
Super Agers
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Narrated by:
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Eric Topol
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By:
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Eric Topol
About this listen
Super Agers is a detailed guide to a revolution transforming human longevity. This is a breakthrough moment in the history of human health care. The person making that bold claim is one of the most respected medical researchers in the world, Eric Topol.
Dr. Topol’s unprecedented, evidenced-based guide is about how you and your family and friends can benefit from new treatments coming available at a faster rate than ever. From his unique position as a leader overseeing millions in research funding, Dr. Topol also explains the fundamental reasons—from semaglutides to AI—that we can be confident these breakthroughs will continue. Ninety-five percent of Americans over sixty have at least one chronic disease and almost as many have two. That is the essential problem this revolution is solving. He explains the power of the new approaches to the worst chronic killers—diabetes/obesity, heart disease, cancer, and neurodegeneration—and how treatments can begin long before middle age, and even long after. In thirty years, we will have five times as many people at least one hundred years old and they will be healthier than ever because of the breakthroughs Dr. Topol describes.
The amazing discoveries Topol brings into sharp focus are deeply inspiring about our human potential. We can now realistically see how we can make considerable headway for preventing age-related diseases and may one day be able to slow the body-wide aging process itself.
PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.
©2025 Eric Topol (P)2025 Simon & Schuster AudioListeners also enjoyed...
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Critic reviews
"Super Agers captures the extraordinary potential of today’s biomedical revolution. With breakthroughs like CRISPR genome editing and AI intersecting and accelerating at a remarkable pace, we stand at the threshold of preventing age-related diseases and unlocking new possibilities for longevity. Eric Topol's optimistic and inspiring vision makes this book an essential guide to the future of health."—Jennifer Doudna, Nobel Laureate, CRISPR gene editing co-inventor, and Innovative Genomics Institute founder
"For those looking for simple slogans or short videos to guide them to long life, they will not find it in Dr. Topol's Super Agers! Instead, they will get a detailed, evidence-based and optimistic dose of the truth. The combination of genes, biology, behavior and environment, when subjected to the forces of computation linked to AI, reveal a picture of wondrous complexity of the human condition. The good news is that real progress is being made and that Dr. Topol's gift for expression of complex issues in useful language comes through again."—Robert Califf, former commissioner of the FDA
“Eric Topol is not only a distinguished geneticist, cardiologist, and scientist: he is the most widely read and credible health 'futurist' I know. Super Agers is a highly readable and evidence-based digest of those astonishing advances in medicine, science, and technology that directly affect our lifespans. In its pages is a roadmap for linking your own measurable data with personalized actions and interventions that improve your odds of living longer, and more importantly, doing so in good health. Super Agers is a landmark book."—Abraham Verghese, author of The Covenant of Water
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Story
Until very recently, if you were to ask most doctors, they would tell you there were only two kinds of medicine: the quack kind, and the evidence-based kind. The former is baseless, and the latter based on the best information human effort could buy. Well, Eric Topol isn't most doctors, and he suggests you entertain the notion of a third kind of medicine, one that will make the evidence-based state-of-the-art stuff look scarcely better than an alchemist trying to animate a homunculus in a jar.
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A Rx Prediction for Health Care
- By Lynn on 04-17-12
By: Eric Topol
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SuperAging
- Getting Older Without Getting Old
- By: David Cravit, Larry Wolf
- Narrated by: Jarrod Davis
- Length: 7 hrs and 16 mins
- Unabridged
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Welcome to the dazzling new world of SuperAging, where everything you’ve been taught about aging is challenged. Getting older does not need to mean the end of accomplishment and growth. For SuperAgers, the period after age sixty-five can be one of the most productive and fulfilling times of life. SuperAging is already a reality for millions. But the science, business, and culture of aging have changed at such a rapid pace that they can be hard to keep up with. That’s where authors David Cravit and Larry Wolf can help.
By: David Cravit, and others
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The Exhausted Brain
- The Origin of Our Mental Energy and Why It Dwindles
- By: Michael Nehls MD PhD
- Narrated by: David Aranovich
- Length: 10 hrs and 56 mins
- Unabridged
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Everyone knows the feeling after a long day—it is difficult to concentrate, make good decisions, or even empathize with others. This daily but completely natural decline in our mental capacity is called “ego depletion,” a state of mind that miraculously but naturally disappears after a good night's sleep. However, more and more people are waking up in a perpetual state of ego depletion: their mental energy source is not recharging—it is actually shrinking. We live in a chronically exhausted society with disastrous consequences for ourselves, society, and future generations.
