
So Very Small
How Humans Discovered the Microcosmos, Defeated Germs–and May Still Lose the War Against Infectious Disease
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Narrated by:
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Mike Cooper
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By:
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Thomas Levenson
About this listen
“An elegant, wide-ranging history” (The New York Review of Books) of the centuries-long quest to discover the critical role of germs in disease that reveals as much about human reasoning—and the pitfalls of ego—as it does about microbes.
“Levenson takes readers through an entertaining . . . journey of missed opportunities in microbiology and the eventual advances that arose in this field.”—Science
Scientists and enthusiastic amateurs first confirmed the existence of living things invisible to the human eye in the late seventeenth century. So why did it take two centuries to connect microbes to disease? As late as the Civil War in the 1860s, most soldiers who perished died not on the battlefield but of infected wounds, typhoid, and other diseases. Twenty years later, the outcome might have been different, following one of the most radical intellectual transformations in history: germ theory, the recognition that the tiniest forms of life have been humankind’s greatest killers. It was a discovery centuries in the making, and it transformed modern life and public health.
As Thomas Levenson reveals in this globe-spanning history, it has everything to do with how we see ourselves. For centuries, people in the West, believing themselves to hold God-given dominion over nature, thought too much of humanity and too little of microbes to believe they could take us down. When nineteenth-century scientists finally made the connection, life-saving methods to control infections and contain outbreaks soon followed. The next big break came with the birth of the antibiotic era in the 1930s. And yet, less than a century later, the promise of the antibiotic revolution is already receding due to years of overuse. Is our self-confidence getting the better of us again?
So Very Small follows the thread of human ingenuity and hubris across centuries—along the way peering into microscopes, spelunking down sewers, visiting army hospitals, traipsing across sheep fields, and more—to show how we came to understand the microbial environment and how little we understand ourselves. Levenson traces how and why ideas are pursued, accepted, or ignored—and hence how human habits of mind can, so often, make it terribly hard to ask the right questions.
©2025 Thomas Levenson (P)2025 Random House AudioListeners also enjoyed...
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Critic reviews
“In So Very Small Levenson provides not only the backstory to resistance to variolation but an elegant, wide-ranging history of the discovery of microorganisms and their relation to disease.”—New York Review of Books
“Levenson takes readers through an entertaining, if frustrating, journey of missed opportunities in microbiology and the eventual advances that arose in this field . . . Levenson concludes that ‘we aren’t smarter than the microcosmos,’ and despite centuries of advances, it is clear that he is correct.”—Science
“[So Very Small] offers a compelling story of how microbes have influenced society, seamlessly intertwined with fascinating historical events, while vividly bringing the characters and scientific discoveries to life.”—Alanna Collen, author of 10% Human
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China's Quest for Military Supremacy provides a broad and accessible exploration of Chinese military power, including relations between the Chinese Communist Party and its army, the strategic worldview of Chinese leaders, military strategy and resourcing, conventional and nuclear modernization, military diplomacy and coercion, preparations for war, and the People's Liberation Army's emerging global role.
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Deep Military Analysis
- By Helen C. on 05-19-25
By: Phillip C. Saunders, and others
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A Little Bit of Land
- By: Jessica Gigot
- Narrated by: Julia Whelan
- Length: 5 hrs and 33 mins
- Unabridged
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From midwifing new lambs to harvesting basil, Jessica Gigot invites the listener into her life on a small farm and the uncommon road that led her there. Fascinated by farming and the burgeoning local food movement, she spent her twenties wandering the Pacific Northwest, interning at small farms and doing graduate work in horticulture, always with an eye towards learning as much as she could about how and why people farm.
By: Jessica Gigot
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Turning to Birds
- The Power and Beauty of Noticing
- By: Lili Taylor
- Narrated by: Lili Taylor
- Length: 4 hrs and 16 mins
- Unabridged
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Through a series of beautifully crafted essays, Taylor shares her intimate encounters with the birds that have captured her heart and imagination—from tracking flitting woodpeckers through oak trees to spotting majestic blue jays perched on a Manhattan fire escape; from the exhilaration of witnessing a migratory flock from the top of the Empire State Building to the quiet joy of observing a nest of hatchlings in her own backyard. Through simply paying attention to birds, Lili has been shown a parallel world that is wider and deeper, one of constant change and movement, full of life.
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Bird lovers will rejoice!
