Empire of Pain
The Secret History of the Sackler Dynasty
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Narrated by:
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Patrick Radden Keefe
About this listen
National Book Critics Circle Nominee
A New York Times Notable Book of the Year
New York Times best seller
A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. From the prize-winning and best-selling author of Say Nothing
The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom maneuvers; and the calculated use of money to burnish reputations and crush the less powerful. The Sackler name has adorned the walls of many storied institutions—Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and the sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis.
Empire of Pain begins with the story of three doctor brothers, Raymond, Mortimer, and the incalculably energetic Arthur, who weathered the poverty of the Great Depression and appalling anti-Semitism. Working at a barbaric mental institution, Arthur saw a better way and conducted groundbreaking research into drug treatments. He also had a genius for marketing, especially for pharmaceuticals, and bought a small ad firm.
Arthur devised the marketing for Valium, and built the first great Sackler fortune. He purchased a drug manufacturer, Purdue Frederick, which would be run by Raymond and Mortimer. The brothers began collecting art, and wives, and grand residences in exotic locales. Their children and grandchildren grew up in luxury.
Forty years later, Raymond’s son Richard ran the family-owned Purdue. The template Arthur Sackler created to sell Valium—co-opting doctors, influencing the FDA, downplaying the drug’s addictiveness—was employed to launch a far more potent product: OxyContin. The drug went on to generate some 35 billion dollars in revenue, and to launch a public health crisis in which hundreds of thousands would die.
This is the saga of three generations of a single family and the mark they would leave on the world, a tale that moves from the bustling streets of early 20th-century Brooklyn to the seaside palaces of Greenwich, Connecticut, and Cap d’Antibes to the corridors of power in Washington, DC. Empire of Pain chronicles the multiple investigations of the Sacklers and their company, and the scorched-earth legal tactics that the family has used to evade accountability.
Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling. It is a portrait of the excesses of America’s second Gilded Age, a study of impunity among the super elite and a relentless investigation of the naked greed and indifference to human suffering that built one of the world’s great fortunes.
©2021 Patrick Radden Keefe (P)2021 Random House AudioListeners also enjoyed...
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Critic reviews
New York Times Book Review 100 Notable Books of the Year • One of The Washington Post's 10 Best Books of the Year • TIME Magazine 100 Must Read Books of 2021 • One the Best Books of the Year: NPR, Slate, EW, Boston Globe, Goodreads, The Guardian, Town & Country, BuzzFeed, LitHub, Vulture, and more
Winner of the Baillie Gifford Prize for Non-Fiction and Finalist for the Baillie Gifford Winner of Winners Award
One of President Obama's Favorite Books of the Year
“An engrossing (and frequently enraging) tale of striving, secrecy and self-delusion….Keefe nimbly guides us through the thicket of family intrigues and betrayals… Even when detailing the most sordid episodes, Keefe’s narrative voice is calm and admirably restrained, allowing his prodigious reporting to speak for itself. His portrait of the family is all the more damning for its stark lucidity.”—Jennifer Szalai, The New York Times
“I read everything he writes. Every time he writes a book, I read it. Every time he writes an article, I read it … he’s a national treasure.”—Rachel Maddow, host of MSNBC’s “The Rachel Maddow Show” and author of the #1 New York Times bestselling Blowout
“A true tragedy in multiple acts. It is the story of a family that lost its moorings and its morals… Written with novelistic family-dynasty and family-dynamic sweep, EMPIRE OF PAIN is a pharmaceutical FORSYTHE SAGA, a book that in its way is addictive, with a page-turning forward momentum.”—David M. Shribman, The Boston Globe
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By: Geoffrey Cain
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The Organ Thieves
- The Shocking Story of the First Heart Transplant in the Segregated South
- By: Chip Jones
- Narrated by: JD Jackson
- Length: 12 hrs and 41 mins
- Unabridged
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In 1968, Bruce Tucker, a Black man, went into Virginia’s top research hospital with a head injury, only to have his heart taken out of his body and put into the chest of a White businessman. Now, in The Organ Thieves, Pulitzer Prize-nominated journalist Chip Jones exposes the horrifying inequality surrounding Tucker’s death and how he was used as a human guinea pig without his family’s permission or knowledge.