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Outlive
- The Science and Art of Longevity
- By: Peter Attia MD, Bill Gifford - contributor
- Narrated by: Peter Attia MD
- Length: 17 hrs and 7 mins
- Unabridged
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Wouldn’t you like to live longer? And better? In this operating manual for longevity, Dr. Peter Attia draws on the latest science to deliver innovative nutritional interventions, techniques for optimizing exercise and sleep, and tools for addressing emotional and mental health.
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Too Much Filler
- By J. Badaracco on 04-09-23
By: Peter Attia MD, and others
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How Things Are Made
- A Journey Through the Hidden World of Manufacturing
- By: Tim Minshall
- Narrated by: Tim Minshall
- Length: 8 hrs and 17 mins
- Unabridged
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Brimming with energy and lively examples, How Things Are Made maps the awe-inspiring global system of manufacturing that enables virtually every aspect of our existence. By making sense of this surprising and hidden world, we are able to make better choices for ourselves, our communities, and the planet.
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Engrossing and Informative
- By Katherine Barton on 05-24-25
By: Tim Minshall
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Ageless
- The New Science of Getting Older Without Getting Old
- By: Andrew Steele
- Narrated by: Andrew Steele
- Length: 9 hrs and 47 mins
- Unabridged
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Aging - not cancer, not heart disease - is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: There are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are.
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General overview of aging and aging research
- By RealWoman8 on 03-31-21
By: Andrew Steele
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Embrace Discomfort
- Lean Into Challenge to Improve Your Life
- By: Michael Easter
- Narrated by: Michael Easter
- Length: 4 hrs and 31 mins
- Original Recording
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In Embrace Discomfort, Michael Easter seeks out off-the-grid visionaries, disruptive genius researchers, and mind-body conditioning trailblazers who are unlocking the life-enhancing secrets of a counterintuitive solution: discomfort. Each of the 10 episodes except for the final one will feature an expert in a discomfort area, including ultra-runner Courtney Dauwalter, survivalist Laura Zerra, nutritionist Dr. Trevor Kashey, and fear expert Dr. Joseph E. LeDoux
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Would love this as a recurring series!
- By LME on 04-28-25
By: Michael Easter
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Diet, Drugs, and Dopamine
- The New Science of Achieving a Healthy Weight
- By: David A. Kessler M.D.
- Narrated by: Hillary Huber, David A. Kessler M.D.
- Length: 11 hrs and 57 mins
- Unabridged
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From the New York Times bestselling author of The End of Overeating comes an illuminating understanding of body weight, including the role of the latest weight loss drugs, and the possibility of changing our health, weight, and bodies forever.
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Hold Plant Based
- By Bert Garcia on 05-21-25
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The Great Nerve
- The New Science of the Vagus Nerve and How to Harness Its Healing Reflexes
- By: Kevin J. Tracey MD
- Narrated by: Mark Deakins
- Length: 8 hrs
- Unabridged
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By opening the door to the new field of neuroimmunology, The Great Nerve not only revolutionizes how we understand and treat disease, it gives us unprecedented hope for our health. This is the story of your body’s ability to heal itself.
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This book is an advertisement for the author's medical devices
- By Kirsten K. on 05-24-25
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The Longevity Leap
- A Guide to Slowing Down Biological Aging and Adding Healthy Years to Your Life
- By: Siim Land
- Narrated by: ALIO Voices
- Length: 25 hrs and 28 mins
- Unabridged
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Aging and longevity are something humans have been thinking about throughout our history. Life expectancies worldwide are increasing and people are living longer than ever before. This raises the question, how do you maintain a higher quality of life even when living longer? Furthermore, how long could you live if you were to follow all the latest science about longevity and slowing down aging?
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Science-backed. Actionable. Will reread.
- By Inka Land, MSc on 05-02-25
By: Siim Land
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So Very Small
- How Humans Discovered the Microcosmos, Defeated Germs–and May Still Lose the War Against Infectious Disease
- By: Thomas Levenson
- Narrated by: Mike Cooper
- Length: 10 hrs and 11 mins
- Unabridged
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“An elegant, wide-ranging history” (The New York Review of Books) of the centuries-long quest to discover the critical role of germs in disease that reveals as much about human reasoning—and the pitfalls of ego—as it does about microbes.
