The Code Breaker
Jennifer Doudna, Gene Editing, and the Future of the Human Race
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Narrated by:
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Kathe Mazur
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By:
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Walter Isaacson
About this listen
The best-selling author of Leonardo da Vinci and Steve Jobs returns with a gripping account of how the pioneering scientist Jennifer Doudna, along with her colleagues and rivals, launched a revolution that will allow us to cure diseases, fend off viruses, and enhance our children.
An Audie Award 2022 Finalist
In the spring of 2012, the Berkeley biochemist Jennifer Doudna and her collaborators turned a curiosity of nature into an invention that will transform the future of the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. It has already been deployed to cure deadly diseases, fight the coronavirus pandemic of 2020, and make inheritable changes in the genes of babies.
The development of CRISPR and the war against coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been an information-technology era, based on the microchip, the computer, and the internet. Now we are entering an even more momentous era, a life-science revolution. Children who study digital coding will be surpassed by those who study the code of life.
Should we use our new evolution-hacking powers to make us less susceptible to viruses and eliminate dreaded disorders? What a wonderful boon that would be! Right? And what about preventing congenital deafness or blindness? Or being very short? Or being depressed? Hmmm....how should we think about that? Should we allow parents, if they can afford it, to enhance the IQ or height or memory or muscles of their kids?
After helping to discover CRISPR, Doudna became a leader in wrestling with these moral and policy issues. Her life story illustrates that the key to innovation is connecting basic science to our everyday lives - moving discoveries from our labs to our bedsides - in ways that respect our moral values. It’s a thrilling detective tale that involves the most profound wonders of nature, from the origins of life to the future of our species.
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Headstrong
- 52 Women Who Changed Science-and the World
- By: Rachel Swaby
- Narrated by: Lauren Fortgang
- Length: 7 hrs and 1 min
- Unabridged
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In 2013, the New York Times published an obituary for Yvonne Brill. It began: “She made a mean beef stroganoff, followed her husband from job to job, and took eight years off from work to raise three children.” It wasn’t until the second paragraph that readers discovered why the Times had devoted several hundred words to her life: Brill was a brilliant rocket scientist who invented a propulsion system to keep communications satellites in orbit, and had recently been awarded the National Medal of Technology and Innovation.
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Role models for young women
- By mtsuda90 on 06-25-16
By: Rachel Swaby
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A Crack in Creation
- Gene Editing and the Unthinkable Power to Control Evolution
- By: Jennifer A. Doudna, Samuel H. Sternberg
- Narrated by: Erin Bennett
- Length: 9 hrs and 22 mins
- Unabridged
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Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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In to the abyss we ascend, a scary future
- By Philomath on 06-17-17
By: Jennifer A. Doudna, and others
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The Exceptions
- Nancy Hopkins, MIT, and the Fight for Women in Science
- By: Kate Zernike
- Narrated by: Kathe Mazur
- Length: 14 hrs and 31 mins
- Unabridged
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In 1963, a female student was attending a lecture given by Nobel Prize winner James Watson, then tenured at Harvard. At nineteen, she was struggling to define her future. She had given herself just ten years to fulfill her professional ambitions before starting the family she was expected to have. For women at that time, a future on the usual path of academic science was unimaginable—but during that lecture, young Nancy Hopkins fell in love with the promise of genetics. Confidently believing science to be a pure meritocracy, she embarked on a career.
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Unbelievable and deeply inspiring.
- By Lilit Garibyan on 06-05-23
By: Kate Zernike
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Tomorrowland
- Our Journey From Science Fiction to Science Fact
- By: Steven Kotler
- Narrated by: Tom Parks
- Length: 8 hrs and 58 mins
- Unabridged
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New York Times, Wired, Atlantic Monthly, Discover bestselling author Steven Kotler has written extensively about those pivotal moments when science fiction became science fact...and fundamentally reshaped the world. Now he gathers the best of his best, updated and expanded upon, to guide listeners on a mind-bending tour of the far frontier, and how these advances are radically transforming our lives.