- By Fascination with Fear on 05-10-25
By: Lili Taylor
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Proto
- How One Ancient Language Went Global
- By: Laura Spinney
- Narrated by: Emma Spurgin-Hussey
- Length: 9 hrs and 3 mins
- Unabridged
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Daughter. Duhitár-. Dustr. Dukte. Listen to these English, Sanskrit, Armenian and Lithuanian words, all meaning the same thing, and you hear echoes of one of history’s most unlikely journeys. All four languages—along with hundreds of others, from French and Gaelic, to Persian and Polish—trace their origins to an ancient tongue spoken as the last ice age receded. This language, which we call Proto-Indo-European, was born between Europe and Asia and exploded out of its cradle, fragmenting as it spread east and west.
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Brilliant research and narration
- By Dr. Krishnendu Ray on 05-16-25
By: Laura Spinney
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The Great Betrayal
- The Struggle for Freedom and Democracy in the Middle East
- By: Fawaz A. Gerges
- Narrated by: Keval Shah
- Length: 15 hrs and 42 mins
- Unabridged
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The Middle East is in upheaval: a widening chasm between state and society, the failure of governing elites to address citizens' genuine grievances, massive economic mismanagement—all made worse by repeated interventions by Western powers. Why has political change been so difficult to achieve? In The Great Betrayal, Fawaz Gerges argues that the convergence of political authoritarianism, meddling by the West, and the effects of prolonged regional conflicts have produced political paralysis and economic stagnation.
By: Fawaz A. Gerges
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The Year God Died
- Jesus and the Roman Empire in 33 AD
- By: James Lacey
- Narrated by: Mike Cooper
- Length: 7 hrs and 46 mins
- Unabridged
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In late 31 AD, after the Roman senators murdered Lucius Sejanus, the Roman Emperor Tiberius's closest confidant, the Empire was forever changed. If Sejanus had not been murdered, Jesus would never have been crucified. This profound connection between the lives of Sejanus and Jesus is the first of many revelations in this startling reexamination of the Roman world in which Jesus walked. With new evidence and meticulous research, Dr. James Lacey weaves a majestic and accurate description of who Jesus was.
By: James Lacey
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No Country for Old Age
- America's War on Aging from Valley Forge to Silicon Valley
- By: Mischa Honeck
- Narrated by: Al Kessel
- Length: 11 hrs and 5 mins
- Unabridged
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Since the birth of their nation, Americans have acted on the belief that theirs was a land of youth, a place destined to offer a fresh start to an aging world. No Country for Old Age tells this story from the founding period to our present moment, but not without exposing its darker side: rejuvenation has often bred grand expectations that end in division and despair.
By: Mischa Honeck
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The Market in Global International Society
- An English School Approach to International Political Economy
- By: Barry Buzan, Robert Falkner
- Narrated by: Michael Langan
- Length: 15 hrs and 20 mins
- Unabridged
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The Market in Global International Society tracks the idea and practice of the market through both modern and premodern times, and its evolution as a primary institution in international relations over the past two centuries. It develops a new approach to understanding the relationship between the market and other social and political institutions of global international society.
By: Barry Buzan, and others
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The Hunt for Vulcan
- …And How Albert Einstein Destroyed a Planet, Discovered Relativity, and Deciphered the Universe
- By: Thomas Levenson
- Narrated by: Kevin Pariseau
- Length: 5 hrs and 49 mins
- Unabridged
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For more than 50 years, the world's top scientists searched for the "missing" planet Vulcan, whose existence was mandated by Isaac Newton's theories of gravity. Countless hours were spent on the hunt for the elusive orb, and some of the era's most skilled astronomers even claimed to have found it. There was just one problem: It was never there.
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This is great stuff!
- By Mark A. Hurt on 11-22-15
By: Thomas Levenson
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Transcend
- Unlocking Humanity in the Age of AI
- By: Faisal Hoque
- Narrated by: Fajer Al-Kaisi
- Length: 8 hrs and 50 mins
- Unabridged
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In Transcend: Unlocking Humanity in the Age of AI, Faisal Hoque, one of the world’s leading management thinkers and technologists, and a bestselling author, provides listeners with the road maps they need to tackle the most important questions of our generation.
By: Faisal Hoque
Very written and very well performed.
A gripping account of a triumph of humanity, and our limitations
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Loved the historical perspective of so very
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