Drs Robert Kushner and obesity pharmacotherapy expert Ania Jastreboff discuss how to use the new obesity medications effectively in clinic. Tune in to hear expert recommendations on patient communication, side effects, and more.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982636). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Obesity Treatment & Management https://emedicine.medscape.com/article/123702-treatment

Drugs for Treating Obesity https://pubmed.ncbi.nlm.nih.gov/34783910/

Control-Theory Models of Body-weight Regulation and Body-weight-regulatory Appetite https://pubmed.ncbi.nlm.nih.gov/31494154/

Obesogenic Environments: Current Evidence of the Built and Food Environments https://pubmed.ncbi.nlm.nih.gov/28449616/

FDA-approved Pharmacotherapy for Weight Loss Over the Last Decade https://pubmed.ncbi.nlm.nih.gov/36277516/

Tirzepatide https://pubmed.ncbi.nlm.nih.gov/36251836/

New Frontiers in Obesity Treatment: GLP-1 and Nascent Nutrient-Stimulated Hormone-Based Therapeutics https://pubmed.ncbi.nlm.nih.gov/36706749/

Once-Weekly Semaglutide in Adults With Overweight or Obesity https://pubmed.ncbi.nlm.nih.gov/34192447/

Tirzepatide Once Weekly for the Treatment of Obesity https://pubmed.ncbi.nlm.nih.gov/35658024/

Bariatric Surgery https://emedicine.medscape.com/article/197081-overview

FDA Approves New Drug Treatment for Chronic Weight Management, First Since 2014 https://www.fda.gov/news-events/press-announcements/fda-approves-new-drug-treatment-chronic-weight-management-first-2014

Body Mass Index https://medlineplus.gov/ency/article/007196.htm

Descriptive Analysis of Reported Adverse Events Associated With Anti-obesity Medications Using FDA Adverse Event Reporting System (FAERS) Databases 2013-2020 https://pubmed.ncbi.nlm.nih.gov/34564826/

Antiobesity Drug Therapy: An Individualized and Comprehensive Approach https://pubmed.ncbi.nlm.nih.gov/34341028/

Barriers and Solutions for Prescribing Obesity Pharmacotherapy https://pubmed.ncbi.nlm.nih.gov/32418592/

Addressing Insurance-related Barriers to Novel Antiobesity Medications: Lessons to Be Learned From Bariatric Surgery https://pubmed.ncbi.nlm.nih.gov/36190393/

Certifying Physicians in the Treatment of Obesity https://www.abom.org/

Diabetes and obesity are on the rise, and there are new tools to help the prevention and management of this twin epidemic of "diabesity" in primary care. Drs Robert Kushner and Tim Garvey discuss.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982635). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Obesity Treatment & Management https://emedicine.medscape.com/article/123702-treatment

Type 2 Diabetes Mellitus https://emedicine.medscape.com/article/117853-overview

Diabesity https://diabetesjournals.org/clinical/article/40/4/392/147743/Diabesity

National Diabetes Statistics Report: Estimates of Diabetes and Its Burden in the United States https://www.cdc.gov/diabetes/data/statistics-report/index.html

Prevalence of Diabetes by Race and Ethnicity in the United States, 2011-2016 https://pubmed.ncbi.nlm.nih.gov/31860047/

Trends in Prevalence of Type 1 and Type 2 Diabetes in Children and Adolescents in the US, 2001-2017 https://pubmed.ncbi.nlm.nih.gov/34427600/

CDC Diabetes and Obesity Maps https://www.cdc.gov/diabetes/data/center/slides.html

Diabetes Technology: Standards of Care in Diabetes – 2023 https://pubmed.ncbi.nlm.nih.gov/36507635/

American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan – 2022 Update https://pubmed.ncbi.nlm.nih.gov/35963508/

Mediterranean Diet and Obesity-Related Disorders: What Is the Evidence? https://pubmed.ncbi.nlm.nih.gov/36178601/

The Look AHEAD Study: A Description of the Lifestyle Intervention and the Evidence Supporting It https://pubmed.ncbi.nlm.nih.gov/16855180/

Durability of a Primary Care–Led Weight-Management Intervention for Remission of Type 2 Diabetes: 2-Year Results of the DiRECT Open-Label, Cluster-Randomised Trial https://pubmed.ncbi.nlm.nih.gov/30852132/

Semaglutide https://reference.medscape.com/drug/ozempic-rybelsus-wegovy-semaglutide-1000174

Liraglutide https://reference.medscape.com/drug/victoza-saxenda-liraglutide-999449

Tirzepatide Once Weekly for the Treatment of Obesity https://pubmed.ncbi.nlm.nih.gov/35658024/

Glucagon-Like Peptide 1 Receptor Agonists https://www.ncbi.nlm.nih.gov/books/NBK551568/

Dulaglutide Injection https://medlineplus.gov/druginfo/meds/a614047.html

Sodium-Glucose Transport Protein 2 (SGLT2) Inhibitors https://www.ncbi.nlm.nih.gov/books/NBK576405/

Incretin Hormones: Their Role in Health and Disease https://pubmed.ncbi.nlm.nih.gov/29364588/

Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor Antagonists as Anti-Diabetic Agents https://pubmed.ncbi.nlm.nih.gov/29412817/

How do you medically evaluate a person who presents with obesity? Drs Robert Kushner and Amanda Velazquez share practical tools and pearls for community clinicians.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982633). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Obesity Treatment & Management https://emedicine.medscape.com/article/123702-treatment

A Primer on Smoking Cessation in Primary Care https://www.medscape.com/viewarticle/864524_3

Reasons for Underutilization of Bariatric Surgery: The Role of Insurance Benefit Design https://pubmed.ncbi.nlm.nih.gov/30425002/

Antiobesity Drug Therapy: An Individualized and Comprehensive Approach https://pubmed.ncbi.nlm.nih.gov/34341028/

Taking a Weight History – Using Mnemonics to Learn a Missing Skill in Medical Education [Version 1] https://mededpublish.org/articles/6-215

The Broadening Domain of the Metabolic Syndrome https://www.medscape.org/viewarticle/508282

Mallampati Classification https://emedicine.medscape.com/article/2172419-overview

Acanthosis Nigricans https://emedicine.medscape.com/article/1102488-overview

Cushing's Syndrome https://www.niddk.nih.gov/health-information/endocrine-diseases/cushings-syndrome

Clinical Use of the Edmonton Obesity Staging System for the Assessment of Weight Management Outcomes in People With Class 3 Obesity https://pubmed.ncbi.nlm.nih.gov/35267942/

The Progression of Cardiometabolic Disease: Validation of a New Cardiometabolic Disease Staging System Applicable to Obesity https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866217/

Modern Epigenetics Methods in Biological Research https://pubmed.ncbi.nlm.nih.gov/32645449/