The Gene
An Intimate History
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Narrated by:
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Dennis Boutsikaris
About this listen
From the Pulitzer Prize-winning, best-selling author of The Emperor of All Maladies, a magnificent history of the gene and a response to the defining question of the future: What becomes of being human when we learn to "read" and "write" our own genetic information?
2017 Audie Award Finalist for Non-Fiction
The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.
Throughout the narrative, the story of Mukherjee's own family - with its tragic and bewildering history of mental illness - cuts like a bright red line, reminding us of the many questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In superb prose and with an instinct for the dramatic scene, he describes the centuries of research and experimentation - from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Thomas Morgan to Crick, Watson, and Rosa Franklin, all the way through the revolutionary 21st-century innovators who mapped the human genome.
As The New Yorker said of The Emperor of All Maladies, "It's hard to think of many books for a general audience that have rendered any area of modern science and technology with such intelligence, accessibility, and compassion.... An extraordinary achievement."
A riveting, revelatory, and magisterial history of a scientific idea coming to life and an essential preparation for the moral complexity introduced by our ability to create or "write" the human genome, The Gene is a must-listen for everyone concerned about the definition and future of humanity. This is the most crucial science of our time, intimately explained by a master.
Download the accompanying reference guide.©2016 Siddhartha Mukherjee, M.D. All rights reserved. (P)2016 Simon & Schuster, Inc. All rights reserved.Listeners also enjoyed...
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Featured Article: The Best Science Listens to Channel Your Inner Einstein
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What is life? Humans have been asking this question for thousands of years. But as technology has advanced and our understanding of biology has deepened, the answer has evolved. For decades, scientists have been exploring the limits of nature by modifying and manipulating DNA, cells, and whole organisms to create new ones that could never have previously existed on their own.
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The Goldilocks book on what is life
- By Gary on 07-11-13
By: Adam Rutherford
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The Cancer Chronicles
- Unlocking Medicine's Deepest Mystery
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- Narrated by: Arthur Morey
- Length: 8 hrs and 19 mins
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When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.
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A quick read - hard to put down
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By: George Johnson
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How to Build a Dinosaur
- Extinction Doesn't Have to Be Forever
- By: Jack Horner, James Gorman
- Narrated by: Patrick Lawlor
- Length: 6 hrs and 36 mins
- Unabridged
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In movies, in novels, in comic strips, and on television, we've all seen dinosaurs - or at least somebody's educated guess of what they would look like. But what if it were possible to build, or grow, a real dinosaur without finding ancient DNA? Jack Horner, the scientist who advised Steven Spielberg on the blockbuster film Jurassic Park and a pioneer in bringing paleontology into the 21st century, teams up with the editor of the New York Times's Science Times section to reveal exactly what's in store.
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Good book but misplaced title
- By Robert on 06-19-15
By: Jack Horner, and others
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Herding Hemingway's Cats
- Understanding How Our Genes Work
- By: Kat Arney
- Narrated by: Kat Arney
- Length: 8 hrs and 39 mins
- Unabridged
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The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work?
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A non-scientists misguided interpretation
- By AraSevera on 05-15-16
By: Kat Arney
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The Language of Life
- DNA and the Revolution in Personalized Medicine
- By: Francis S. Collins
- Narrated by: Greg Itzin
- Length: 10 hrs and 45 mins
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A scientific and medical revolution has crept up on us, based on study after study, from hundreds of laboratories around the world. It is no longer just a theoretical shift: every one of us will be touched by it, and many of us already have been. The meaning of disease, our understanding of the human body, and crucial decisions about what we all need to know and what choices we make about our health are at stake. Welcome to the new world of personalized medicine.
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The future of medicine
- By Ronald E on 04-12-10
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Neanderthal Man
- In Search of Lost Genomes
- By: Svante Pääbo
- Narrated by: Dennis Holland
- Length: 10 hrs and 36 mins
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A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.
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Excellent science tale
- By Neuron on 01-19-15
By: Svante Pääbo
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Life Unfolding
- How the Human Body Creates Itself
- By: Jamie A. Davies
- Narrated by: Napoleon Ryan
- Length: 9 hrs and 56 mins
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Where did I come from? Why do I have two arms but just one head? How is my left leg the same size as my right one? Why are the fingerprints of identical twins not identical? How did my brain learn to learn? Why must I die? Questions like these remain biology's deepest and most ancient challenges. They force us to confront a fundamental biological problem: How can something as large and complex as a human body organize itself from the simplicity of a fertilized egg?
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Fascinating Biology ; Distracting Narration
- By Tim on 03-01-15
By: Jamie A. Davies
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Editing Humanity
- The CRISPR Revolution and the New Era of Genome Editing
- By: Kevin Davies
- Narrated by: Kevin Davies
- Length: 16 hrs and 17 mins
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Engrossing and captivating, Editing Humanity takes listeners inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces listeners to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.