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Not your story to tell
- By Bianca S on 11-22-20
By: Chip Jones
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The Bettencourt Affair
- The World's Richest Woman and the Scandal That Rocked Paris
- By: Tom Sancton
- Narrated by: Amanda Carlin
- Length: 13 hrs and 51 mins
- Unabridged
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Overall
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Performance
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Story
Heiress to the nearly 40-billion-dollar L’Oréal fortune, Liliane Bettencourt was the world’s richest woman and the 14th wealthiest person. But her gilded life took a dark yet fascinating turn in the past decade. At 94, she was embroiled in what has been called the Bettencourt Affair, a scandal that dominated the headlines in France. Why? It’s a tangled web of hidden secrets, divided loyalties, frayed relationships, and fractured families, set in the most romantic city - and involving the most glamorous industry - in the world.
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A Juicy Chronicle
- By Jean on 10-24-17
By: Tom Sancton
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Targeted
- The Cambridge Analytica Whistleblower's Inside Story of How Big Data, Trump, and Facebook Broke Democracy and How It Can Happen Again
- By: Brittany Kaiser
- Narrated by: Brittany Kaiser
- Length: 13 hrs and 2 mins
- Unabridged
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Overall
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Performance
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In this explosive memoir, a political consultant and technology whistleblower reveals the disturbing truth about the multi-billion-dollar data industry, revealing to the public how companies are getting richer using our personal information and exposing how Cambridge Analytica exploited weaknesses in privacy laws to help elect Donald Trump - and how this could easily happen again in the 2020 presidential election.
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Heavy on Kaiser, Light on Cambridge Analytica’s Data Operations
- By Morgan H Hoban on 11-05-19
By: Brittany Kaiser
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Red Roulette
- An Insider's Story of Wealth, Power, Corruption, and Vengeance in Today's China
- By: Desmond Shum
- Narrated by: Tim Chiou
- Length: 9 hrs and 21 mins
- Unabridged
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Overall
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Performance
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Story
As Desmond Shum was growing up impoverished in China, he vowed his life would be different. Through hard work and sheer tenacity he earned an American college degree and returned to his native country to establish himself in business. There, he met his future wife, the highly intelligent and equally ambitious Whitney Duan who was determined to make her mark within China’s male-dominated society. Whitney and Desmond formed an effective team and, aided by relationships they formed with top members of China’s Communist Party, the so-called red aristocracy.
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Desmond Shum is not a rube! He knows about wine, ok?
- By Peter L Hansen on 10-06-21
By: Desmond Shum
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Where You Are Is Not Who You Are
- A Memoir
- By: Ursula Burns
- Narrated by: Ursula Burns
- Length: 7 hrs and 39 mins
- Unabridged
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The first Black female CEO of a Fortune 500 company looks back at her life and her career at Xerox, sharing unique insights on American business and corporate life, the workers she has always valued, racial and economic justice, how greed is threatening democracy, and the obstacles she’s conquered being Black and a woman.
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Relatable story, flaws and all
- By Anonymous User on 01-06-22
By: Ursula Burns
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How Chuck Feeney Made and Gave Away a Fortune
- The Billionaire Who Wasn't
- By: Conor O'Clery
- Narrated by: Erik Synnestvedt
- Length: 16 hrs
- Unabridged
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Overall
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In 1988 Forbes magazine hailed Chuck Feeney as the 23rd richest American alive. No one knew until then that he was extremely wealthy. Or was he? Born during the Depression in Elizabeth, New Jersey, Feeney had made a fortune as co-founder of Duty Free Shoppers, the world's largest duty-free retail chain. How he did it is one of the great untold retail stories of modern times. The greater untold story is that Feeney had in fact given away his fortune, in its totality, to endow Atlantic Philanthropies - one of the most generous and secretive philanthropic funds in the world.
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Horizons I never knew were there!
- By DTU_Garza on 08-13-17
By: Conor O'Clery
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Enabling Acts
- The Hidden Story of How the Americans With Disabilities Act Gave the Largest US Minority Its Rights
- By: Lennard Davis
- Narrated by: Kevin Stillwell
- Length: 10 hrs and 55 mins
- Unabridged
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Overall
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The first significant book on the history and impact of the ADA - the "eyes on the prize" moment for disability rights. The Americans with Disabilities Act (ADA) is the widest-ranging and most comprehensive piece of civil rights legislation ever passed in the United States, and it has become the model for disability-based laws around the world. Yet the surprising story behind how the bill came to be is little known.
