After a difficult five years, at age forty-three, Nina Morgan Clarke’s time has finally arrived. With an ex-husband relocated across the country, her father bouncing back after the loss of his beloved wife, and her daughter, Xandra, thriving at boarding school, Nina is stepping into her dream job as a trifecta: a first-generation, Black female head of the storied Royal-Hawkins School. To mark the moment, Nina and her best friend, Marisol, take a long-overdue girls’ trip to celebrate the second half of Nina’s life—which is shaping up to be the best part of her life.

In the spring of 2020, Lara’s three daughters return to the family's orchard in Northern Michigan. While picking cherries, they beg their mother to tell them the story of Peter Duke, a famous actor with whom she shared both a stage and a romance years before at a theater company called Tom Lake. As Lara recalls the past, her daughters examine their own lives and relationship with their mother, and are forced to reconsider the world and everything they thought they knew.

It’s June 2012. The magical and slightly cultish River Run swim club is alive with the spirit of fun competition when a perfect storm brews between team moms and best friends Gillian Cloud and Kristy Weinstein. The ghost of family addiction has turned up, looming over their carefully planned pasta parties, tie-dye nights, and pep rallies, forcing them to face their unresolved childhood trauma. Gillian responds by trying to control everyone around her while Kristy relapses into her dangerous addiction to love.

High-powered businesswoman Lana Rubicon has a lot to be proud of: her keen intelligence, impeccable taste, and the L.A. real estate empire she’s built. But when she finds herself trapped 300 miles north of the city, convalescing in a sleepy coastal town with her adult daughter Beth and teenage granddaughter Jack, Lana is stuck counting otters instead of square footage—and hoping that boredom won’t kill her before the cancer does.

Celebrating her forty-fifth birthday at her local pub, popular podcaster Alix Summer crosses paths with an unassuming woman called Josie Fair. Josie, it turns out, is also celebrating her forty-fifth birthday. They are, in fact, birthday twins. A few days later, Alix and Josie bump into each other again, this time outside Alix’s children’s school. Josie has been listening to Alix’s podcasts and thinks she might be an interesting subject for her series. She is, she tells Alix, on the cusp of great changes in her life.

Sadie Montgomery never saw what was coming . . . Literally! One minute she’s celebrating the biggest achievement of her life—placing as a finalist in the North American Portrait Society competition—the next she’s lying in a hospital bed diagnosed with a “probably temporary” condition known as face blindness. She can see, but every face she looks at is now a jumbled puzzle of disconnected features. Imagine trying to read a book upside down and in another language. This is Sadie’s new reality.

Authors June Hayward and Athena Liu were supposed to be twin rising stars: same year at Yale, same debut year in publishing. But Athena’s a cross-genre literary darling, and June didn’t even get a paperback release. Nobody wants stories about basic white girls, June thinks. So when June witnesses Athena’s death in a freak accident, she acts on impulse: she steals Athena’s just-finished masterpiece, an experimental novel about the unsung contributions of Chinese laborers to the British and French war efforts during World War I.

Sasha has had it. She cannot bring herself to respond to another inane, “urgent” email or participate in the corporate employee joyfulness program. She hasn’t seen her friends in months. Sex? Seems like a lot of effort. Even cooking dinner takes far too much planning. Sasha has hit a wall. Armed with good intentions to drink kale smoothies, try yoga, and find peace, she heads to the seaside resort she loved as a child. But it’s the off season, the hotel is in a dilapidated shambles, and she has to share the beach with the only other occupant: a grumpy guy named Finn.

Hollis Shaw, creator of the popular food blog, Hungry with Hollis, is shocked when her heart surgeon husband, Matthew, is killed in a one-car accident on a snowy morning. The cracks in Hollis’s perfect life—her strained marriage and her complicated relationship with her daughter, Caroline—grow deeper. So when Hollis hears about something called a “Five-Star Weekend”—one woman organizes a trip for her best friend from each phase of her life: her teenage years, her twenties, her thirties, and midlife—she decides to host her own Five-Star Weekend on Nantucket.

Vera Wong is a lonely little old lady—ah, lady of a certain age—who lives above her forgotten tea shop in the middle of San Francisco’s Chinatown. Despite living alone, Vera is not needy, oh no. She likes nothing more than sipping on a good cup of Wulong and doing some healthy detective work on the Internet about what her Gen-Z son is up to. Then one morning, Vera trudges downstairs to find a curious thing—a dead man in the middle of her tea shop.

Mia, the irreverent, hyperanalytical twenty-year-old daughter, has an explanation for everything—which is why she isn’t initially concerned when her father and younger brother Eugene don’t return from a walk in a nearby park. They must have lost their phone. Or stopped for an errand somewhere. But by the time Mia’s brother runs through the front door bloody and alone, it becomes clear that the father in this tight-knit family is missing and the only witness is Eugene, who has the rare genetic condition Angelman syndrome and cannot speak.

According to Confucius, “an educated woman is a worthless woman,” but Tan Yunxian—born into an elite family, yet haunted by death, separations, and loneliness—is being raised by her grandparents to be of use. Her grandmother is one of only a handful of female doctors in China, and she teaches Yunxian the pillars of Chinese medicine, the Four Examinations—looking, listening, touching, and asking—something a man can never do with a female patient.

Jen Weinstein and Lauren Parker rule the town of Salcombe, Fire Island every summer. They hold sway on the beach and the tennis court, and are adept at manipulating people to get what they want. Their husbands, Sam and Jason, have summered together on the island since childhood, despite lifelong grudges and numerous secrets. Their one single friend, Rachel Woolf, is looking to meet her match, whether he’s the tennis pro. But even with plenty to gossip about, this season starts out as quietly as any other. Until a body is discovered, face down, off the side of the boardwalk.

Sergeant Vila Kiprik has survived many brutal missions during his 30-year army career, but this last posting to Demon's Deep is his deadliest yet. Top brass need the mine working again for its rare quartz deposits, but the miners have gone AWOL, replaced by crazed savages. Kiprik and his squad have been charged with taking back control, but this is no ordinary drive. Sinister forces more deadly than madmen hunt them in the shadows, and that retirement up in the Duchy mountains soon begins to look like a pipe dream.

It’s been a minute—or five years—since Jordan Vargas last saw his college friends, and twenty-eight years since their graduation from Berkeley when their adult lives officially began. Now Jordan, Jordy, Naomi, Craig, and Marielle find themselves at the brink of a new decade, with all the responsibilities of adulthood, yet no closer to having their lives figured out. Though not for a lack of trying. Over the years they’ve reunited in Big Sur to honor a decades-old pact to throw each other living “funerals,” celebrations to remind themselves that life is worth living.