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Excellent content, solid execution
- By Samuel Finlayson on 01-25-21
By: Kevin Davies
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Welcome to the Microbiome
- Getting to Know the Trillions of Bacteria and Other Microbes In, On, and Around You
- By: Rob DeSalle, Susan L. Perkins
- Narrated by: Stephen McLaughlin
- Length: 7 hrs and 25 mins
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Suddenly, research findings require a paradigm shift in our view of the microbial world. The Human Microbiome Project at the National Institutes of Health is well under way, and unprecedented scientific technology now allows the censusing of trillions of microbes inside and on our bodies as well as in the places where we live, work, and play. This intriguing, up-to-the-minute book for scientists and nonscientists alike explains what researchers are discovering about the microbe world and what the implications are for modern science and medicine.
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I learned so much from this book. I am happy.
- By Jonathan Miller on 09-08-18
By: Rob DeSalle, and others
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An Epidemic of Absence
- A New Way of Understanding Allergies and Autoimmune Diseases
- By: Moises Velasquez-Manoff
- Narrated by: Chris Sorensen
- Length: 17 hrs and 6 mins
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An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
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The point of view from a Veterinarian immunologist
- By rtgymnast on 11-03-17
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Vagina Obscura
- An Anatomical Voyage
- By: Rachel E. Gross
- Narrated by: Siho Ellsmore
- Length: 10 hrs and 50 mins
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The Latin term for the female genitalia, pudendum, means “parts for which you should be ashamed”. Until 1651, ovaries were called female testicles. The fallopian tubes are named for a man. Named, claimed, and shamed: Welcome to the story of the female body, as penned by men. Today, a new generation of (mostly) women scientists is finally redrawing the map. With modern tools and fresh perspectives, they’re looking at the organs traditionally bound up in reproduction—the uterus, ovaries, vagina—and seeing within them a new biology of change and resilience.
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poor narration
- By Jane on 08-23-22
By: Rachel E. Gross
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The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.
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Except for the author, this book is good!
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An Elegant Defense
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A magnificently reported and soulfully crafted exploration of the human immune system - the key to health and wellness, life and death. An epic, first-of-its-kind audiobook, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize-winning New York Times journalist.
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Weak foundation, good conclusion
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What listeners say about The Gene
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Buce
- 06-13-16
Splendid, but you also need the print.
Any additional comments?
This is a splendid book, superbly read--better than his excellent history of cancer--with only one reservation. That is: it is too compact to be absorbed in audio only. I started off without text and changed my mind about a third of the way in. I absorbed much more once I downloaded the Kindle although it is rich enough---and good enough--that it would easily reward a second read/listen. Highest marks for the audio but also get the Kindle (or paper).
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29 people found this helpful
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- axel hinsch
- 05-30-16
Recommended reading !!!
Grrat review of the history of the discovery of hereditary traits, DNA, genes, the moral implications of the past, present and future. Loved it.
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3 people found this helpful
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Overall
- Joan Pont
- 06-02-16
superb
long.. wonderful and beautifully read. little did I know how little I knew.
Allan Pont md
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3 people found this helpful
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- thomas j wagar
- 08-23-18
fascinating detail and information
well worth the read. Really makes you think and wonder about the future. highly recommended
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- Soushiant Zanganehpour
- 09-17-17
More descriptive than prescriptive
80-90% of the book is a detailed historical review of all the theoretical revelations, experiments and building blocks that have lead us to where we are today; with the ability to alter genes. I wish more time was spent discussing and analyzing the implications of where we are today, providing some normative and practical boundaries of how we might move forward.
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- Girona
- 10-10-18
Step by step guided through the modern biology
Nice review of the history of modern biology, even knowing most of the facts told in this book it's organization and narrative is exceptional.
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- Renee
- 10-10-17
Packed with information!
Dense with interesting information. The conclusions and closing thoughts give us, as a species, much to think about.
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- Kip
- 03-07-17
Good mix of technical and laymans information
Murkagee does a great job blending a personal story with the history of genetic evolution and discovery. The latter half gets more technical and interestingly dives into moral arguments over the limits of what we can or should do with genetic experimentation. Fantastic performance.
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- S. Chapin
- 06-13-16
Why we are so much different yet so much alike
This book was wonderful and should be on everyone's MUST read list. Genetics are the reason we have homosexuals and heterosexuals, obese, and many syndromes, cancers, and diseases. Like everything else is life, there is the good, bad and ugly.
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- Alreadythoughtofit
- 08-16-17
Outstanding
One of those gems that makes complicated concepts accessible to the interested ordinary person. At the same time, it is not for the ignorant.
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