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this book is so informative
- By Anonymous User on 01-10-23
By: Lennard Davis
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Mike Bloomberg
- Money, Power, Politics
- By: Joyce Purnick
- Narrated by: Mark Moseley
- Length: 6 hrs and 43 mins
- Unabridged
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Overall
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Story
Michael Bloomberg is not only New York City's 108th mayor; he is a business genius and self-made billionaire. He has run the toughest city in America with an independence and show of ego that first brought him great success and eventually threatened it. Yet while Bloomberg is internationally known and admired, few people know the man behind the carefully crafted public persona.
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Not the most captivating, but a decent summary
- By liz w on 03-06-17
By: Joyce Purnick
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US of AA
- How the Twelve Steps Hijacked the Science of Alcoholism
- By: Joe Miller
- Narrated by: Sean Patrick Hopkins
- Length: 6 hrs and 41 mins
- Unabridged
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Five years in the making, this brilliant, in-depth investigative reporting on the history, politics, and science of alcoholism will show how AA became our nation's de facto treatment policy, even as evidence for more effective remedies accumulated. US of AA is a character-driven, beautifully written exposé, full of secrecy, irony, liquor industry money, the shrillest of scare tactics and, at its center, a grand deception. US of AA shines a much-needed spotlight on the addiction treatment industry. It will forever change the way we think about the entire enterprise.
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A Detailed History of Alcoholism
- By Tricia O. on 04-03-19
By: Joe Miller
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The Last Lone Inventor
- A Tale of Genius, Deceit, and the Birth of Television
- By: Evan I. Schwartz
- Narrated by: Eric Jason Martin
- Length: 10 hrs and 16 mins
- Unabridged
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In a story that is both of its time and timeless, Evan I. Schwartz tells a tale of genius versus greed, innocence versus deceit, and independent brilliance versus corporate arrogance. Many men have laid claim to the title "father of television," but Philo T. Farnsworth is the true genius behind what may be the most influential invention of our time. Driven by his obsession to demonstrate his idea, by the age of 20 Farnsworth was operating his own laboratory above a garage in San Francisco and filing for patents. The resulting publicity caught the attention of RCA tycoon David Sarnoff, who became determined to control television in the same way he monopolized radio.
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Thank you, Philo.
- By JPALJ on 03-29-20
By: Evan I. Schwartz
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"The Rest of Us"
- The Rise of America's Eastern European Jews
- By: Stephen Birmingham
- Narrated by: Mel Foster
- Length: 18 hrs and 2 mins
- Unabridged
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Performance
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Story
The wave of Eastern European Jewish immigrants who swept into New York in the late nineteenth and early twentieth centuries by way of Ellis Island were not welcomed by the Jews who had arrived decades before. These refugees from czarist Russia and the Polish shtetls who came to America to escape pogroms and persecution were considered barbaric, uneducated, and too steeped in the traditions of the "old country" to be accepted by the more refined and already well-established German-Jewish community. But the new arrivals were tough, passionate, and determined.
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Book 3 of 3
- By Etoile NEOhio on 11-15-22
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The LEGO Story
- How a Little Toy Sparked the World’s Imagination
- By: Jens Andersen
- Narrated by: Peter Cross
- Length: 11 hrs and 50 mins
- Unabridged
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Overall
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Performance
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Story
It’s estimated that each year between eighty and ninety million children around the globe are given a box of LEGO, while up to ten million adults buy sets for themselves. Yet LEGO is much more than a dizzying number of plastic bricks that can be put together and combined in countless ways. LEGO is also a vision of the significance of what play can mean for humanity.
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Great book! Don't miss this
- By hgpilot - MM on 04-27-23
By: Jens Andersen
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How Money Became Dangerous
- The Inside Story of Our Turbulent Relationship with Modern Finance
- By: Christopher Varelas, Dan Stone
- Narrated by: Roger Wayne
- Length: 14 hrs and 43 mins
- Unabridged
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Performance
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From a veteran of the trade, a provocative and entertaining voyage into the turbulent heart of modern money that sheds new light on the rise of our threatening and complicated financial system, how money became our adversary, and why finding a new course is crucial to a healthy society.
