Episodes

  • Reid riffs on Signal, AI for cancer detection, and GPT-4o image generation
    Apr 2 2025
    In the wake of Atlantic editor-in-chief Jeffrey Goldberg’s accidental inclusion in senior government officials’ Signal group chat discussing war plans, Reid weighs in on how the U.S. government should—and shouldn’t—use encrypted messaging apps. He and Aria also discuss AI-powered breakthroughs in cancer detection and medical diagnostics, along with NVIDIA’s newly announced Superchip and OpenAI’s latest image generation capabilities. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
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    15 mins
  • Andrew Bosworth on AI, wearables, and mixed reality
    Mar 26 2025
    The evolution of AI is changing the way we interact with the physical world, not just in how we use this technology, but also where and how we access it. In this episode, Reid and Aria sit down with Meta’s Chief Technology Officer, Andrew “Boz” Bosworth, who is pioneering wearables for the company. Boz’s journey in the tech sector has taken him from working on Microsoft Visio to founding Reality Labs, Meta’s AR and VR division. Now, he’s focused on the next frontier in mixed realities with his latest project, Orion, a pair of AR glasses. Boz offers an Orion demo and shares his vision for wearables as an equalizing technology that can unlock superpowers for every person. Plus, they check-in on the state of AI as it relates to open source software, safety, hyperscalers, and startups. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Topics: 1:03 - Episode introduction 3:36 - How Boz’s farm upbringing influenced his career and perspective on the digital world 7:02 - How will wearables influence how we navigate the physical and digital worlds? 9:46 - Meta's AI philosophy 11:27 - Pi explains Norbert Wiener's construct of information theory 14:28 - What would it take to build AI world models? 15:09 - What are the most significant use cases for Orion? 19:01 - Can Orion accommodate monocular vision? 20:00 - Boz's response to Orion skeptics 22:29 - Boz gives predictions on our AI future 25:09 - What would it look like to have a compatible system of wearables? 27:30 - Unexpected discoveries from Orion testing 29:33 - What is Meta's focus in the AI space for the years to come? 30:48 - How do we ensure that AI innovation is used for good? 35:28 - Boz responds to Meta's changes in fact checking policy 37:11 - How will hyperscalers and start-ups flourish in the AI game? 40:06 - Boz shares his review on “The Wild Robot” 42:24 - Rapid-fire questions Select mentions: The Martian by Andy Weir Project Hail Mary by Andy Weir I Am a Strange Loop by Douglas Hofstadter J. C. R. Licklider, psychologist and computer scientist Douglas Engelbart, engineer and computer science pioneer Norbert Wiener, computer scientist and mathematician Yann LeCun, computer scientist and Chief AI Scientist at Meta Michael Abrash, Chief Scientist, Reality Labs, Meta Garry Kasparov, Russian chess grandmaster 4-H, a youth development program from the USDA The Biometric Information Privacy Act (BIPA) Qualified Business Income Deduction (QBI) Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Whether it's Inflection’s Pi, OpenAI’s ChatGPT or other AI tools, each episode will use AI to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
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    50 mins
  • Re-release of Trevor Noah | Celebrating two years of Possible!
