This Week in Virology

By: Vincent Racaniello
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  • Summary

  • TWiV is a podcast about viruses - the kind that make you sick.
    Vincent Racaniello 2022
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Episodes
  • TWiV 1153: Viruses that (can) make you well

    TWiV 1153: Viruses that (can) make you well
    Sep 29 2024

    From the Viruses of Microbes meeting in Cairns, Australia, TWiV speaks with Krystyna and Rob about their research on using bacteriophages to treat bacterial infections.

    Hosts: Vincent Racaniello and Jolene Ramsey

    Guests: Krystyna Dabrowska and Rob Lavigne

    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

    Become a patron of TWiV!

    Links for this episode
    • MicrobeTV Discord Server
    • Viruses of Microbes 2024
    • Immune responses to phages (Front Immunol)
    • Engineering bacteriolytic enzymes (Front Immunol)
    • 100 cases of phage therapy (Nat Micro)
    • Synthetic biology potential of bacteriophages (Nat Micro)
    • Timestamps by Jolene. Thanks!

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    Content in this podcast should not be construed as medical advice.
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    55 mins
  • TWiV 1152: Clinical update with Dr. Daniel Griffin

    TWiV 1152: Clinical update with Dr. Daniel Griffin
    Sep 28 2024
    In his weekly clinical update, Dr. Griffin deep dives into the durability of the antibody response following mpox vaccination, vaccine security, global mpox circulation, the origins of SARS-CoV-2, including a list TWiV episodes and combatting scientific misinformation, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, where to find PEMGARDA, a reminder of how and when to use steroids to treat COVID-19, what do when healthcare workers succumb to SARS-CoV-2 infection, if remdesivir + dexamethasone lowers mortality of hospitalized COVID-19 patients and the finding of how SARS-CoV-2 infection impacts memory and cognition. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Waning vaccine protection against mpox…..isn’t this the way the humoral immune response works? (CIDRAP) 1:46Uncontrollable mpox outbreak in Africa (Reuters) 4:10Antibodies elicited by the Jynneos vaccine against mpox contract after 6-9 months….can you believe? (medrxiv) 4:45Mpox vaccine for adolescents approved (Pharmaceutical Technology) 14:05 Clade 1b mpox visiting India (CIDRAP) 15:05 Mpox clade 1b in Kerala (ANI South Asia’s Leading Multimedia News Agency) 15:13US government orders $63M worth of small pox/mpox vaccine (Reuters) 15:34Mpox donations boosting global supply (US Department of Health and Human Services)1 million mpox vaccine doses for Africa….with love from US government (CIDRAP) 15:55 Speed doses of mpox vaccine (CIDRAP)Mpox vaccine donations (UNICEF) 17:35 Bavarian Nordic mpox vaccine (Yahoo finances)Early epicenter of COVID-19 pandemic Huanan seafood market (Science) 23:07Wildlife trade likely source of SARS-CoV-2 (Science) 23:16Zoonotic origins of SARS-CoV-2 (Science) 23:20Surveillance at the Huanan Seafood market (Europe PMC) 25:03TWiV shout outs…..all for the SARS-CoV-2 spill over from nature 25:31 TWiV 1019: Eddie Holmes on SARS-CoV-2 originsTWiV 1017: From Nature, not a labTWiV 995: Viral origin storiesTWiV 940: Eddie Holmes in on viral originsTWiV 876: Spillover market with Michael WorobeyTWiV 762: SARS-CoV-2 origins with Robert GarryTWiV 760: SARS-CoV-2 origins with Peter Daszak, Thea Kølsen Fischer, Marion KoopmansTWiV 774: Kristian Andersen, Robert Garry, and the deleted SARS-CoV-2 sequences Genetic tracking of market wildlife and viruses at Huanan Market (Cell) 18:56Combatting scientific misinformation (microbeTV: TWiV) 34:14COVID-19 deaths (CDC) 35:20COVID-19 national and regional trends (CDC)Waste water scan for 11 pathogens (WastewaterSCan)COVID-19 variant tracker (CDC)SARS-CoV-2 genomes galore (Nextstrain)Suggestion for the use of a new preventive COVID-19 agent (IDSA) IDSA Guidelines on the Treatment and Management of Patients with COVID-19 (IDSA)Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) CDC Quarantine guidelines (CDC)NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society)Drug interaction checker (University of Liverpool)Molnupiravir outcomes 3 and 6 months after treatment (LANCET Infectious Diseases)Antivirals and post-COVID-19 conditions (LANCET Infectious Disease)Molnupiravir safety and efficacy (JMV)Convalescent plasma recommendation for immunocompromised (ID Society)What to do when sick with a respiratory virus (CDC)When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)Managing healthcare staffing shortages (CDC)Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org)Lower mortality risk associated with remdesivir + dexamethasone versus dexamethasone for hospitalized COVID-19 patients (CID) 39:17Changes in memory and cognition during the SARS-CoV-2 human challenge study (eClinical Medicine) 42:25Letters read on TWiV 1152 48:18Dr. Griffin's COVID treatment summary (pdf)Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv
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    58 mins
  • TWiV 1151: Hotel California for Phage