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Must read
- By Craig M. Stratton on 02-08-20
By: Christopher Varelas, and others
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Dirty Work
- Essential Jobs and the Hidden Toll of Inequality in America
- By: Eyal Press
- Narrated by: Neil Shah
- Length: 11 hrs and 18 mins
- Unabridged
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Drone pilots who carry out targeted assassinations. Undocumented immigrants who man the "kill floors" of industrial slaughterhouses. Guards who patrol the wards of America's most violent and abusive prisons. In Dirty Work, Eyal Press offers a paradigm-shifting view of the moral landscape of contemporary America through the stories of people who perform society's most ethically troubling jobs. As Press shows, we are increasingly shielded and distanced from an array of morally questionable activities that other, less privileged people perform in our name.
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A Must Read for Conservatives
- By Nice guy on 11-05-21
By: Eyal Press
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Infuriating and Compelling
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In the late 1990s, when Keefe was a graduate student in England, he heard stories about an eavesdropping network led by the United States that spanned the planet. The system, known as Echelon, allowed America and its allies to intercept the private phone calls and e-mails of civilians and governments around the world.
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Essential reading for sceptics of
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In 1929, in the blue-collar city of Portsmouth, Ohio, a company built a swimming pool the size of a football field; named Dreamland, it became the vital centre of the community. Now, addiction has devastated Portsmouth, as it has hundreds of small rural towns and suburbs across America—addiction like no other the country has ever faced. How that happened is the riveting story of Dreamland.
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One in three American children will be arrested by the time they are 23, and many will spend time locked inside horrific detention centers that defy everything we know about what motivates young people to change. Nell Bernstein argues that there is no right way to lock up a child. A landmark book, Burning Down the House sparked a national conversation about our inhumane and ineffectual juvenile prisons, and ultimately makes the radical argument that the only path to justice is for state-run detention centers to be abolished completely.
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Chatter
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In this extraordinary work, Beth Macy takes us into the epicenter of a national drama that has unfolded over two decades. From the labs and marketing departments of big pharma to local doctor's offices; wealthy suburbs to distressed small communities in Central Appalachia; from distant cities to once-idyllic farm towns; the spread of opioid addiction follows a tortuous trajectory that illustrates how this crisis has persisted for so long and become so firmly entrenched.
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Useful, but recommend Dreamland instead
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When Crack Was King
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The crack epidemic of the 1980s and 1990s is arguably the least examined crisis in American history. Beginning with the myths inspired by Reagan’s war on drugs, journalist Donovan X. Ramsey’s exacting analysis traces the path from the last triumphs of the Civil Rights Movement to the devastating realities we live with today: a racist criminal justice system, continued mass incarceration and gentrification, and increased police brutality.
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Done by Design
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Don and Mimi Galvin seemed to be living the American dream. After World War II, Don's work with the Air Force brought them to Colorado, where their 12 children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the 10 Galvin boys, one after another, were diagnosed as schizophrenic.
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American Kingpin
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In 2011, a 26-year-old libertarian programmer named Ross Ulbricht launched the ultimate free market: the Silk Road, a clandestine website hosted on the Dark Web where anyone could trade anything - drugs, hacking software, forged passports, counterfeit cash, poisons - free of the government's watchful eye. It wasn't long before the media got wind of the new website where anyone - not just teenagers and weed dealers but terrorists and black hat hackers - could buy and sell contraband detection-free.
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An honest portrait of DPR
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El imperio del dolor [Empire of Pain]
- La historia secreta de la dinastía que reinó en la industria farmacéutica [The Secret History of the Dynasty That Reigned in the Pharmaceutical Industry]
- By: Patrick Radden Keefe, Francesc Pedrosa Martín - translator, Luis Jesús Negro García - translator, and others
- Narrated by: Jordi Salas
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- Unabridged
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Overall
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Performance
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El retrato demoledor de una dinastía cuya fortuna se construyó gracias a Valium y cuya reputación fue destruida por OxyContin.
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Extraordinario
- By Frank Lopez Ballesteros on 07-13-23
By: Patrick Radden Keefe, and others
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Bad Blood
- Secrets and Lies in a Silicon Valley Startup
- By: John Carreyrou
- Narrated by: Will Damron
- Length: 11 hrs and 37 mins
- Unabridged
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Story
In 2014, Theranos founder and CEO Elizabeth Holmes was widely seen as the next Steve Jobs: a brilliant Stanford dropout whose startup “unicorn” promised to revolutionize the medical industry with its breakthrough device, which performed the whole range of laboratory tests from a single drop of blood. Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at more than $9 billion, putting Holmes’s worth at an estimated $4.5 billion.
