This Week in Virology

By: Vincent Racaniello
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  • Summary

  • TWiV is a podcast about viruses - the kind that make you sick.
    Vincent Racaniello 2022
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Biological Sciences Natural History
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Episodes
  • TWiV 1167: Virus cloak and entry

    TWiV 1167: Virus cloak and entry
    Nov 17 2024

    TWiV reveals a novel H5N1 reassortant virus in Cambodia, circulating vaccine derived poliovirus type 2 in more countries, circulation in the blood of humans of infectious parvovirus B19 coated with active proteases, and B cell receptor dependent enhancement of dengue virus infection.

    Hosts: Vincent Racaniello, Dickson Despommier, Kathy Spindler, and Brianne Barker

    Subscribe (free): Apple Podcasts, RSS, email

    Become a patron of TWiV!

    Links for this episode
    • MicrobeTV Discord Server
    • MicrobeTV Fundraiser
    • Novel H5N1 in Cambodia (medRxiv)
    • More cVDVP2 circulation (polioeradication.org)
    • Infectious parvovirus B19 with proteases (Nat Comm)
    • B cell receptor enhancement of dengue disease (PLoS Path)
    • Timestamps by Jolene. Thanks!
    Weekly Picks

    Brianne – See How Many Lives Vaccines Have Saved Around the World based on Lancet study
    Dickson – 2024 Wildlife Photographer of the Year
    Kathy – 450 Million year old arthropods preserved in fool’s gold. Primary article Pyrite video
    Vincent – ‘We need to be ready for a new world’: scientists globally react to Trump election win

    Listener Picks

    Jack – Coronavirus vaccine update

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    Content in this podcast should not be construed as medical advice.
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    1 hr and 43 mins
  • TWiV 1166: Clinical update with Dr. Daniel Griffin

    TWiV 1166: Clinical update with Dr. Daniel Griffin
    Nov 16 2024
    In his weekly clinical update, Dr. Griffin apprises us about the first case of highly pathogenic influenza in Canda, children dying of influenza infection and novel genetic reassortments of the virus, the Marburg virus outbreak in Rwanda, number of mpox infections, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, how scientific mistrust has affected COVID-19 vaccine administration, resolution of the FDA hold on Novovax’s combination influenza and COVID vaccine, where to find PEMGARDA, how Paxlovid SAVES you money, when to use steroids to treat COVID-19 and how trace amounts of cytokines elicted during SARS-CoV-2 infection negatively impact cardiac function. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Bird flu flew into British Columbia Canada (Global News Canada)H5N1 in British Columbia (CIDRAP) Highly Pathogenic Avian Influenza flies commercial and domestic (USDA)Countdown till the end of Marburg outbreak (WHO Rwanda) First kid’s death due to flu (CIDRAP)Influenza weekly surveillance report: clift notes (CDC FluView)H5N1 novel reassortments in migratory birds in China (Emerging Infectious Diseases)Serologic evidence of recent infection with highly pathogenic avian influenza A (MMWR)Seriously? 50,000 mpox cases in African outbreak (CIDRAP)Respiratory virus activity (CDC Respiratory Illnesses)COVID-19 deaths (CDC)COVID-19 national and regional trends (CDC)Waste water scan for 11 pathogens (WastewaterSCan)COVID-19 variant tracker (CDC)SARS-CoV-2 genomes galore (Nextstrain) Science trust: behind COVID 19 vaccine acceptance (Vaccine X) Vaccine mistrust levels are not budging (Healthday)FDA clinical hold lifted on Novavax’s combination COVID-flu vaccine(Reuters)Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)Fusion center near you….if in NY (Prime Fusions) CDC Quarantine guidelines (CDC)NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society)Drug interaction checker (University of Liverpool)Real-world effectiveness of nirmatrelvir-ritonavir and molnupiravir (CMI: Clinical Microbiology and Infection)Alleviation of COVID-19 Symptoms and Reduction in Healthcare Utilization Among High-Risk Patients Treated With Nirmatrelvir/Ritonavir (CID)Molnupiravir safety and efficacy (JMV)Convalescent plasma recommendation for immunocompromised (ID Society)What to do when sick with a respiratory virus (CDC)When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)Managing healthcare staffing shortages (CDC)Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org)Secondary bacterial infection follows COVID-19 (Nature Communications)Daniel Griffin’s evidence based medical practices for long COVID (OFID)Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function (Nature Medicine)Letters read on TWiV 1166Dr. Griffin’s COVID treatment summary (pdf)Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv
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    46 mins
  • TWiV 1165: What doesn't kill us primes our macrophages

