Episodes

  • Reid riffs on Silicon Valley, politics, and the election
    Sep 25 2024
    With Election Day fast approaching, Reid tackles some big questions: Is Silicon Valley leaning increasingly red? How can—and should—the government modernize voting? Is there a place for AI agents in politics? And which party is really best for business right now? For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
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    16 mins
  • Sarah Longwell on politics, AI, and elections
    Sep 18 2024
    What’s driving some of the greatest political divisions and threats to democracy ahead of the 2024 U.S. presidential election? This week, Reid and Aria attempt to unpack this with someone who specializes in listening to American voters and translating those insights, at scale: Republican political strategist and The Bulwark co-founder/publisher Sarah Longwell. Sarah, who also hosts The Focus Group Podcast, joins the show to talk about her experience listening to everyday voters through focus groups — and her perspective on how doing so can help people better understand one another, combat misinformation, and heal some of the deepest divides in America today. She shares her perspective on Donald Trump, the upcoming election, the state of politics in Silicon Valley, AI, the future of the Republican Party, and the value of compromising. Plus, Reid tests GPT-4o’s ability to separate fact from fiction. Note: This conversation is not intended to proselytize or convert anyone. Rather, it is an attempt to learn from someone who has spent hundreds of hours talking to thousands of voters about their lives and politics. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Topics: 03:41 - Hellos and intros 04:55 - The state of politics now 06:08 - Inside the mind of an undecided voter 08:22 - What polls actually tell us 10:04 - What’s different about the political attitude right now 12:22 - How focus groups work, and what they tell us 18:08 - The benefits of qualitative research 18:52 - How can technology improve focus group research? 23:12 - How to become a better listener and persuader 28:21 - The impact and use cases of AI running focus groups 34:03 - When a human touch is necessary 36:37 - AI video-based sentiment analysis 41:05 - Sarah navigating being a lone wolf in politics 45:19 - What Sarah learned fighting for marriage equality 47:25 - How does misinformation spread and stick? 54:08 - What’s next for the Republican party? 57:42 - GPT-4o “spot the fake headline” test 01:02:57 - Rapid-fire questions Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Whether it's Inflection’s Pi, OpenAI’s ChatGPT or other AI tools, each episode will use AI to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
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    1 hr and 12 mins
  • Reid riffs on his personal history with AI
    Sep 11 2024
    Reid reflects on his early exposure to AI as an undergraduate at Stanford and on navigating the space between academia and industry. Plus, he and Aria discuss human outcomes of technology—and how human-centered technologists such as Fei-Fei Li, Mustafa Suleyman, and Kevin Scott have helped him keep those outcomes top of mind. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
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    11 mins
  • Daphne Koller on drug discovery and AI
    Sep 4 2024
    How can scientists leverage AI and machine learning to more effectively research, develop, and deliver new drugs? This week, Reid and Aria talk drug development with renowned computer scientist and executive Dr. Daphne Koller, whose company, insitro, uses machine learning to improve the quality and speed of drug discovery. She addresses several ways AI and ML are already being used to redefine diseases and create better therapeutic interventions. Plus, she shares her experience transitioning from academia to industry. Read the transcript of this episode here: https://www.possible.fm/podcasts/dkoller For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Topics: 00:01: Cold open 00:43: Hellos and intros 3:20: Early involvement in AI 5:00: Overview of drug discovery and its evolution over the last five years 7:50: AI and machine learning impact on biology and drug development 9:09: Pi aside defining AlphaFold 11:37: Areas of acceleration and opportunity in AI and drug discovery 17:21: Synthetic data 21:21: AI implications on therapeutic hypotheses 23:54: Personalized vs. precision medicine 27:04: Closing the data feedback loop 30:31: Exciting announcements 34:24: Privacy and data 36:41: GPT-4 story 38:48: Stuart Russell’s comments on the applications of Koller’s thesis 43:36: AI as a moving target 47:24: How can academia and industry positively impact society and humanity 51:58: insitro’s culture 54:18: - Rapid-fire questions Select mentions: Not the End of the World: How We Can Be the First Generation to build a Sustainable Planet by Hannah Ritchie Stuart Russell Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Whether it's Inflection’s Pi, OpenAI’s ChatGPT or other AI tools, each episode will use AI to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
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    1 hr
  • Reid riffs on the future of human connectivity
    Aug 28 2024
    This week, Reid veers toward science fiction, tackling big questions including: Is a single mentally-linked network in our future? Can and should humans create other sentient beings? Select mentions: David Brin
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    9 mins
  • Nick Thompson on our AI future
    Aug 21 2024
    What might it look like if we used AI to make democracy work better and to make society more equal? In this special live recording of Possible, Aria turns the tables on her co-host, interviewing Reid alongside Atlantic CEO Nick Thompson. They discuss AI-native generations, the future of friendship and social connections, media, data, privacy, and democracy in the age of AI. To kick off the episode, Reid’s avatar makes a cameo. Read the transcript of this episode here: https://www.possible.fm/podcasts/nthompson For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Topics: 1:53 - Hellos and intros 2:15 - A question from Reid’s AI Avatar 6:24 - Defining this moment in technology 10:08 - AI, journalism, and democracy 13:32 - AI and empathy 20:17 - Why AI is exciting for young people 22:44 - How impacts the world of friendship 33:07 - AI and privacy 41:21 - Looking ahead 47:51 - Rapid-fire questions Select mentions: The Worlds I See by Fei-fei Li Earth Species Project Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Whether it's Inflection’s Pi, OpenAI’s ChatGPT or other AI tools, each episode will use AI to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
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    54 mins
  • Reid riffs on AI regulation
    Aug 14 2024
    This week, Aria asks Reid about government regulation of AI, including where the U.S. fits in on the global stage and how America can learn from where the early regulation of social media fell short. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
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    13 mins
  • Gina Raimondo on AI, government, and commerce
    Aug 7 2024
    How can the U.S. government support the use of AI to stimulate innovation, bring healthcare to people more effectively, and educate people more equitably—all while thoughtfully navigating technology’s impact on people’s way of life? On this week’s episode, Reid and Aria sit down with U.S. Secretary of Commerce Gina Raimondo to discuss her work leading the government’s efforts to minimize the risks and maximize the benefits of AI for Americans. She gets into the federal government’s approach to AI innovation and safety, emphasizing the importance of global partnerships. Plus, she shares how the U.S. can make hardware “sexy” again—and why it matters. Read the transcript of this episode here: https://www.possible.fm/podcasts/raimondo For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Topics: 3:30 - Hellos and intros 6:44 - Hopes and goals for American citizens 9:34 - America’s approach to AI compared to its approach to other digital innovations 14:15 - How the U.S. can “make building hardware sexy again” 18:21 - International cooperation on AI 21:39 - How technology leaders can contribute to private-public partnerships 24:14 - What excites Secretary Raimondo most right now 26:35 - How industry can relieve anxiety about job security in an AI-world Select mentions: AI Safety Institute CHIPS Act Regional Technology and Innovation Hubs (Tech Hubs) Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Whether it's Inflection’s Pi, OpenAI’s ChatGPT or other AI tools, each episode will use AI to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
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    34 mins