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Extreme retaliation against former employees
- By LEE on 05-29-18
By: John Carreyrou
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While You Were Out
- An Intimate Family Portrait of Mental Illness in an Era of Silence
- By: Meg Kissinger
- Narrated by: Meg Kissinger
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Growing up in the 1960s in the suburbs of Chicago, Meg Kissinger’s family seemed to live a charmed life. With eight kids and two loving parents, the Kissingers radiated a warm, boisterous energy. Whether they were spending summer days on the shores of Lake Michigan, barreling down the ski slopes, or navigating the trials of their Catholic school, the Kissingers always knew how to live large and play hard. But behind closed doors, a harsher reality was unfolding.
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Thoughtful and mindful
- By James Thomas McIntyre on 09-11-23
By: Meg Kissinger
What listeners say about Empire of Pain
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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Overall
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- Elizabeth Lund
- 04-18-21
MUST READ... you need to know who the Sackler family is
Mr Keefe gives a very informative story with a clear insight to a family that most of us had never heard of. The Sackler family hid behind their pharmaceutical company Purdue Pharma, making billions of dollars, knowing that people were becoming addicted to their OxyContin that they sold. The Sacklers’ did not have a care in the world that people were dying everyday because of their drug that caused the opioid crisis. The Sacklers’ just continued on living the high life at the expense of other families. Mr Keefe opens your eyes to the corruption that goes on with the pharmaceutical industry and how people with money are offered a different justice then the rest of us. A true tragedy that could have and should have been stopped years before.
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64 people found this helpful
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- Candy
- 04-21-21
Definitely a Must Read!
One of the best non fiction books I've read. The story of the 3 arrogant generations associated with the opioid crisis is eye opening.
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37 people found this helpful
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- aaron
- 05-08-21
About as fair a shake as they're gonna get
This book is incredibly well researched. Keefe is also an above average storyteller. If you have any interest in how the Oxycontin epidemic began, you need to read this.
It's sorta remarkable, the access he had to various sources. I'm still trying to wrap my head around how he compiled everything into just on book.
Regardless, this is probably one of the most important stories of the last fifty years that hardly any Americans know about. That fact alone justifies its value. Keefe does a good job narrating as well.
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6 people found this helpful
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- Rachel
- 05-05-21
RIVETING!!!!!
This is one of the best books I've read/listened to in a long time. From the very beginning, I was hooked and basically binge-listened to it. I highly recommend it for the story and I feel that the author did an amazing job at the narration too. It's a must read that I'm telling everyone I know about.
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- Jim Higgins
- 05-01-21
Empire of Pain
Great book and so well documented. Enjoyed every minute Highly recommend this read as it is full of sound information 😍
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- Linda
- 04-25-21
Outstanding well researched and thorough. A 10 on a scale of 5
This is an outstanding book about the Sackler family and their rise and fall. Keefe is a masterful writer, telling a factual story while also placing it in a powerful narrative. He
Is research is astonishing, and his final gift to the nation will be that this timeline will make it easier to evaluate all of the information which will come out about this astonishingly venal family.
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- Libby Hartman
- 04-03-23
Must read.
Cutting no corners and pulling no punches Keefe weaves an honest tale of greed and money.
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- STEVEN C. ANDERSON
- 10-13-22
Unfortunately an integral part of advertising & pharmaceuticals
Don’t let my 3 star performance sway you from this unbelievable 4 generation history of family dynasty. There’s soap opera worthy details of selfish family values & ambitious greed. Every American should read this purely to have a better understanding of what they’re putting in there bodies & why OUTSIDE sources matter (NOT the FDA, ADVERTISING (doctors), even TEXT BOOKS! Always look & see who is producing, donating, supporting, & where did employees previously work!
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- Megan
- 12-20-21
Extremely well researched and presented
This was an infuriating read of obscenely rich people doing terrible things and buying their way out with high priced lawyers, but despite that it was fascinating. The author was thorough and thoughtful, and I enjoyed it as much as I could for how angry I was.
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- EyeBurn
- 09-04-21
You don't know what you don't know
I of course knew about opioids and opioid addiction and the crisis in this country, particularly the Appalachian regions, but I never had any idea of the makers, the history, or the aggressive sales tactics. I am glad I picked this up. Great narration!
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