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Covers a lot of different topics in many industries
- By ErnieA on 06-27-15
By: Steven Kotler
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Neanderthal Man
- In Search of Lost Genomes
- By: Svante Pääbo
- Narrated by: Dennis Holland
- Length: 10 hrs and 36 mins
- Unabridged
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A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.
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Excellent science tale
- By Neuron on 01-19-15
By: Svante Pääbo
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101 Theory Drive
- A Neuroscientist's Quest for Memory
- By: Terry McDermott
- Narrated by: Stephen Hoye
- Length: 8 hrs and 55 mins
- Unabridged
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It's not fiction: Gary Lynch is the real thing, the epitome of the rebel scientist - malnourished, contentious, inspiring, explosive, remarkably ambitious, consistently brilliant. He is one of the foremost figures of contemporary neuroscience, and his decades-long quest to understand the inner workings of the brain's memory machine has begun to pay off.
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Pretty Dang Funny
- By Will on 05-14-10
By: Terry McDermott
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Whiplash
- How to Survive Our Faster Future
- By: Joi Ito, Jeff Howe
- Narrated by: James Foster
- Length: 7 hrs and 48 mins
- Unabridged
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Today, not only is everything digital getting faster, cheaper, and smaller at an exponential rate, we also have the Internet. When these two revolutions - one in technology and the other in communications - joined, an explosive force was unleashed that changed the very nature of innovation. And with any change, we have seen many strategic blunders and extraordinary learning curves along the way.
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Just general advice on how to survive
- By A. Yoshida on 09-01-17
By: Joi Ito, and others
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The Problem of Alzheimer's
- How Science, Culture, and Politics Turned a Rare Disease into a Crisis and What We Can Do About It
- By: Jason Karlawish
- Narrated by: Jason Karlawish, Jonathan Todd Ross
- Length: 13 hrs and 41 mins
- Unabridged
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In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.
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A must read
- By kara kuntz on 05-20-21
By: Jason Karlawish
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The Gene
- An Intimate History
- By: Siddhartha Mukherjee
- Narrated by: Dennis Boutsikaris
- Length: 19 hrs and 22 mins
- Unabridged
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The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.
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It's a Wonderful Book
- By JKC on 06-02-16
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Thinking Machines
- The Quest for Artificial Intelligence - and Where It's Taking Us Next
- By: Luke Dormehl
- Narrated by: Gus Brown
- Length: 8 hrs and 12 mins
- Unabridged
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When most of us think about artificial intelligence, our minds go straight to cyborgs, robots, and sci-fi thrillers where machines take over the world. But the truth is that artificial intelligence is already among us. It exists in our smartphones, fitness trackers, and refrigerators that tell us when the milk will expire. In some ways the future people dreamed of at the World's Fair in the 1960s is already here. We're teaching our machines how to think like humans, and they're learning at an incredible rate.
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Mostly platitudes with no depth
- By Gary on 03-24-17
By: Luke Dormehl
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The Chaos Imperative
- How Chance and Disruption Increase Innovation, Effectiveness, and Success
- By: Ori Brafman, Judah Pollack
- Narrated by: Drew Birdseye
- Length: 4 hrs and 28 mins
- Unabridged
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Ori Brafman and management consultant Judah Pollack dramatically demonstrate how even the best and most efficient organizations - from Fortune 500 companies to today's US Army - can become more innovative by allowing a little unstructured space and "contained chaos" into their planning and decision-making. Through their consulting work, they realized that while structure and hierarchy are essential both in large corporations and small groups, too much of either can stifle creativity.
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a must read!!
- By Kelly Pavich on 05-26-19
By: Ori Brafman, and others
What listeners say about The Code Breaker
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Mark T Ryan
- 10-14-23
RNA explained
More than a history lesson, a story that should be universally understood by as many people as possible.
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