A two thousand year old secret leads Sherlock Holmes and Doctor Watson along a dark & death laden path to the lair of a ruthless master criminal. Even Holmes cannot foresee the final outcome.

Holmes and Watson are handed the challenge of solving the London Tarot Murders, a dark episode which, to quote Dr. Watson's in his memoirs, "occupies a lofty place in the annals of all black deeds ever committed in the long memory of the ancient, regal city, higher even than the infamous affair with the Ripper."

When Mrs. Hudson asks Holmes and Watson to find a missing girl, neither men expected what they would find. Along with Lestrade, they are plunged into a case of abduction and murder. As they race from Marylebone, to Finchley, to Wapping, and back again, time is running out for them to solve the case without further casualties. With two of their own under threat, the pressure is mounting to catch and stop the group known as "Hellfire Heirs".

In The Sign of Four, the great detective, Sherlock Holmes, famously says: "... when you have eliminated the impossible, whatever remains, however improbable, must be the truth ...". Eliminate the Impossible collects six canonical tales in which Holmes and Watson encounter mummies, angels, phantoms, invisible assassins, and arcane machines ... or so it might appear to those without a carefully stocked brain attic.

Holmes and Watson were supposed to be on vacation of sorts amongst the Cornish greenery and archaeological treasures, since it had become clear enough that the pressure of the detective’s investigations had taken a toll on his nerves, and a few days away from London in the country was prescribed. But their excursion was rudely interrupted when murders most heinous came to light. The so-called Devils’ Foot was a deadly substance of unknown origin that kills when inhaled.