We all know that without water we couldn't survive, and that sometimes a cup of coffee or a glass of wine feels just as vital. But do we really understand how much we rely on liquids, or the destructive power they hold? Set over the course of a flight from London to San Francisco, Liquid Rules offers listeners a fascinating tour of these formless substances, told through the language of molecules, droplets, heartbeats, and ocean waves.

Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

Dame Sue Black is an internationally renowned forensic anthropologist and human anatomist. She has lived her life eye to eye with the Grim Reaper, and she writes vividly about it in this book, which is part primer on the basics of identifying human remains, part frank memoir of a woman whose first paying job as a schoolgirl was to apprentice in a butcher shop, and part no-nonsense but deeply humane introduction to the reality of death in our lives. It is a treat for CSI junkies, murder mystery and thriller fans, and anyone seeking a clear-eyed guide to a subject that touches us all.

Author Brian Switek is a charming and enthusiastic osteological raconteur. In this natural and cultural history of bone, he explains where our skeletons came from, what they do inside us, and what others can learn about us when these wondrous assemblies of mineral and protein are all we've left behind.

We prefer not to talk about it, but we should. Disease spread by waste kills more people worldwide every year than any other single cause of death. Even in America, nearly two million people have no access to an indoor toilet. Yet the subject remains unmentionable. Moving from the underground sewers of Paris, London, and New York (an infrastructure disaster waiting to happen) to an Indian slum where ten toilets are shared by 60,000 people, The Big Necessity breaks the silence, revealing everything that matters about how people do - and don't - deal with their own waste.

Mrs. Grace Humiston was an amazing lawyer and a traveling detective during a time when no women were practicing those professions. She focused on solving cases no one else wanted and advocating for innocents. One of her greatest accomplishments was solving the cold case of a missing 18-year-old girl, Ruth Cruger. Her work changed how the country viewed the problem of missing girls, but it came with a price: she learned all too well what happens when one woman upstages the entire NYPD.

In Proof, Adam Rogers reveals alcohol as a miracle of science, going deep into the pleasures of making and drinking booze—and the effects of the latter. The people who make and sell alcohol may talk about history and tradition, but alcohol production is really powered by physics, molecular biology, organic chemistry, and a bit of metallurgy—and our taste for those products is a melding of psychology and neurobiology.

The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic medication. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.

It was heaven on earth—and, some whispered, the devil’s garden. Thousands came by trains and carriages to see this new Eden, carved from hundreds of acres of wild woodland. They marveled at orchards bursting with fruit, thick herds of Ayrshire cattle and Cotswold sheep, and whizzing mills. They gaped at the people who lived in this place—especially the women, with their queer cropped hair and shamelessly short skirts. The men and women of this strange outpost worked and slept together—without sin, they claimed.

The fascinating science and history of the air we breathe. It's invisible. It's ever present. Without it, you would die in minutes. And it has an epic story to tell. In Caesar's Last Breath, New York Times best-selling author Sam Kean takes us on a journey through the periodic table, around the globe, and across time to tell the story of the air we breathe, which, it turns out, is also the story of earth and our existence on it.

They destroy plant diseases. They break down toxins. They plough the earth. They transform forests. They’ve survived two mass extinctions, including the one that wiped out the dinosaur. Not bad for a creature that’s deaf, blind, and spineless. Who knew that earthworms were one of our planet’s most important caretakers? Or that Charles Darwin devoted his last years to studying their remarkable achievements?

Science is a force for good in the world—at least usually. But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn’t everything, it’s the only thing—no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process.

A magnificently reported and soulfully crafted exploration of the human immune system - the key to health and wellness, life and death. An epic, first-of-its-kind audiobook, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize-winning New York Times journalist.

For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight-how the same simple chemistry gives rise to life and causes our demise.

From 1337 to 1453 England repeatedly invaded France on the pretext that her kings had a right to the French throne. Though it was a small, poor country, England for most of those "100 years" won the battles, sacked the towns and castles, and dominated the war. Desmond Seward's critically acclaimed account of the Hundred Years War brings to life all of the intrigue, beauty, and royal to-the-death-fighting of that legendary century-long conflict.

The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic medication. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.

The universal instinct is to run from an outbreak of disease. These doctors run toward it. They always keep a bag packed. They seldom have more than 24 hours before they are dispatched. They are told only their country of destination and the epidemic they will tackle when they get there.

For 200 years, a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. What these strange conditions share is their cause: prions.

For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As cardiologist and best-selling author Sandeep Jauhar tells in The Heart, it was only recently that we demolished age-old taboos and devised the transformative procedures that changed the way we live. Deftly alternating between historical episodes and his own work, Jauhar tells the colorful and little known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ.

Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

In 1518, in a small town in Alsace, Frau Troffea began dancing and didn't stop. She danced until she was carried away six days later, and soon 34 more villagers joined her. Then more. In a month more than 400 people had been stricken by the mysterious dancing plague. In late-19th-century England an eccentric gentleman founded the No Nose Club in his gracious townhome - a social club for those who had lost their noses, and other body parts, to the plague of syphilis for which there was then no cure.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.

Feeling feverish, tired, or achy? Listening to Gina Kolata's engrossing account of the 1918 Influenza epidemic is sure to give you the chills. A gripping work of science writing, Flu addresses the prospects for a great epidemic recurring, and considers what can be done to prevent it.

David Oshinsky, whose last book, Polio: An American Story, was awarded a Pulitzer Prize, chronicles the history of America's oldest hospital and in so doing also charts the rise of New York to the nation's preeminent city, the path of American medicine from butchery and quackery to a professional and scientific endeavor, and the growth of a civic institution.

