
Sickle cell anemia
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About this listen
Sickle cell anemia is a genetic disorder caused by a mutation in the hemoglobin gene (HBB), resulting in the production of abnormal hemoglobin (HbS). The sickled red blood cells are less effective at transporting oxygen, break down prematurely (causing anemia), and can block blood vessels, leading to pain and organ damage.
In this Episode Dr. Auma takes us throgh the Pathophysiology and the Management like:
Pain relief during crises (NSAIDs, opioids)
Hydroxyurea to reduce crises
Blood transfusions to manage anemia
Vaccinations and antibiotics to prevent infections
Hydration and oxygen therapy during crises
Overall, treatment focuses on alleviating symptoms, preventing complications, and improving quality of life.
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