Biography of Resistance
The Epic Battle Between People and Pathogens
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Narrated by:
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Kyle Tait
About this listen
Award-winning Boston University educator and researcher Muhammad H. Zaman provides a chilling look at the rise of antibiotic-resistant superbugs, explaining how we got here and what we must do to address this growing global health crisis.
In September 2016, a woman in Nevada became the first known case in the US of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions. “It will be like the great plague of the middle ages, the influenza pandemic of 1918, the AIDS crisis of the 1990s, and the Ebola epidemic of 2014 all combined into a single threat”, Muhammad H. Zaman warns.
The Biography of Resistance is Zaman’s riveting and timely look at why and how microbes are becoming superbugs. It is a story of science and evolution that looks to history, culture, attitudes and our own individual choices and collective human behavior. Following the trail of resistant bacteria from previously uncontacted tribes in the Amazon to the isolated islands in the Arctic, from the urban slums of Karachi to the wilderness of the Australian outback, Zaman examines the myriad factors contributing to this unfolding health crisis - including war, greed, natural disasters, and germophobia - to the culprits driving it: pharmaceutical companies, farmers, industrialists, doctors, governments, and ordinary people, all whose choices are pushing us closer to catastrophe.
Joining the ranks of acclaimed works like Microbe Hunters, The Emperor of All Maladies, and Spillover, A Biography of Resistance is a riveting and chilling tale from a natural storyteller on the front lines, and a clarion call to address the biggest public health threat of our time.
©2020 Muhammad H. Zaman (P)2020 HarperCollins PublishersListeners also enjoyed...
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Dr. Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys' club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried.
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If only most of the public knew these facts
- By David Getoff, CCN on 06-18-20
By: Dr. Judy Mikovits, and others
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Plagues, Pandemics and Viruses
- From the Plague of Athens to COVID-19
- By: Heather E. Quinlan
- Narrated by: Samara Naeymi
- Length: 14 hrs and 28 mins
- Unabridged
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It can come in waves - like tidal waves. It changes societies. It disrupts life. It ends lives. As far back as 3000 B.C.E. (the Bronze Age), plagues have stricken mankind. COVID-19 is just the latest example, but history shows that life continues. It shows that knowledge and social cooperation can save lives. Viruses are neither alive nor dead and are the closest thing we have to zombies. Their only known function is to replicate themselves, which can have devastating consequences on their hosts.
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Somewhat elemental
- By Bertha Watkins on 10-23-21
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Viruses, Plagues, and History
- Past, Present, and Future
- By: Michael B. A. Oldstone
- Narrated by: L.J. Ganser
- Length: 13 hrs and 38 mins
- Unabridged
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The story of viruses and humanity is a story of fear and ignorance, of grief and heartbreak, and of great bravery and sacrifice. Michael Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity, focusing mostly on the most famous viruses. For this revised edition, Oldstone includes discussions of new viruses like SARS, bird flu, virally caused cancers, chronic wasting disease, and West Nile. Viruses, Plagues, and History paints a sweeping portrait of humanity's long-standing conflict with our unseen viral enemies.
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very detailed, but very statistical
- By ekhensel15 on 01-12-19
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The Secret History of the War on Cancer
- By: Devra Davis Ph.D.
- Narrated by: Pam Ward
- Length: 19 hrs and 11 mins
- Unabridged
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The War on Cancer was run by leaders of industries that made cancer-causing products and sometimes also profited from drugs and technologies for finding and treating the disease. Filled with compelling personalities and never-before-revealed information, The Secret History of the War on Cancer shows how we began fighting the wrong war, with the wrong weapons, against the wrong enemies, a legacy that persists to this day.
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Silly Book
- By Adam Smith on 12-24-14
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The HPV Vaccine on Trial
- Seeking Justice for a Generation Betrayed
- By: Mary Holland, Kim Mack Rosenberg, Eileen Iorio
- Narrated by: Caroline Slaughter
- Length: 13 hrs and 41 mins
- Unabridged
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Cancer strikes fear in people’s hearts around globe. So the appearance of a vaccine to prevent cancer - as we are assured the human papillomavirus (HPV) vaccine will - seemed like a game-changer. Since 2006, over 80 countries have approved the vaccine, with glowing endorsements from the world’s foremost medical authorities. Bringing in over $2.5 billion in annual sales, the HPV vaccine is a pharmaceutical juggernaut. Yet scandal now engulfs it worldwide. The HPV Vaccine on Trial is a shocking tale, chronicling the global efforts to sell and compel this alleged miracle.
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Outstanding Investigative Book!
- By Barbara Loeppke on 10-02-19
By: Mary Holland, and others
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The Demon Under The Microscope
- By: Thomas Hager
- Narrated by: Stephen Hoye
- Length: 12 hrs and 14 mins
- Unabridged
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The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic medication. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.
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Great Book!!!!!