    TWiV 1165: What doesn't kill us primes our macrophages
    Nov 10 2024

    TWiV notes the passing of virologist Diane Griffin, first H5N1 influenza virus in US pigs, Innate immune control of influenza virus interspecies adaptation via IFITM3, and antiviral trained innate immunity in alveolar macrophages after SARS-CoV-2 infection reduces secondary influenza A virus disease.

    Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

    Subscribe (free): Apple Podcasts, RSS, email

    Become a patron of TWiV!

    Links for this episode
    • MicrobeTV Discord Server
    • MicrobeTV Fundraiser
    • Diane Griffin passes (Johns Hopkins)
    • Diane Griffin on TWiV 453
    • First H5N1 influenza virus in US pigs (CIDRAP)
    • IFITM3 controls interspecies influenza virus infection (Nat Comm)
    • Trained innate immunity by alveolar macrophages (Immunity)
    • Timestamps by Jolene. Thanks!
    Weekly Picks

    Angela – See a giant ‘ghost particle’ detector and more — October’s best science images
    Brianne – October 27 APoD: Bat nebula
    Dickson – Nikon Small World Contest 2024 winners
    Kathy – AAAS 150th anniversary video, celebrating scientists and Pew’s 2024 annual Trust in Science survey findings
    Rich – Cats Basically Are a Liquid After All, Study Confirms
    Alan – HHMI’s Beautiful Biology site
    Vincent – EcoHealth Alliance Fights Back

    Listener Picks

    Hunter – Don’t stop me now: Queen’s Brian May on saving badgers — and the scientific method
    Anne – Reasons to be cheerful

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    Content in this podcast should not be construed as medical advice.
    Show more Show less
    1 hr and 45 mins

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Profile Image for Kari Helgerud

Love it!

Science first and yet entertaining.
Wonderful gang full of knowledge and joy for related topics.

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Profile Image for M. Rossiter

Excellent Source

I found TWiV through the recommendation of another podcast. Like many I am a post covid follower and I have really appreciated TWiV as a source of current and accurate information. The clinical updates with Dr. Griffin are so useful . Dr Gritting uses language that I, a custodian i.e. not a science professional am able to understand. I find the clinical updates really ease my anxieties because finally I understand what is going on around me. Sometimes the other episodes I struggle to totally follow along but I always finish having learned something I didn't know before listening. Turns out virology and immunology is quite fascinating!

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Profile Image for norman rogers

Fun team

You need a background in Bio to enjoy this podcast, but if you are on the in you should have a great time.

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Very good science podcast!

The content is really good and always interesting with many great guests. Good job guys!

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Profile Image for portia shao

A good thing from the pandemic years

I discovered TWiV during 2020 due to the desire for more accurate and unbiased information about the viruses and then stayed for the good and interesting science. I never liked biology before but have found the discussions to be reasons to get interested in not only virology but biology, microbiology, even medicine. Although I don’t understand all the science, to hear the unfamiliar multiple times made them less intimidating and I feel like I am sitting in the same room as the host and guest scientists week after week when different topics are being discussed. The weekly clinical updates are also keeping me well informed about the viruses that we should be aware of in a timely way. Love this podcast and many sister podcasts from microbe.tv

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