyenet.com/

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    Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0

    Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/
    Show more Show less
    29 mins
  • 140: Inside the Inflammatory Clock - Measuring and Reversing Biological Age with Dr. David Furman

    140: Inside the Inflammatory Clock - Measuring and Reversing Biological Age with Dr. David Furman
    Jun 16 2025

    Dr. David Furman and Dr. Buck Joffrey discuss the complexities of immune aging, the role of inflammation in age-related diseases, and how artificial intelligence is being utilized to enhance research in this field. He introduces the concept of the inflammatory age clock, which measures biological aging through immune system signals, and explores potential therapeutic interventions, including nutraceuticals and therapeutic plasma exchange. The discussion also touches on the future of aging research, emphasizing personalized approaches and the democratization of diagnostics.

    Learn more about Dr. David Furman:

    https://www.buckinstitute.org/lab/furman-lab/
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    30 mins
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