A string of overdoses in Colorado Springs has Detectives Joe Kenda and Lee Wilson on the lookout for a bad batch of heroin that has been cut with a drug they’ve never seen before. Meanwhile, at Springs General Hospital, Dr. Blair Moreland—the notoriously unpleasant head anesthesiologist—has found a way to feed his deepening addiction to the very same powerful new drug: fentanyl. But when Dr. Moreland starts supplying the dangerous painkiller to dealer Lula Lopez, he angers a Mexican crime syndicate and sets into motion a cycle of death and violence that threatens to engulf the entire city.

In 1994, an aspiring young cold-case investigator in California’s East Bay, Paul Holes, puts aside trying to solve the Golden State Killer case as he waits for science to catch up. Paul returns to an old file cabinet at the back of the forensic lab to look for another cold case he can work—something with DNA. He finds one. The 1978 murder of a married mother who went for a morning jog in a nearby park. The original investigators believed that a serial killer named Phillip Hughes was responsible; they just couldn’t prove it.

In the summer of 1995, at the largest Boy Scout camp in Ohio, a night of sexual violence ended with one counselor dead and another hospitalized. The death was ruled "accidental." It wouldn't be the last death associated with Seven Ranges Reservation. James Renner, too, was a counselor at Seven Ranges that year. He was always sure there must be more to the story of Mike Klingler's death, because Renner also knew firsthand that the 900-acre camp was not the safe getaway it was portrayed to be.

Elmer Wayne Henley, Jr. was only fourteen when he first became entangled with serial rapist and murderer Dean Corll in 1971. Fellow Houston, Texas, teenager David Brooks had already been ensnared by the charming older man, bribed with cash to help lure boys to Corll's home. Corll baited Henley with the same deal he'd given Brooks: $200 for each boy they could bring him.

Rich Cohen’s Murder in the Dollhouse is the chilling story of Jennifer Dulos, a beautiful, rich suburban mother who dropped her kids off at the New Canaan Country School one morning and vanished. Her body has never been found. Dulos was in the midst of an ugly divorce—one of the most contentious in Connecticut state history. The couple, a beautiful, highly connected pair, met at Brown University, had five children, and led what appeared to be a charmed life. In the wake of her disappearance, Dulos’s husband and his girlfriend were arrested.

Lurking beneath the progressive activism and sex positivity in the 1970 to '80s, a dark undercurrent of violence rippled across the American landscape. With reported cases of sexual assault and homicide on the rise, the FBI created a specialized team - the “Mindhunters”, better known as the Behavioral Science Unit - to track down the country's most dangerous criminals. And yet narrowing down a seemingly infinite list of potential suspects seemed daunting at best and impossible at worst - until Dr. Ann Wolbert Burgess stepped on the scene.

Melissa Ramirez, Claudine Anne Luera, Guiselda Hernandez, and Janelle Ortiz were four marginalized women striving to make ends meet as sex workers. They looked out for one another. But they would soon share a connection that none of them could have imagined. When Melissa was found dead, the other three women were on edge but assumed they were safe. Twelve days later, they too were dead and police had detained an unlikely suspect—Juan David Ortiz, a ten-year veteran of the U.S. Customs and Border Protection.

Fans of true crime shows like CSI, NCIS, Criminal Minds, and Law and Order know that when it comes to “getting the bad guy” behind bars, your best chance of success boils down to the strength of your evidence—and the forensic science used to obtain it. Beyond the silver screen, forensic science has been used for decades to help solve even the most tough-to-crack cases.

John Douglas once again takes us fascinatingly behind the scenes, focusing his expertise on predatory crimes, primarily against women. With a deep sense of compassion for the victims and an uncanny understanding of the perpetrators, Douglas looks at the obsessions that lead to rape, stalking, and sexual murder through such cases as Ronnie Shelton, the serial rapist who terrorized Cleveland; and New York's notorious "Preppie Murder". But Douglas also looks at obsession on the other side of the moral spectrum: his own career-long obsession with hunting these predators.

Rookie Det. Kenda investigates a 1975 case that begins with the murder of a beloved Colorado philanthropist and society figure whose husband, a gambler and womanizer, appears to have an air-tight alibi. Mentored by his veteran partner Det. Lee Wilson, a former Nashville singer turned skilled investigator, Kenda’s case quickly attracts attention from the FBI, CIA, and Interpol, for its similarity to a string of killings involving wealthy married women. All the murders appear to have been committed by a hired professional.