Drs Sumanta Pal and David A. Braun discuss the role of single-cell sequencing as a biomarker in renal cell carcinoma, how it is evolving, and how it might apply in other domains.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/984238). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Single-Cell RNA Sequencing Technologies and Applications: A Brief Overview https://pubmed.ncbi.nlm.nih.gov/35352511/

Progressive Immune Dysfunction With Advancing Disease Stage in Renal Cell Carcinoma https://pubmed.ncbi.nlm.nih.gov/33711273/

Immune Checkpoint Inhibitors in Non-Conventional Histologies of Renal-Cell Carcinoma https://pubmed.ncbi.nlm.nih.gov/36758960/

Prevalence and Landscape of Actionable Genomic Alterations in Renal Cell Carcinoma https://pubmed.ncbi.nlm.nih.gov/34261695/

Molecular Profiling in Early ER+ Breast Cancer to Aid Systemic Therapy Decisions https://pubmed.ncbi.nlm.nih.gov/36862337/

Dysbiosis of a Microbiota-Immune Metasystem in Critical Illness Is Associated With Nosocomial Infections https://pubmed.ncbi.nlm.nih.gov/36894652/

A Single-Cell Atlas Reveals Shared and Distinct Immune Responses and Metabolic Profiles in SARS-CoV-2 and HIV-1 Infections https://pubmed.ncbi.nlm.nih.gov/36992700/

Revealing the Vectors of Cellular Identity With Single-Cell Genomics https://pubmed.ncbi.nlm.nih.gov/27824854/

Nivolumab Versus Everolimus in Patients With Advanced Renal Cell Carcinoma: Updated Results With Long-term Follow-up of the Randomized, Open-Label, Phase 3 CheckMate 025 Trial https://pubmed.ncbi.nlm.nih.gov/32673417/