In this episode, host Dr Michael Saag speaks with Dr Paul Volberding, founder of the world's first dedicated HIV outpatient clinic, about their clinical experience treating HIV from the early days of the pandemic until now. They discuss the medical breakthroughs that they have seen over the years and how the history of HIV treatment directly informs treatment today.

Relevant disclosures can be found with the episode show notes on Medscape.com (https://www.medscape.com/viewarticle/963236). The topics and discussions are planned, produced, and reviewed independently of our advertiser. This podcast is intended only for US healthcare professionals.

Resources

Kaposi sarcoma clinical presentation https://emedicine.medscape.com/article/279734-clinical

Lymphadenopathy: endpoint or prodrome? Update of a 24-month prospective study https://pubmed.ncbi.nlm.nih.gov/6335951/

Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS) https://pubmed.ncbi.nlm.nih.gov/6189183/

The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial https://pubmed.ncbi.nlm.nih.gov/3299089/

The history of PCR http://siarchives.si.edu/research/videohistory_catalog9577.html

History of HAART -- the true story of how effective multi-drug therapy was developed for treatment of HIV disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1716971/