- By Amazon Customer on 05-21-08
By: Thomas Hager
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Denialism
- How Irrational Thinking Hinders Scientific Progress, Harms the Planet, and Threatens Our Lives
- By: Michael Specter
- Narrated by: Richard Poe
- Length: 8 hrs and 33 mins
- Unabridged
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New Yorker staff writer Michael Specter has twice won the Global Health Council’s Excellence in Media Award, as well as the Science Journalism Award from the American Association for the Advancement of Science. In Denialism, he fervently argues that people are turning away from new technologies and engaging in a kind of magical thinking that is hindering scientific progress.
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A compelling read
- By S on 05-17-11
By: Michael Specter
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Presidential Takedown
- How Anthony Fauci, the CDC, NIH, and the WHO Conspired to Overthrow President Trump
- By: Dr. Paul Elias Alexander, Kent Heckenlively
- Narrated by: Bob Johnson
- Length: 9 hrs and 40 mins
- Unabridged
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In January 2020, Donald Trump was on the fast track to an easy re-election. While his first two years had been stymied by House Speaker Paul Ryan, Senate Majority Leader Mitch McConnell, and the Democrats, his third year had been one of remarkable success. The United States had low unemployment and was making strides across the globe. The president's rallies were well-attended, and he was being projected to win four hundred electoral votes and about forty-five states. Then came COVID-19.
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Must listen!!
- By Christina Borkowski on 01-10-23
By: Dr. Paul Elias Alexander, and others
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The Great Influenza
- The Epic Story of the Deadliest Plague in History
- By: John M. Barry
- Narrated by: Scott Brick
- Length: 19 hrs and 26 mins
- Unabridged
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In the winter of 1918, at the height of World War I, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in 24 weeks than AIDS has killed in 24 years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision between modern science and epidemic disease.
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Great book but very disturbing...
- By Tim on 01-15-09
By: John M. Barry
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The Pandemic Century
- One Hundred Years of Panic, Hysteria, and Hubris
- By: Mark Honigsbaum
- Narrated by: John Lee
- Length: 13 hrs and 40 mins
- Unabridged
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Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing catastrophic outbreaks of infectious disease. Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 "parrot fever" pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.
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Pretty good
- By Baz 12345 on 04-03-20
By: Mark Honigsbaum
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Happy Accidents
- Serendipity in Major Medical Breakthroughs in the Twentieth Century
- By: Morton A. Meyers
- Narrated by: Richard Waterhouse
- Length: 12 hrs and 37 mins
- Unabridged
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Happy Accidents is a fascinating, entertaining, and highly accessible look at the surprising role serendipity has played in some of the most important medical discoveries in the 20th century. What do penicillin, chemotherapy drugs, X-rays, Valium, the Pap smear, and Viagra have in common? They were each discovered accidentally, stumbled upon in the search for something else. In discussing medical breakthroughs, Dr. Morton Meyers makes a cogent, highly engaging argument for a more creative, rather than purely linear, approach to science. And it may just save our lives!
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Don't waste your money!
- By Amazon Customer on 03-20-16
By: Morton A. Meyers
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Ravenous
- Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection
- By: Sam Apple
- Narrated by: Mark Bramhall
- Length: 12 hrs and 58 mins
- Unabridged
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The Nobel laureate Otto Warburg was widely regarded in his day as one of the most important biochemists of the 20th century, a man whose research was integral to humanity’s understanding of cancer. He was also among the most despised figures in Nazi Germany. As a Jewish homosexual living openly with his male partner, Warburg represented all that the Third Reich abhorred. Yet Hitler and his top advisors dreaded cancer, and protected Warburg in the hope that he could cure it.
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Highly recommended, a must read.
- By Joerg on 06-10-21
By: Sam Apple
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- By: Thomas Hager
- Narrated by: Angelo Di Loreto
- Length: 8 hrs and 39 mins
- Unabridged
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Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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Engrossing to physicians & lay persons alike
- By C. White on 03-08-19
By: Thomas Hager
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Living with Dad was like living with a stranger—as a kid I often had trouble connecting and relating to him. But I was always proud of him. Even before Star Trek, I’d see him popping up in bit roles on some of my favorite TV shows like Get Smart, Sea Hunt, and The Man From U.N.C.L.E. And then one night he brought home Polaroids of himself in makeup and wardrobe for a pilot he was working on. It was December 1964 and nobody had heard of Star Trek. Still, the eight-year-old me had watched enough Outer Limits and My Favorite Martian to understand exactly what I was looking at.
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“What the skeleton is to anatomy, the peasant is to history, its essential hidden support.” For over the past century and a half, and still more rapidly in the last seventy years, the world has become increasingly urban, and the peasant way of life—the dominant way of life for humanity since agriculture began well over 6,000 years ago—is disappearing. In this new history of peasantry, social historian Patrick Joyce aims to tell the story of this lost world and its people, and how we can commemorate their way of life.
