For two thousand years, cadavers have been involved in science's boldest strides and weirdest undertakings. They've tested France's first guillotines, ridden the NASA Space Shuttle, been crucified in a Parisian laboratory to test the authenticity of the Shroud of Turin, and helped solve the mystery of TWA Flight 800. For every new surgical procedure, from heart transplants to gender reassignment surgery, cadavers have been there alongside surgeons, making history in their quiet way.

Backbone is a life-fulfilling message about managing chronic pain and living a life of purpose. For two decades, Karen Duffy, New York Times bestselling author, former MTV VJ, Revlon model, and actress, has managed to live an enriching life despite living in a state of constant pain. In this powerful, inspirational, funny, and important manual for surviving pain, Duffy draws on her experience as a patient advocate, trained recreational therapist, and hospice chaplain to illuminate gratifying methods people can use to cope with chronic pain.

With poignant insight and humor, Frank Vertosick, Jr., MD, describes some of the greatest challenges of his career, including a six-week-old infant with a tumor in her brain, a young man struck down in his prime by paraplegia, and a minister with a .22-caliber bullet lodged in his skull. Told through intimate portraits of Vertosick's patients and unsparing-yet-fascinatingly detailed descriptions of surgical procedures, When the Air Hits Your Brain illuminates both the mysteries of the mind and the realities of the operating room.

A hilarious and emotional personal account of the life, times, mistakes, and crippling codependence of comedian, producer, director, actress, and writer Whitney Cummings. Full of intellect, pathos, and profundity, I'm Fine...and Other Lies is, in Whitney's words, her first book, which means her last date. With her signature incendiary edge and self-deprecation, Whitney comes clean about what has shaped her into the trailblazing comic that she is today.

Sometimes in medicine the only way to know what is truly going on in a patient is to operate, to look inside with one's own eyes. This book is exploratory surgery on medicine itself, laying bare a science not in its idealized form but as it actually is - complicated, perplexing, and profoundly human.

America's Angriest Trainer, Vinnie Tortorich, exposes the nasty underbelly of the fitness industry while getting you into the best shape of your life. For over 20 years, Vinnie has been Hollywood's go-to guy for celebrities and athletes looking to get fit fast. Now, in this hilarious and often R-rated memoir, he holds nothing back. What's the best piece of fitness equipment money can buy? What's the fastest way to lose weight: diet or exercise? Why are health clubs worse than used car lots? In Fitness Confidential, Vinnie tells all.

When 24-year-old Susannah Cahalan woke up alone in a hospital room, strapped to her bed and unable to move or speak, she had no memory of how she’d gotten there. Days earlier, she had been on the threshold of a new, adult life: At the beginning of her first serious relationship and a promising career at a major New York newspaper. Now she was labeled violent, psychotic, a flight risk. What happened?

Rapper and singer Dessa gives a candid account of her life as a touring musician, her determination to beat long odds to make a name for herself, and her struggle to fall out of love with someone in her band. Raw and intimate, Dessa demonstrates just how far the mind can travel while the body is on the six-hour ride to the next rap show. Dessa finds unconventional approaches to all of her subjects - braiding her lived experience with academic research and a poet's tone and timing. In the vein of thinkers who defy categorization, we get the debut of a deft, likable, and unusual voice.

Dr. Kathy Magliato is one of fewer than a dozen female heart surgeons practicing in the world today. She is also a member of an even more exclusive group - those surgeons who perform heart transplants. Healing Hearts is the story of the making of a surgeon who also calls herself a wife and mother.

Tumors, injuries, ruptured vascular malformations—there is almost no such thing as a non-urgent brain surgery when it comes to kids. For a pediatric neurosurgeon working in the medical minefield of the brain—in which a single millimeter in every direction governs something that makes us essentially human—every day presents the challenge, and the opportunity, to give a new lease on life to a child for whom nothing is yet fully determined and all possibilities still exist.

In 1972, at the age of 21, John Callahan was involved in a car crash that severed his spine and made him a quadriplegic. A heavy drinker since the age of 12, the accident could have been the beginning of a downward spiral. Instead, it sparked a personal transformation. After extensive physical therapy, he was eventually able to grasp a pen in his right hand and make rudimentary drawings. By 1978, Callahan had sworn off drinking for good and begun to draw cartoons. Over the next three decades, Callahan would become one of the nation's most beloved cartoonists.

Julia Fox Garrison refused to listen to the professionals she called Dr. Jerk and Dr. Panic, who - after she suffered a massive, debilitating stroke at age thirty-seven - told her she’d probably die, or to Nurse Doom, who ignored her emergency call button. Instead she heeded the advice of kind, gifted Dr. Neuro, who promised her he would “treat your mind as well as your body.” Julia figured if she could somehow manage to get herself into a wheelchair, at least she’d always find parking. But after many, many months of hospitalization and rehab, Julia not only got into a wheelchair, but she got back out.

Whether it's family history, religion, aging, or his parents, Michael Ian Black always has something to say in the dry, irreverent voice that has captured a fan base of millions. When a medical diagnosis forces him to realize he's not getting any younger, he reexamines his life as a middle-aged guy - of course, in the deadpan wit and self-deprecating vignettes that have become trademarks of his humor.

A. J. Jacobs tackles his most challenging experiment yet: a yearlong mission to radically improve every element of his body and mind - from his brain to his fingertips to his abs. First, he had to tackle a complicated web of diet and exercise advice, most which is nonsensical, unproven, and contradictory. Second, he had to consult a team of medical advisers. And finally, he had to subject himself, over the course of two years, to a grueling regimen of exercises and a range of diets and nutritional plans.

It was a beautiful fall day in Connecticut when Colleen Kelly Alexander, a lifelong athlete, rode her bike home from work. She had survived both a diagnosis of lupus and brain surgery, had a fulfilling career, and was married at last to the love of her life. Everything was good as she coasted along, meeting the eyes of a truck driver as he approached the stop sign beside her. He didn't stop. The truck hit Colleen, running over her lower body with front and back tires and dragging her across the pavement.