Liverpool, 1917. When Irish seaman Michael Gallagher docks in Liverpool after years of fighting with the British Navy, he never expects to fall in love. But the moment he glimpses Stella Bennett, all thoughts of returning to his homeland vanish. Determined to be together, the young couple defy Stella’s parents’ wishes. But their plans to marry are soon derailed by the arrival of baby Ginny. Her crop of fiery red hair plants a seed of doubt in her father’s mind, and it’s not long before their world begins to fall apart.

One wild night in the 1930s, midwife Patty Peel is called to attend a birth on the opposite side of Liverpool. She pedals off into the storm and delivers a baby girl in a filthy slum dwelling, just as the mother dies. The drunk and violent father tells Patty to get rid of it so she takes the child away, meaning to deliver it to the nearest orphanage. However, Patty spent her entire childhood in an institution, except for the frequent occasions when she ran away, and cannot bear to hand the baby over.

It's 1938, and Cadi is chosen to be Rose Queen in the annual Rose Fete. She is thrilled to be treated like royalty for the day. But deep down she is desperate to leave the Welsh mining community where she grew up. When war is declared, Cadi and her best friend, Poppy, see a chance to escape. Cadi leaves behind her parents and local boy Aled, whom she is meant to marry, for Liverpool.

Liverpool, 1939. As winter descends on Tuppenny Corner and rumours of war float across the canals, 15-year-old Rosie O’Leary must come to terms with her own dramatic upheaval. Forced to say good-bye to all she holds dear and embark on a new life aboard The Kingfisher, her world is suddenly full of uncertainty. But new beginnings open up new possibilities.... When fellow bargee Tim Bradley offers to show Rosie the sights of Liverpool, she jumps at the chance, and it’s not long before their friendship grows into something more.

December, 1938. Rozalin Sachs has grown up in the vibrant city of Frankfurt. But with the Nazi Revolution gaining power, her family is forced to flee Germany. When a tragic accident separates Roz from her parents, she finds herself aboard the Kindertransport bound for Holland. Here Roz meets a young lad called Felix, and they vow to stick together as their journey takes them to England. Eventually, they find themselves in Liverpool with the promise of a new life, until a devastating incident takes Felix away.

Lady Joanna Harcourt and her daughter, Sarah, discover their life of luxury at Goodwill House is over. Because with Lord Harcourt away fighting, the Harcourt girls are facing financial ruin. Lady Joanna is terrified of losing their home, but for Sarah, this means her dreams of becoming a doctor are over. Headstrong Sarah isn’t one to quit! War or not, she’s determined to find a way to save her home and follow her dreams - whatever it takes.

Following a humiliating experience involving the man she thought she’d marry, Iris Tredwick signs up to the Wrens in order to escape and - hopefully - find ‘the right sort’ of man to please her mother. After a bumpy start, Iris manages to befriend outspoken Mary and dreamer Sally as they are sent to their first posting - in Orkney. There she meets engineer Rob, whose flirtatious nature both charms and confounds straight-laced Iris. Much more appropriate for her is local doctor Stewart, if only she felt the same spark for him as she does for Rob.

When sixteen-year-old Sally is evacuated to the English south coast, she is terrified by what lies ahead of her. All she knows are the sights and sounds of London's East End – but Sally swallows her tears as they leave the familiar landmarks behind, knowing that she has to be a Grown-Up Girl and play mother to her six-year-old brother Ernie. Playing mother is nothing new for Sally – their real mother Florrie, a good-time girl, hasn't even come to the station to wave them off and Ernie, crippled at an early age by polio, is used to depending on his older sister.

Maggie Bailey has not had an easy childhood. Her father, Michael, always too easy with his fists after spending the family’s rent money down the pub. Just sixteen, in love and blinded by promises, Maggie sees marriage to handsome Jack as her great escape. However, she soon finds herself abandoned with a beautiful baby when Jack disappears. Maggie is forced to seek a new life away from the East End of London and finds herself a job at a hotel in Yarmouth.

Bristol 1936. Jenny Crawford has resigned herself to a loveless marriage living hand to mouth with their two children. Like many others, husband Roy struggles to find work at the docks but a chance encounter turns the family's fortunes around. Not only does he get regular work but they are also allocated a council house on Coronation Close on the outskirts of the city. Jenny and the children are overjoyed, this is the fresh start she could only ever dream of. But trouble feels never too far away.

Jane Hadley has nothing to lose when she runs away to join the Women's Auxiliary Air Force. Whatever faces her in war-torn London can't be any worse than staying at home with her abusive father. The city is nothing like she could have imagined, but she's soon on the move, travelling from base to base for her top-secret training. Making plenty of friends along the way, it doesn't take long for Jane to embrace her growing confidence - especially under the attentive eye of dashing Officer Oscar Stanton.

1901. Tina Rose is the beloved daughter of a wealthy Jewish family while Edward grew up with an abusive father in the wilds of New Zealand. Despite their differences, the two fall madly in love when Edward arrives in England, looking for a better future. However, the consequences of their love affair are terrible for Tina, as she is shamed by the father she adores, and Edward is sent away. Against all the odds, Tina and Edward find each other again.

Desperate to escape their stepfather’s house, sisters Amy and Lillian stow away aboard a train full of children being evacuated from London and the threat of Hitler’s bombs. Arriving in the seaside town of Worthing, they are taken in by kindly Norah and her husband, Jim. With their future now entrusted to strangers, can the girls finally find a safe harbour in these dark days of war? And will they find the strength to confront what they have been running from, when their past finally catches up with them?

Rita and Rosie Stevens are only nine and five years old when their widowed mother marries a violent bully called Jimmy Randall and has a baby boy by him. Under pressure from her new husband, she is persuaded to send the girls to an orphanage, not knowing that the papers she has signed will entitle them to do what they like with the children. And it is not long before the powers that be decide to send a consignment of orphans to their sister institution in Australia. Among them - without their family's consent or knowledge - are Rita and Rosie.

At the age of 22, Jennifer Worth left her comfortable home to move into a convent and become a midwife in postwar London’s East End slums. The colorful characters she met while delivering babies all over London - from the plucky, warm-hearted nuns with whom she lived to the woman with 24 children who couldn't speak English to the prostitutes and dockers of the city’s seedier side - illuminate a fascinating time in history.