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Throughout history, two perspectives on the world have dueled in our minds: the extrinsic—that of mechanism and physics—and the intrinsic—that of feelings, thoughts, and ideas. The intrinsic perspective allows us to tell stories about our lives, to chart our anger and our lust, to understand our psychologies. The extrinsic allows us to chart the physical world, to build upon it, and to travel across it. These perspectives have never been reconciled; they almost seem to exist on different planes of thought.
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An insightful overview of consciousness research
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What Beach Boys' song brings Paul McCartney to tears? What makes "Light My Fire" a rite-of-passage song for teens in every generation, according to Doors guitarist Robby Krieger? What is it about music that brings back so vividly the passion of our early loves, our adult losses, our richest memories? In Anthems We Love, acclaimed music journalist Steve Baltin explores twenty-nine iconic songs through interviews with artists about their creative process and what songs form the soundtracks to their own lives.
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Every Chapter was Great
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Although half of the population, women were treated as second class citizens in the United States and denied the fundamental right to vote. In 1872, Susan B. Anthony dared to cast her vote in a national election. She was arrested, tried, and convicted of the crime of "voting without having a lawful right to vote". This thrilling, firsthand account from suffragist Doris Stevens details the organized protests that hundreds of courageous women from across the country undertook in DC between 1913 and 1919, as well as the brutal consequences they had to endure.
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History from someone who lived it!
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What listeners say about Biography of Resistance
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- Wil D
- 08-20-20
This is Something We All Need to Pay Attention to
The Biography of Resistance is a thoroughly researched book filled with information of how we have arrived at the edge of being overrun by antibiotic resistant bacteria. Muhammad Zaman does a deep dive into the history of antibiotics, and how bacteria are rapidly adapting to them. Additionally, he explains, while we need the research more than ever, why pharmaceutical companies are bailing out of antibiotic research and development. After reading this you'll have an excellent picture of what this this problem consists of and what needs to be done to overcome it.
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- Michael Curran
- 03-01-21
Robust chronicle of the growth of AMR
I appreciated the indepth discussion regarding the growth of AMR; the highlights of which I was familiar with, not the background.
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- Anonymous User
- 05-03-20
Excellent read for a complicated issue
The author broke down the subject of antimicrobial resistance to make it easy to understand, not only the science but the history and socioeconomic intricacies associated with the subject.
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- Sumguynobuddynoes
- 08-29-21
The next Extinction Level Event may be inevitable.
But nothing catastrophic or immediate. But mother nature catching up to our frail bodies when bacteria becomes the dominant lifeform on earth. Exit homosapiens. Scary if we do not find the secret to combat these persistent creatures. We may simply run out of ways to stop them. Meaning, even a simple infection could mean a death sentence.
I hope the scientific world realizes how important this situation has become. There is no profit when the expense of treatment is pitted against saving human life. So drug companies are not interested in losing money and dropping the anti-biotic research.
I guess mother nature may adapt a few of us to defending these deadly fiends so we may not die out after all. Hopefully we will learn their secret before it is too late.
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- zydeco
- 02-13-21
interesting journey
Feel like I'll need to go back and reread this book in hard copy. It was almost like taking a university course- but a very fascinating one.
Loved how it was broken up. Had some trouble following names of the people involved.
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- Ron
- 11-18-20
Good medical education for everyone
This book is possibly even more relevant in these COVID-19 times. Although it deals almost entirely with bacteria and not viruses, this is still a very good book to educate readers about the complexities of immunology and medical research, and the paramount importance of science to solve our current problems.
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5 people found this helpful
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- RI Shopper
- 10-13-23
Parts were interesting but narration not so much
I can’t really remember the book. Parts were informative and interesting. The reader/narrator was really terrible. I’m thinking it was artificial intelligence? It was so drone like. If it was a real human I apologize for being unkind.
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- Jake
- 06-09-22
90% history, 10% how it works
Overall, it is a good summary of the history regarding antibiotics and the research surrounding it. It is not so much a description of how antibiotics work, which although it touches upon it, does not focus on it.
I do find this author struggles with leaving his opinion out of what should be objective facts. He touches upon a variety of topics and events in history and describes everything as if it boils down to a dichotomy of good vs evil. For example, when touching upon people who overdose on drugs, he describes how the drug makers deserve 100% of the blame, and drug users 0%. He then ends that story and moves onto the next one. Is that objective, or even necessary? Rather than ending at “this is what went wrong with the drug,” he goes beyond to “this is who I blame if this was me.” The author does this repeatedly, and seemingly inadvertently. When he does describe dissenting viewpoints, he does a really poor job giving an accurate description of what the other side must have felt, giving an overly simplistic “well they were evil so they disagreed” explanation.
There is plenty of information to be learned from this book, I just think it could have been edited better.
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- J. Herbruck
- 04-13-24
Humanity with all its brains could easily be taken out by microbes with no brains
Very informative and extremely detailed about the story of the rise of microbial resistance and its importance for all living creatures. Exceedingly enlightening.
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- Jessie
- 11-01-23
A Must Read
Fascinating material, and incredibly frightening. This should be required reading, especially for doctors. Highly recommend.
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