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A gripping account of a triumph of humanity, and our limitations
- By Something Innocuous on 05-12-25
By: Thomas Levenson
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Aging Well
- Surprising Guideposts to a Happier Life from the Landmark Study of Adult Development
- By: George E. Vaillant MD
- Narrated by: Keith Sellon-Wright
- Length: 12 hrs and 22 mins
- Unabridged
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Harvard Medical School has followed 824 subjects - men and women, some rich, some poor - from their teens to old age. Harvard's George Vaillant now uses these studies - the most complete ever done anywhere in the world - and the subjects' individual histories to illustrate the factors involved in reaching a happy, healthy old age. He explains precisely why some people turn out to be more resilient than others, the complicated effects of marriage and divorce, negative personality changes, and how to live a more fulfilling, satisfying and rewarding life in the later years.
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Both too detailed and too simple
- By Joseph on 07-14-24
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Walk Yourself Well
- Step into a Healthier, Happier You
- By: Nina Barough
- Narrated by: Nina Barough
- Length: 5 hrs and 35 mins
- Unabridged
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In Walk Yourself Well, walking expert Nina Barough will teach you how to make the most out of every step–from mastering your technique and setting your pace to walking in different climates and terrains. Go that extra mile, and get inspired, with Nina’s motivational training programs, research backed tips to get the most out of every step, plus inspirational walks from around the world for every level.
By: Nina Barough
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Undeniable
- How to Reach the Top and Stay There
- By: Cameron Hanes
- Narrated by: Andrew D. Huberman Ph.D., Cameron Hanes
- Length: 8 hrs and 17 mins
- Unabridged
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You become the best you can be by learning from others. That is how bowhunter and ultramarathoner Cameron Hanes approaches each day in his pursuit of greatness in this essential guide to finding success.
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an embarrassment
- By Cynthia Callison on 05-10-25
By: Cameron Hanes
The book brims with valuable, up-to-the-minute insights, yet prospective readers should be forewarned: Super Agers is no breezy popular science title. Large sections read more like rigorous academic reviews than general-interest prose. Topol marshals hundreds of studies and showers the reader with specialized terminology, technical data, and acronyms, many of which would likely bewilder even the most diligent, college-educated audience. Skimming, rather than savoring, may become a survival strategy for many readers.
Given Topol’s professional roots, it is no surprise that his discussion of cardiovascular disease prevention is among the book’s strongest and clearest contributions. By contrast, the opening to Chapter 6, which addresses cancer, is strikingly disjointed—an odd lapse in an otherwise meticulously constructed narrative.
Among the most revelatory sections is Topol’s exploration of GLP-1 receptor agonists, a class of drugs already famous for their role in diabetes and obesity treatment. Topol convincingly argues that their potential impact extends much further, suggesting they may reshape the landscape of medicine itself. “The impact of GLP-1 drugs in medicine—for improving patient outcomes—will likely be more substantial than any prior class of medications,” he writes, noting their “major triumph” in combining high efficacy with favorable safety profiles. At one point, Topol even speculates that “it is conceivable that most people will be taking one of the GLP-1 drugs in the future.” It’s a bold assertion, but one he supports with considerable evidence.
Topol’s scholarly rigor is reinforced by an exhaustive list of references, although the unconventional note system—linking citations to chapter and page numbers rather than traditional footnotes—and the minuscule font size used for these notes are sure to frustrate anyone wishing to dive deeper without a magnifying glass.
The ultimate question, then, is: for whom was this book written? Despite its glossy cover and broad promises, Super Agers seems best suited to practicing physicians, researchers, and highly motivated lay readers with a tolerance for complexity. Those willing to persevere will be rewarded with a bracing, if at times arduous, journey through the cutting edge of preventive medicine.
Super Agers may not offer an easy path to a longer life, but it is a serious guide for those determined to understand—and perhaps seize—the promise of modern longevity science.
A Dense but Illuminating Map to Longer, Healthier Lives
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Title not indicative of content
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Nothing New, Move Along
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Old outdated studies … don’t bother to listen
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Brilliant work highlighting the advances of geroscience
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I am not sure why, but none of the platforms where I am able to read this book offer any instruction about how to download the PDF file that Dr. Topol is constantly referring to. I will keep trying to find it because it sounds interesting.
About survival
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