Transformer
The Deep Chemistry of Life and Death
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Narrated by:
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Richard Trinder
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By:
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Nick Lane
About this listen
For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight-how the same simple chemistry gives rise to life and causes our demise.
Lane is among the vanguard of researchers asking why the Krebs cycle, the "perfect circle" at the heart of metabolism, remains so elusive more than eighty years after its discovery. Transformer is Lane's voyage, as a biochemist, to find the inner meaning of the Krebs cycle-why it is still spinning at the heart of life and death today.
Transformer unites the story of our planet with the story of our cells-what makes us the way we are, and how it connects us to the origin of life. Enlivened by Lane's talent for distilling and humanizing complex research, Transformer is a must-listen for anyone fascinated by biology's great mysteries. Life is at root a chemical phenomenon: this is its deep logic.
©2022 Nick Lane (P)2022 TantorListeners also enjoyed...
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What is the nature of the material world? How does it work? What is the universe and how was it formed? What is life? Where do we come from and how did we evolve? How and why do we think? What does it mean to be human? How do we know? There are many different versions of our creation story. This book tells the version according to modern science. It is a unique account, starting at the Big Bang and travelling right up to the emergence of humans as conscious intelligent beings, 13.8 billion years later.
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Interesting book, but WOW, the narrator ...
- By UH on 01-10-17
By: Jim Baggott
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A Little History of the World
- By: E. H. Gombrich
- Narrated by: Ralph Cosham
- Length: 9 hrs and 11 mins
- Unabridged
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E. H. Gombrich's world history, an international best seller now available in English for the first time, is a text dominated not by dates and facts but by the sweep of experience across the centuries, a guide to humanity's achievements, and an acute witness to its frailties.
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an enlightening book; very well read
- By A.B.Oxford on 06-03-06
By: E. H. Gombrich
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The Deeper Genome
- Why There Is More to the Human Genome than Meets the Eye
- By: John Parrington
- Narrated by: John Lee
- Length: 9 hrs
- Unabridged
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Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way.
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Great Scientific Writing/ Wrong Narrator
- By Richard on 11-24-15
By: John Parrington
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Life Unfolding
- How the Human Body Creates Itself
- By: Jamie A. Davies
- Narrated by: Napoleon Ryan
- Length: 9 hrs and 56 mins
- Unabridged
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Where did I come from? Why do I have two arms but just one head? How is my left leg the same size as my right one? Why are the fingerprints of identical twins not identical? How did my brain learn to learn? Why must I die? Questions like these remain biology's deepest and most ancient challenges. They force us to confront a fundamental biological problem: How can something as large and complex as a human body organize itself from the simplicity of a fertilized egg?
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Fascinating Biology ; Distracting Narration
- By Tim on 03-01-15
By: Jamie A. Davies
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What Is Life?
- How Chemistry Becomes Biology
- By: Addy Pross
- Narrated by: Derek Perkins
- Length: 6 hrs and 50 mins
- Unabridged
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Seventy years ago, Erwin Schrdinger posed a simple, yet profound, question: What is life?. How could the very existence of such extraordinary chemical systems be understood? This problem has puzzled biologists and physical scientists both before, and ever since. Living things are hugely complex and have unique properties, such as self-maintenance and apparently purposeful behaviour which we do not see in inert matter. So how does chemistry give rise to biology?
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Profound & Life Changing...
- By Daegan Smith on 04-06-15
By: Addy Pross
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The Science of Rick and Morty
- The Unofficial Guide to Earth's Stupidest Show
- By: Matt Brady
- Narrated by: Joe Hempel
- Length: 10 hrs and 27 mins
- Unabridged
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Blending biology, chemistry, and physics basics with accessible - and witty-prose, The Science of Rick and Morty equips you with the scientific foundation to thoroughly understand Rick's experiments from the show, such as how we can use dark matter and energy, just what is intelligence hacking, and whether or not you can really control a cockroach's nervous system with your tongue. Perfect for longtime and new fans of the show, this is the ultimate segue into discovering more about our complicated and fascinating universe.
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Some good science in here?
- By Darin Harbert on 02-06-20
By: Matt Brady
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The Blind Watchmaker
- Why the Evidence of Evolution Reveals a Universe Without Design
- By: Richard Dawkins
- Narrated by: Richard Dawkins, Lalla Ward
- Length: 14 hrs and 40 mins
- Unabridged
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The Blind Watchmaker, knowledgably narrated by author Richard Dawkins, is as prescient and timely a book as ever. The watchmaker belongs to the 18th-century theologian William Paley, who argued that just as a watch is too complicated and functional to have sprung into existence by accident, so too must all living things, with their far greater complexity, be purposefully designed. Charles Darwin's brilliant discovery challenged the creationist arguments; but only Richard Dawkins could have written this elegant riposte.
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Challenging textbook more than an enjoyable listen
- By Eric on 01-15-12
By: Richard Dawkins
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How to Build a Dinosaur
- Extinction Doesn't Have to Be Forever
- By: Jack Horner, James Gorman
- Narrated by: Patrick Lawlor
- Length: 6 hrs and 36 mins
- Unabridged
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In movies, in novels, in comic strips, and on television, we've all seen dinosaurs - or at least somebody's educated guess of what they would look like. But what if it were possible to build, or grow, a real dinosaur without finding ancient DNA? Jack Horner, the scientist who advised Steven Spielberg on the blockbuster film Jurassic Park and a pioneer in bringing paleontology into the 21st century, teams up with the editor of the New York Times's Science Times section to reveal exactly what's in store.
