
The Antioxidant of Antioxidants: Lipoic Acid
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About this listen
In this episode of Daily Value, we look at the often overlooked yet potent nutrient, alpha lipoic acid, which is integral to mitochondrial energy metabolism and cellular health. Discovered in 1937, ALA acts as a primary antioxidant in the body. This episode covers the distinction(s) between supplemental and endogenous ALA. The latter is able to cross the blood-brain barrier and is used therapeutically for conditions like diabetic neuropathy, oxidative stress, and metal detoxification. I will also explain the importance of selecting the right form of ALA , recommended dosages for different formulations and their potential benefits in metabolic health.
00:00 Introduction to Alpha Lipoic Acid
00:53 Discovery and Biological Role
02:05 Antioxidant Properties and Functions
03:28 Supplemental Benefits and Research
06:28 Forms and Bioavailability
09:52 Therapeutic Threshold and Dosing
11:27 Safety and Efficacy
13:14 Conclusion and Recommendations
PMID: 39456481
PMID: 18069903
PMID: 29191830
PMID: 25971966
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