From evolution to the epidural and beyond, Tina Cassidy presents an intelligent, enlightening, and impeccably researched cultural history of how and why we're born the way we are. Women have been giving birth for millennia, but that's about the only constant in the final stage of the great process that is human reproduction. Why is it that every culture and generation seems to have its own ideas about the best way to give birth?

When avian flu began spreading across Asia in the early 2000s, it reawakened fears that had lain dormant for nearly a century. During the outbreak's deadliest years, Alan Sipress chased the virus as it infiltrated remote jungle villages and teeming cities and saw its mysteries elude the world's top scientists. In The Fatal Strain, Sipress details how socioeconomic and political realities in Asia make it the perfect petri dish in which the fast-mutating strain can become easily communicable among humans.

In the winter of 1918, at the height of World War I, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in 24 weeks than AIDS has killed in 24 years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision between modern science and epidemic disease.

On the 100th anniversary of the devastating pandemic of 1918, Jeremy Brown, a veteran ER doctor, explores the troubling, terrifying, and complex history of the flu virus, from the origins of the Great Flu that killed millions, to vexing questions such as: are we prepared for the next epidemic, should you get a flu shot, and how close are we to finding a cure?

Dr. Steven Hatch first came to Liberia in November 2013 to work at a hospital in Monrovia. Six months later, several of the physicians Dr. Hatch had mentored and served with were dead or barely clinging to life, and Ebola had become a world health emergency. Hundreds of victims perished each week; whole families were destroyed in a matter of days; so many died so quickly that the culturally taboo practice of cremation had to be instituted to dispose of the bodies.

This comprehensive and gripping narrative, which received the 2006 Pulitzer Prize for history, covers all the challenges, characters, and controversies in America's relentless struggle against polio. Funded by philanthropy and grassroots contributions, Salk's killed-virus vaccine (1954) and Sabin's live-virus vaccine (1961) began to eradicate this dreaded disease.

In this extraordinary work of narrative nonfiction, eight years in the making, sociologists Pamela Prickett and Stefan Timmermans uncover a hidden social world. They follow four individuals in Los Angeles, tracing the twisting, poignant paths that put each at risk of going unclaimed, and introducing us to the scene investigators, notification officers, and crematorium workers who care for them when no one else will.

Colin Dickey is on the trail of America's ghosts. Crammed into old houses and hotels, abandoned prisons and empty hospitals, the spirits that linger continue to capture our collective imagination, but why? His own fascination piqued by a house hunt in Los Angeles that revealed derelict foreclosures and "zombie homes", Dickey embarks on a journey across the continental United States to decode and unpack the American history repressed in our most famous haunted places.

In Out Cold, science writer Phil Jaekl chronicles the underappreciated story of human innovation with cold, from Ancient Egypt, where it was used to treat skin irritations, to 18th-century London, where scientists used it in their first explorations of suspended animation. Throughout history, physicians have used cold to innovate life extension, enable distant space missions, and explore consciousness.

Filled to the brim with far-out facts, this wickedly informative narrative from the author of National Geographic's popular Gory Details blog takes us on a fascinating journey through an astonishing new reality. Blending humor and journalism in the tradition of Mary Roach, acclaimed science reporter Erika Engelhaupt investigates the gross, strange, and morbid absurdities of our bodies and our universe.

In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of 19th-century surgery on the eve of profound transformation. She conjures up early operating theaters - no place for the squeamish - and surgeons, working before anesthesia, who were lauded for their speed and brute strength. They were baffled by the persistent infections that kept mortality rates stubbornly high. A young, melancholy Quaker surgeon named Joseph Lister would solve the deadly riddle and change the course of history.

The summer before his senior year in college, Greg Melville worked at the cemetery in his hometown, and thanks to hour upon hour of pushing a mower over the grassy acres, he came to realize what a rich story the place told of his town and its history. Thus was born Melville’s lifelong curiosity with how, where, and why we bury and commemorate our dead. Melville’s Over My Dead Body is a lively (pun intended) and wide-ranging history of cemeteries, places that have mirrored the passing eras in history but have also shaped it.

As new forms of lie detection gain momentum in the present day, Tremors in the Blood reveals the incredible truth behind the creation of the polygraph, through gripping true-crime cases featuring explosive gunfights, shocking twists, and high-stakes courtroom drama. Touching on psychology, technology, and the science of the truth, Tremors in the Blood is a vibrant, atmospheric thriller and a warning from history: beware what you believe.

Regina Martínez was no stranger to retaliation. A journalist out of Mexico’s Gulf Coast state of Veracruz, Regina's stories for the magazine Proceso laid out the corruption and abuse underlying Mexican politics. She was barred from press conferences, and copies of Proceso often disappeared before they made the newsstands. In 2012, shortly after Proceso published an article on corruption and two Veracruz politicians, and the magazine went missing once again, she was bludgeoned to death in her bathroom. The message was clear: No journalist in Mexico was safe.

As investigators brought out the bagged remains of several dozen young men from a small Chicago ranch home and paraded them in front of a crowd of TV reporters and spectators, attention quickly turned to the owner of the house. John Gacy was an upstanding citizen, active in local politics and charities, famous for his themed parties and appearances as Pogo the Clown. But in the winter of 1978-79, he became known as one of many so-called “sex murderers” who had begun gaining notoriety in the random brutality of the 1970s.

When Susannah Breslin is a toddler, her parents enroll her in an exclusive laboratory preschool at the University of California, Berkeley, where she becomes one of 128 children who are research subjects in an unprecedented 30-year psychological experiment that predicts who she and her cohort will grow up to be. Decades later, trapped in an abusive marriage to a man with a violent history and battling breast cancer, she starts to wonder how growing up under a microscope shaped the person she became and her life choices. Is she the narrator of the story of her life, or is something else?