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Good book but misplaced title
- By Robert on 06-19-15
By: Jack Horner, and others
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A Series of Fortunate Events
- Chance and the Making of the Planet, Life, and You
- By: Sean B. Carroll
- Narrated by: Sean B. Carroll
- Length: 4 hrs and 48 mins
- Unabridged
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Why is the world the way it is? How did we get here? Does everything happen for a reason, or are some things left to chance? Philosophers and theologians have pondered these questions for millennia, but startling scientific discoveries over the past half century are revealing that we live in a world driven by chance. A Series of Fortunate Events tells the story of the awesome power of chance and how it is the surprising source of all the beauty and diversity in the living world.
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We are for a short time.
- By Anonymous User on 10-14-20
By: Sean B. Carroll
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The Powerhouse of the Cell: A Comprehensive Guide to Mitochondria" is an in-depth examination of the intricacies of these vital organelles. Written for both students and professionals in the field of biology. It covers the latest research and discoveries on the role of mitochondria in various physiological processes, including energy metabolism, cell growth and death, and aging. The book also explores the implications of mitochondrial dysfunction in various diseases such as cancer, neurodegenerative disorders, and metabolic disorders. This book provides an understanding of the complexity ...
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Block by Block offers an original perspective on thermodynamic science and history based on the three approaches of a practicing engineer, academician, and historian. The book synthesizes and gathers into one accessible volume a strategic range of foundational topics involving the atomic theory, energy, entropy, and the laws of thermodynamics.
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Incomplete
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Biochemistry
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Good Beginning
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What listeners say about Transformer
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Yael
- 11-14-22
Don’t miss out this essential book!
This is his s best book thus far! Despite my prior knowledge in the field and some disagreements with some of the author’s conclusions, this is a book that every scientist must read (or science buff). The author was able to explain each puzzle piece in order that when he connects it all to a larger picture, the reader will be in awe. Whether the day to day of a scientist that comes to a great discovery without recognition from his surroundings (can inspire and give hope in the darkest of times) or how the current knowledge especially in mitochondria is the essential key to explain many biological processes. A must have and read! (Thank you for this book)
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2 people found this helpful
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- Paul Hillery
- 12-07-22
Great Book for Geneticists and Microbiologists
This book was a little over my head, although the author's style and the narrator's voice drew me in to try the clouds eye view, and therefore I did get some grasp of the deep science of microbiology and genetics. AND a dislike of phages!
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- Anonymous User
- 12-28-23
Great synthesis of important aspects of biochemistry.
It was a little tough for me in audio book format so I bought the book to allow me to review in more detail. Love the topic and the writing style.
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- Gabriel Weiss
- 01-25-23
Excellent Exploration of the Krebs Cycle
If you love biochemistry and its relevance to understanding life and our place on this planet or even if you simply wish to contemplate how the dance of molecules might generate consciousness, then this is a must read!
The epilogue hints at what I hope will be the direction of Lane’s future writings. I recommend reading it before the rest of the book and then again at the end.
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- roger olsson
- 07-19-23
Great and interesting book, I learnt a lot
I really enjoyed this book; the reading was slow in the first two chapters (increasing the speed with 10% worked) but catched on after that.
I'm a little disappointed that the cool FAD small molecule is not mentioned in the electron transfers, FAD is really the electron donor in most cases not NADPH, the latter donates a hydride, while the FAD takes the hydride and split it into electrons and a proton.
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- Nate
- 07-11-23
A great story of life
I’m a computer scientist, physicist, and performing artist, and I found this book engaging and fascinating.
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- sam
- 09-27-22
Like his other books, superb
If you like biochemistry and metabolism, this is the book for you. Once you go deep in Krebs cycle you can not unsee it. Highly recommend book
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13 people found this helpful
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- robert
- 02-25-23
Are used immersive learning for this book it was excellent
This book taught me a lot. Are used immersive learning subscribing to the Audible and Kindle version. Although I studied bio chemistry years ago, I found that my ability to memorize exceeded my understanding. Nick Lane explains the concepts sometimes with speculation. But now I have much more understanding and appreciation for bio chemistry, and it’s wonders.
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- Bradley J farris
- 12-15-22
Great book but a difficult audiobook
This one is better to read rather than listen to, the dense science requires merits re-reading multiple sentences, the rewind button doesn’t quite have the same impact.
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- GoForItOldLady
- 12-08-22
Completely transformed my sense of being alive
I could only vaguely sense how the complicated biochemistry described by the author leads to glimpses into the possible chemical origins of life and all its complexity. [And by the way, he doesn’t dumb it down much for non-scientist readers (listeners) like me.] But I can no longer have quite the cavalier attitude to what I eat and do as I did before this book. The author’s descriptions of the transformations that must occur at the molecular level in our cells, that cause growth or death, have given me a new sense of astonishment about life itself. At the end, the author describes the transformations that he speculates might give rise to consciousness. I found it electrifying to learn and think about it all. And anyone who reads or listens to the book will appreciate the extra meaning in that description.
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1 person found this helpful