    Mar 21 2025
    It's been two years since the Possible podcast began, so we’re taking a moment to return to the beginning: our series launch episode with Trevor Noah. First, Aria and Reid sit down to revisit aspects of the original conversation, exploring just how much has changed in the AI space since Possible launched. Then, you’ll hear the Webby-award-winning episode in full. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
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    1 hr and 17 mins
  • Reid riffs on AI as “American Intelligence” and a prediction from Anthropic’s CEO
    Mar 19 2025
    Is code going to be 100% AI-generated a year from now? Reid shares where he diverges from Anthropic CEO Dario Amodei's recent prediction about the future of programming. Plus, he and Aria discuss “vibe revenue,” along with how America can maintain soft power through software. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
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    17 mins
  • Dana Griffin on AI, belonging, and intergenerational connection
    Mar 12 2025
    Loneliness is a public health crisis affecting people of all ages.This week on Possible, Reid and Aria sit down with someone using AI to bridge generational gaps and combat the loneliness epidemic. Dana Griffin is co-founder and CEO of Eldera, a global platform using AI to foster intergenerational connections. Raised by her grandparents and mentored by older adults throughout her life, Dana is on a mission to help people see aging as an asset. Dana shares how Eldera uses AI to safely and meaningfully connect kids with older mentors, addressing loneliness, declining mental health, and lost wisdom. They explore how technology can support human connection—rather than replace it—along with what an "age-integrated society” could unlock. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Topics: 1:20 - Episode introduction 3:37 - Dana’s early life and how it shaped her perspective on intergenerational bonds 6:09 - How ageism creates a waste of human potential 9:01 - Policy and tech solutions can help reintegrate older adults 12:11 - Social media worsens isolation, but AI can help foster real connection 14:31 - Eldera’s mission of bridging generations through AI-powered mentorship 18:52 - Opposite backgrounds create stronger bonds when matching mentors and mentees 22:44 - Intergenerational mentorship as a form of healthcare 26:34 - Using AI to map and amplify generational knowledge 30:26 - Midroll ad break 30:35 - AI enhances, but never replaces, human connection 34:05 - Encouraging confidence among older adults through Eldera’s wisdom portrait 37:26 - Scaling Eldera and working towards a society where we value the impact of elders 41:17 - The barriers and opportunities of scaling Eldera 44:34 - How cultural perspectives and global views on aging shape intergenerational ties 48:33 - Rapid fire Select mentions: Fei-Fei Li on spatial intelligence and human-centered AI Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. Each episode seeks to advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
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    57 mins
  • Reid riffs on AI wearables, quantum, and Deep Research
    Mar 5 2025
    Reid reacts to the news of HP acquiring Humane Ai Pin and weighs in on the future of wearable tech, quantum, and copyright law. Plus, AI whiz Parth Patil (formerly Clubhouse’s first data scientist) joins the show to discuss why he’s excited about OpenAI’s Deep Research tool, “vibe coding,” and coding copilots. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
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    27 mins
  • Latanya Sweeney on AI, trust, and privacy
    Feb 26 2025
    How does the rise of AI impact our sense of what’s true? How can humans maintain a degree of individual privacy and unlock the benefits of AI while mitigating potential harms? In this episode, Reid and Aria sit down with data privacy pioneer Latanya Sweeney, Professor of Government and Technology at Harvard; former Chief Technology Officer at the U.S. Federal Trade Commission; and founder of Harvard’s Public Interest Tech Lab and Data Privacy Lab. They discuss the future of privacy protection, technocracy vs. democracy, teaching in the age of AI, governance, content moderation, and more. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Topics: 0:55 - Episode introduction 3:05 - Lessons from Latanya's grandparents 4:30 - Latanya's early days at MIT 5:38 - Re-identification and Governor William Weld example 10:50 - Historical arc of AI 12:24 - The Third Industrial Revolution 15:11 - Technocracy vs. democracy 18:38 - Making technological literacy a federal priority 21:03 - Divisiveness in AI 26:20 - Exploring humanity's "cultural dream" of AI 27:17 - Midroll ad break 27:49 - What will it take to build trust in AI at scale? 31:11 - Inflection's Pi lists key elements for a tech-conscious social contract 32:04 - Latanya responds to Pi and talks LLM truth-telling 34:20 - The best of public interest technology 37:02 - Improving content moderation 43:24 - Democratizing public interest technology 44:24 - Feedback and improvements for LinkedIn 47:53 - What does AI mean for education? 49:35 - Insights from Latanya's Harvard students 51:08 - Rapid-fire questions Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Whether it's Inflection’s Pi, OpenAI’s ChatGPT or other AI tools, each episode will use AI to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
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    57 mins
  • Reid riffs on the AI race with China and if the US should regulate AI
    Feb 19 2025
    Following last week’s chat with former diplomat and author Anja Manuel, Reid talks about the potential benefits of an FDA for AI, the current status of the global race for artificial intelligence, and predicting what’s to come from American AI companies. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
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    13 mins