    TWiV 1151: Hotel California for Phage
    Sep 22 2024

    TWiV reviews polio vaccination campaign in Gaza, viruses with zoonotic potential in farmed fur animals, low HPV vaccination in North Texas associated with high rates of cervical cancer, a large flavivirus genome that does not encode error correction machinery, and antiphage defense through inhibition of virion assembly.

    Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Jolene Ramsey

    Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

    Become a patron of TWiV!

    Links for this episode
    • MicrobeTV Discord Server
    • Polio vaccination in Gaza (Reuters)
    • Zoonotic viruses in farmed fur animals (Nature)
    • HPV vaccination and cancer rates (JAMA Net Open)
    • 40 kb RNA genome without error correction (PNAS)
    • Stopping the phage tape measure protein (Nat Commun)
    • Tail assembly interference (Nat Commun)
    • Letters read on TWiV 1151
    • Timestamps by Jolene. Thanks!
    Weekly Picks

    Dickson – Digital nature pics winners 2024 Wildlife Photographer of the Year
    Alan – Adorable story about a Nigerian paralympian couple who are both polio survivors
    Jolene – Capsid assembly model with self-assembling pentamers in 3D print model (plus three more models now available if search self assembling virus) and Wonderlab article about exhibit using this to teach about viral patterns in Bloomington Indiana Science museum
    Vincent – The collapse of bat populations led to more than a thousand infant deaths

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    Content in this podcast should not be construed as medical advice.
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    1 hr and 44 mins
Biological Sciences Natural History
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Love it!

Science first and yet entertaining.
Wonderful gang full of knowledge and joy for related topics.

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Excellent Source

I found TWiV through the recommendation of another podcast. Like many I am a post covid follower and I have really appreciated TWiV as a source of current and accurate information. The clinical updates with Dr. Griffin are so useful . Dr Gritting uses language that I, a custodian i.e. not a science professional am able to understand. I find the clinical updates really ease my anxieties because finally I understand what is going on around me. Sometimes the other episodes I struggle to totally follow along but I always finish having learned something I didn't know before listening. Turns out virology and immunology is quite fascinating!

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Fun team

You need a background in Bio to enjoy this podcast, but if you are on the in you should have a great time.

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Very good science podcast!

The content is really good and always interesting with many great guests. Good job guys!

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Profile Image for portia shao

A good thing from the pandemic years

I discovered TWiV during 2020 due to the desire for more accurate and unbiased information about the viruses and then stayed for the good and interesting science. I never liked biology before but have found the discussions to be reasons to get interested in not only virology but biology, microbiology, even medicine. Although I don’t understand all the science, to hear the unfamiliar multiple times made them less intimidating and I feel like I am sitting in the same room as the host and guest scientists week after week when different topics are being discussed. The weekly clinical updates are also keeping me well informed about the viruses that we should be aware of in a timely way. Love this podcast and many sister podcasts from microbe.tv

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